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1.

Feasibility, long-term safety, and immune monitoring of regulatory T cell therapy in living donor kidney transplant recipients.

Harden, Paul N; Game, David S; Sawitzki, Birgit; Van der Net, Jeroen B; Hester, Joanna; Bushell, Andrew; Issa, Fadi; Brook, Matthew O; Alzhrani, Alaa; Schlickeiser, Stephan; Scotta, Cristiano; Petchey, William; Streitz, Mathias; Blancho, Gilles; Tang, Quizhi; Markmann, James; Lechler, Robert I; Roberts, Ian S D; Friend, Peter J; Hilton, Rachel; Geissler, Edward K; Wood, Kathryn J; Lombardi, Giovanna.

Am J Transplant; 21(4): 1603-1611, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33171020

2.

Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.

Sawitzki, Birgit; Harden, Paul N; Reinke, Petra; Moreau, Aurélie; Hutchinson, James A; Game, David S; Tang, Qizhi; Guinan, Eva C; Battaglia, Manuela; Burlingham, William J; Roberts, Ian S D; Streitz, Mathias; Josien, Régis; Böger, Carsten A; Scottà, Cristiano; Markmann, James F; Hester, Joanna L; Juerchott, Karsten; Braudeau, Cecile; James, Ben; Contreras-Ruiz, Laura; van der Net, Jeroen B; Bergler, Tobias; Caldara, Rossana; Petchey, William; Edinger, Matthias; Dupas, Nathalie; Kapinsky, Michael; Mutzbauer, Ingrid; Otto, Natalie M; Öllinger, Robert; Hernandez-Fuentes, Maria P; Issa, Fadi; Ahrens, Norbert; Meyenberg, Christoph; Karitzky, Sandra; Kunzendorf, Ulrich; Knechtle, Stuart J; Grinyó, Josep; Morris, Peter J; Brent, Leslie; Bushell, Andrew; Turka, Laurence A; Bluestone, Jeffrey A; Lechler, Robert I; Schlitt, Hans J; Cuturi, Maria C; Schlickeiser, Stephan; Friend, Peter J; Miloud, Tewfik.

Lancet; 395(10237): 1627-1639, 2020 05 23.

Artículo en Inglés | MEDLINE | ID: mdl-32446407

3.

Regulatory T cell therapy for the induction of clinical organ transplantation tolerance.

Fan, Huimin; Cao, Peng; Game, David S; Dazzi, Francesco; Liu, Zhongmin; Jiang, Shuiping.

Semin Immunol; 23(6): 453-61, 2011 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-21920772

4.

Transplantation tolerance.

Salisbury, Emma M; Game, David S; Lechler, Robert I.

Pediatr Nephrol; 29(12): 2263-72, 2014 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-24213880

5.

Expert guidance on the multidisciplinary management of cystinosis in adolescent and adult patients.

Levtchenko, Elena; Servais, Aude; Hulton, Sally A; Ariceta, Gema; Emma, Francesco; Game, David S; Lange, Karin; Lapatto, Risto; Liang, Hong; Sberro-Soussan, Rebecca; Topaloglu, Rezan; Das, Anibh M; Webb, Nicholas J A; Wanner, Christoph.

Clin Kidney J; 15(9): 1675-1684, 2022 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-36003666

6.

Navigating COVID-19 in Renal Transplantation: From "Alpha" to "Omicron"; A Single-center Experience.

Sran, Kiran; Breen, Cormac; Ho, Garm Chi; Douthwaite, Samuel T; Calder, Francis; Game, David S; Olsburgh, Jonathon.

Transplantation; 106(6): e306-e307, 2022 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-35349535

7.

Generation and expansion of human CD4+ CD25+ regulatory T cells with indirect allospecificity: Potential reagents to promote donor-specific transplantation tolerance.

Jiang, Shuiping; Tsang, Julia; Game, David S; Stevenson, Saskia; Lombardi, Giovanna; Lechler, Robert I.

Transplantation; 82(12): 1738-43, 2006 Dec 27.

Artículo en Inglés | MEDLINE | ID: mdl-17198269

8.

Pathways of allorecognition: implications for transplantation tolerance.

Game, David S; Lechler, Robert I.

Transpl Immunol; 10(2-3): 101-8, 2002 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-12216939

9.

Regulatory T cells: the cunning fox and its clinical application.

Game, David S; Cao, Xuetao; Jiang, Shuiping.

Sci Signal; 1(51): mr3, 2008 Dec 23.

Artículo en Inglés | MEDLINE | ID: mdl-19109236

10.

Acquisition of HLA-DR and costimulatory molecules by T cells from allogeneic antigen presenting cells.

Game, David S; Rogers, Nicola J; Lechler, Robert I.

Am J Transplant; 5(7): 1614-25, 2005 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-15943619

11.

Activated CD1d-restricted natural killer T cells secrete IL-2: innate help for CD4+CD25+ regulatory T cells?

Jiang, Shuiping; Game, David S; Davies, Derek; Lombardi, Giovanna; Lechler, Robert I.

Eur J Immunol; 35(4): 1193-200, 2005 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-15770696

12.

Everolimus and basiliximab permit suppression by human CD4+CD25+ cells in vitro.

Game, David S; Hernandez-Fuentes, Maria P; Lechler, Robert I.

Am J Transplant; 5(3): 454-64, 2005 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-15707399

13.

Distinct effects of CD86-mediated costimulation on resting versus activated human CD4+ T cells.

Rogers, Nicola J; Game, David S; Camara, Niels O S; Jackson, Ian M; Lombardi, Giovanna; Lechler, Robert I.

Eur J Immunol; 35(10): 2909-19, 2005 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-16180251

14.

CD4+CD25+ regulatory T cells do not significantly contribute to direct pathway hyporesponsiveness in stable renal transplant patients.

Game, David S; Hernandez-Fuentes, Maria P; Chaudhry, Afzal N; Lechler, Robert I.

J Am Soc Nephrol; 14(6): 1652-61, 2003 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-12761268

15.

HLA-DR matching and immune regulation.

Game, David S; Lechler, Robert I.

Am J Transplant; 4(10): 1725-6, 2004 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-15367233

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