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1.

Actin cytoskeleton remodeling primes RIG-I-like receptor activation.

Acharya, Dhiraj; Reis, Rebecca; Volcic, Meta; Liu, GuanQun; Wang, May K; Chia, Bing Shao; Nchioua, Rayhane; Groß, Rüdiger; Münch, Jan; Kirchhoff, Frank; Sparrer, Konstantin M J; Gack, Michaela U.

Cell; 185(19): 3588-3602.e21, 2022 09 15.

Artículo en Inglés | MEDLINE | ID: mdl-36113429

2.

Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity.

Chiang, Jessica J; Sparrer, Konstantin M J; van Gent, Michiel; Lässig, Charlotte; Huang, Teng; Osterrieder, Nikolaus; Hopfner, Karl-Peter; Gack, Michaela U.

Nat Immunol; 19(1): 53-62, 2018 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-29180807

3.

SARS-CoV-2 learned the 'Alpha'bet of immune evasion.

Liu, GuanQun; Gack, Michaela U.

Nat Immunol; 23(3): 351-353, 2022 03.

Artículo en Inglés | MEDLINE | ID: mdl-35194206

4.

Distinct and Orchestrated Functions of RNA Sensors in Innate Immunity.

Liu, GuanQun; Gack, Michaela U.

Immunity; 53(1): 26-42, 2020 07 14.

Artículo en Inglés | MEDLINE | ID: mdl-32668226

5.

Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation.

Chen, Da-Yuan; Chin, Chue Vin; Kenney, Devin; Tavares, Alexander H; Khan, Nazimuddin; Conway, Hasahn L; Liu, GuanQun; Choudhary, Manish C; Gertje, Hans P; O'Connell, Aoife K; Adams, Scott; Kotton, Darrell N; Herrmann, Alexandra; Ensser, Armin; Connor, John H; Bosmann, Markus; Li, Jonathan Z; Gack, Michaela U; Baker, Susan C; Kirchdoerfer, Robert N; Kataria, Yachana; Crossland, Nicholas A; Douam, Florian; Saeed, Mohsan.

Nature; 615(7950): 143-150, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36630998

6.

A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity.

Chan, Ying Kai; Gack, Michaela U.

Nat Immunol; 17(5): 523-30, 2016 May.

Artículo en Inglés | MEDLINE | ID: mdl-26998762

7.

Viral Anti-CRISPR Tactics: No Success without Sacrifice.

van Gent, Michiel; Gack, Michaela U.

Immunity; 49(3): 391-393, 2018 09 18.

Artículo en Inglés | MEDLINE | ID: mdl-30231980

8.

The RNA polymerase III-RIG-I axis in antiviral immunity and inflammation.

Naesens, Leslie; Haerynck, Filomeen; Gack, Michaela U.

Trends Immunol; 44(6): 435-449, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-37149405

9.

Viral evasion of the interferon response at a glance.

Zhu, Junji; Chiang, Cindy; Gack, Michaela U.

J Cell Sci; 136(12)2023 06 15.

Artículo en Inglés | MEDLINE | ID: mdl-37341132

10.

Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV.

van Gent, Michiel; Reich, Adrian; Velu, Sadanandan E; Gack, Michaela U.

PLoS Biol; 19(2): e3001097, 2021 02.

Artículo en Inglés | MEDLINE | ID: mdl-33596193

11.

Herpesvirus-mediated stabilization of ICP0 expression neutralizes restriction by TRIM23.

Liu, Xing; Acharya, Dhiraj; Krawczyk, Eric; Kangas, Chase; Gack, Michaela U; He, Bin.

Proc Natl Acad Sci U S A; 118(51)2021 12 21.

Artículo en Inglés | MEDLINE | ID: mdl-34903664

12.

The US3 Kinase of Herpes Simplex Virus Phosphorylates the RNA Sensor RIG-I To Suppress Innate Immunity.

van Gent, Michiel; Chiang, Jessica J; Muppala, Santoshi; Chiang, Cindy; Azab, Walid; Kattenhorn, Lisa; Knipe, David M; Osterrieder, Nikolaus; Gack, Michaela U.

J Virol; 96(4): e0151021, 2022 02 23.

Artículo en Inglés | MEDLINE | ID: mdl-34935440

13.

The herpesvirus accessory protein Î³134.5 facilitates viral replication by disabling mitochondrial translocation of RIG-I.

Liu, Xing; Ma, Yijie; Voss, Kathleen; van Gent, Michiel; Chan, Ying Kai; Gack, Michaela U; Gale, Michael; He, Bin.

PLoS Pathog; 17(3): e1009446, 2021 03.

Artículo en Inglés | MEDLINE | ID: mdl-33770145

14.

Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2.

Mou, Huihui; Quinlan, Brian D; Peng, Haiyong; Liu, Guanqun; Guo, Yan; Peng, Shoujiao; Zhang, Lizhou; Davis-Gardner, Meredith E; Gardner, Matthew R; Crynen, Gogce; DeVaux, Lindsey B; Voo, Zhi Xiang; Bailey, Charles C; Alpert, Michael D; Rader, Christoph; Gack, Michaela U; Choe, Hyeryun; Farzan, Michael.

PLoS Pathog; 17(4): e1009501, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33836016

15.

An optimized circular polymerase extension reaction-based method for functional analysis of SARS-CoV-2.

Liu, GuanQun; Gack, Michaela U.

Virol J; 20(1): 63, 2023 04 07.

Artículo en Inglés | MEDLINE | ID: mdl-37029393

16.

Prostaglandin E2: the villain in the host response to influenza virus.

Full, Florian; Gack, Michaela U.

Immunity; 40(4): 453-4, 2014 Apr 17.

Artículo en Inglés | MEDLINE | ID: mdl-24745327

17.

A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19.

Zhou, Yadi; Hou, Yuan; Shen, Jiayu; Mehra, Reena; Kallianpur, Asha; Culver, Daniel A; Gack, Michaela U; Farha, Samar; Zein, Joe; Comhair, Suzy; Fiocchi, Claudio; Stappenbeck, Thaddeus; Chan, Timothy; Eng, Charis; Jung, Jae U; Jehi, Lara; Erzurum, Serpil; Cheng, Feixiong.

PLoS Biol; 18(11): e3000970, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-33156843

18.

Reading the fine print: sequence-specific activation of cGAS.

Chiang, Jessica J; Gack, Michaela U.

Nat Immunol; 16(10): 1009-10, 2015 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-26382862

19.

FBXO38 Drives PD-1 to Destruction.

Serman, Taryn M; Gack, Michaela U.

Trends Immunol; 40(2): 81-83, 2019 02.

Artículo en Inglés | MEDLINE | ID: mdl-30609969

20.

Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling.

Wies, Effi; Wang, May K; Maharaj, Natalya P; Chen, Kan; Zhou, Shenghua; Finberg, Robert W; Gack, Michaela U.

Immunity; 38(3): 437-49, 2013 Mar 21.

Artículo en Inglés | MEDLINE | ID: mdl-23499489

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Actin cytoskeleton remodeling primes RIG-I-like receptor activation.

Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity.

SARS-CoV-2 learned the 'Alpha'bet of immune evasion.

Distinct and Orchestrated Functions of RNA Sensors in Innate Immunity.

Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation.

A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity.

Viral Anti-CRISPR Tactics: No Success without Sacrifice.

The RNA polymerase III-RIG-I axis in antiviral immunity and inflammation.

Viral evasion of the interferon response at a glance.

Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV.

Herpesvirus-mediated stabilization of ICP0 expression neutralizes restriction by TRIM23.

The US3 Kinase of Herpes Simplex Virus Phosphorylates the RNA Sensor RIG-I To Suppress Innate Immunity.

The herpesvirus accessory protein Î³134.5 facilitates viral replication by disabling mitochondrial translocation of RIG-I.

Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2.

An optimized circular polymerase extension reaction-based method for functional analysis of SARS-CoV-2.

Prostaglandin E2: the villain in the host response to influenza virus.

A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19.

Reading the fine print: sequence-specific activation of cGAS.

FBXO38 Drives PD-1 to Destruction.

Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling.