RESUMEN
CONCLUSIONS: The absence of recurrences after final nasal reconstruction demonstrates the reliability of our three-stage strategy and the necessity to delay nasal reconstruction, focusing attention on oncological safety for nasal non-melanoma skin cancer (NMSC) with mucosal invasion. OBJECTIVES: To validate a therapeutic strategy aimed at oncological safety and minimization of possible recurrences after full-thickness excision of nasal NMSC with mucosal invasion. The strategy was divided into three stages: surgical excision with clinically safe perilesional skin margins and extemporary frozen section histological control; 8-15 months follow-up leaving the nasal defect unreconstructed with a 'wait and see' strategy; new extemporary histological control of defect margins and, if negative, definitive reconstruction. PATIENTS AND METHODS: Twenty patients affected by nasal NMSC with mucosal invasion were treated and followed up. RESULTS: Basal cell carcinoma was the most common lesion (75%), followed by squamous cell carcinoma (25%). Ultrasonography excluded lymphatic involvement for SCC. Before final reconstruction, extemporary histological examination revealed the presence of tumour cells in three patients. After tumour extirpation, these patients were resubmitted to a new follow-up period before reconstruction. No recurrences were observed after definitive nasal reconstruction in all patients during the 5-year follow-up.
Asunto(s)
Carcinoma Basocelular/cirugía , Carcinoma de Células Escamosas/cirugía , Neoplasias Nasales/cirugía , Rinoplastia/métodos , Neoplasias Cutáneas/cirugía , Anciano , Carcinoma Basocelular/patología , Carcinoma de Células Escamosas/patología , Estudios de Cohortes , Femenino , Humanos , Masculino , Persona de Mediana Edad , Mucosa Nasal , Invasividad Neoplásica , Neoplasias Nasales/patología , Estudios Retrospectivos , Neoplasias Cutáneas/patología , Resultado del TratamientoRESUMEN
Discovered in 1830, paraffin oil, a purified hydrocarbon from petroleum, has been used in the past as an augmentation material in various parts of the human body, for restoration body defects or aesthetic body contouring. We illustrated the case of an 18-year-old guy who self-injected some paraffin oil (Baby Johnson's Oil) in his lips, cheek and chin, with aesthetical purpose. We showed the classical course and proper management of paraffinoma's lesions. The need for complete excision of all involved tissue to treat the condition successfully is illustrated, and a clinical, pathological and histological discussion is presented. To our knowledge paraffinoma of the face caused by a self-injection of mineral oil has been never reported in literature.