[Emergency surgery during COVID-19 pandemia.] / Cirugía de urgencia en urología durante la pandemia Covid-19.

INTRODUCTION: The crisis in the SARSCoV-2 coronavirus causing COVID-19 is putting health systems around the world to the test. In a great effort to standardize the management and treatment guidelines, the different health authorities and scientific associations have tried to issue recommendations on how to act in this new and complex scenario. OBJECTIVE: To synthesize the existing evidence and recommendations about urological emergency surgery during the COVID-19 pandemic situation. Furthermore, we propose a general action protocol for these patients. MATERIAL AND METHODS: The document is based ont he scarce evidence on SARS / Cov-2 and the experience of the authors in the management of COVID-19 in their institutions, including specialists from Andalusia, Cantabria, Madrid and the Basque Country. A web and PubMed search was performed using the keywords "SARS-CoV-2", "COVID19",  "COVID Urology", "COVID19 surgery" and "emergency care". A narrative review of the literature was carried out until April 30, 2020, including only articles and documents written in Spanish and English. After the nominal group technique modified due to the extraordinary restrictions, a first draft was made to unify criteria. Finally, a definitive version was made, agreed by all the authors on May 12, 2020. RESULTS: General principles of action are set out, as well as specific recommendations for the most frequent urgent urological procedures. CONCLUSIONS: Given the exceptional nature of the situation, there is a lack of evidence regarding the optimal management of the patient with urgent urological pathology. The information is changing, as the epidemiological knowledge of the disease advances. The establishment of multidisciplinary surgical committees that develop and implement action protocols appropriate to the different resources and particular situations of each center is recommended. Likewise, these committees must individually assess each possible urological surgical emergency situation and ensure compliance with protective measures for the patient and other healthcare personnel.

INTRODUCCIÓN: La crisis del coronavirus SARS-CoV-2 causante del COVID-19 está poniendoa prueba los sistemas sanitarios de todo el mundo. En un gran esfuerzo por estandarizar las pautas de manejo y tratamiento, las distintas autoridades sanitarias y asociaciones científicas han tratado de dictar unas recomendaciones sobre como actuar en este nuevo y complejo escenario.OBJETIVO: Sintetizar la evidencia y recomendaciones existentes acerca de la cirugía de urgencia urológica durante la situación de pandemia COVID-19. Además, proponemos un protocolo de actuación general para estos pacientes. MATERIAL Y MÉTODOS: El documento se basa en la escasa evidencia sobre SARS/Cov-2 y la experiencia de los autores en el manejo de COVID-19 en sus instituciones incluyendo especialistas de Andalucía, Cantabria, Madrid y País Vasco. Se realizó una búsqueda web y en PubMed utilizando las palabras clave "SARSCoV-2", "COVID19", "COVID Urology", "COVID19 surgery" y "emergency care". Se realizó una revisión narrativa de la literatura hasta el día 30 de Abril de2020 incluyendo solo artículos y documentos escritos en lengua española e inglesa. Tras técnica de grupo nominal modificada debido a las restricciones extraordinarias se realizó un primer borrador para unificar criterios. Finalmente, se realizó una versión definitiva, consensuada por todos los autores el 12 Mayo 2020. RESULTADOS: Se exponen unos principios generales de actuación, así como unas recomendaciones específicas para los procedimientos urológicos urgentes más frecuentes.CONCLUSIONES: Dado el carácter excepcional de la situación, existe un déficit de evidencia respecto al óptimo manejo del paciente con patología urológica urgente. La información es cambiante, según avanza el conocimiento epidemiológico de la enfermedad. Es recomendable el establecimiento de comités multidisciplinares quirúrgicos que desarrollen e implementen protocolos de actuación adecuados a los distintos recursos y situaciones particulares de cada centro. Del mismo modo, estos comités deben evaluar de forma individualizada cada posible situación de urgencia quirúrgica urológica y velar por el cumplimiento de las medidas de protección para el paciente y resto del personal sanitario.

Cirugía de urgencia en urología durante la pandemia Covid-19 / Emergency surgery during COVID-19 pandemia

INTRODUCCIÓN: La crisis del coronavirus SARS-CoV-2 causante del COVID-19 está poniendoa prueba los sistemas sanitarios de todo el mundo. En un gran esfuerzo por estandarizar las pautas de manejo y tratamiento, las distintas autoridades sanitarias y asociaciones científicas han tratado de dictar unas recomendaciones sobre como actuar en este nuevo y complejo escenario. OBJETIVO: Sintetizar la evidencia y recomendaciones existentes acerca de la cirugía de urgencia urológica durante la situación de pandemia COVID-19. Además, proponemos un protocolo de actuación general para estos pacientes. MATERIAL Y MÉTODOS: El documento se basa en la escasa evidencia sobre SARS/Cov-2 y la experiencia de los autores en el manejo de COVID-19 en sus instituciones incluyendo especialistas de Andalucía, Cantabria, Madrid y País Vasco. Se realizó una búsqueda web y en PubMed utilizando las palabras clave "SARSCoV-2", "COVID19", "COVID Urology", "COVID19 surgery" y "emergency care". Se realizó una revisión narrativa de la literatura hasta el día 30 de Abril de2020 incluyendo solo artículos y documentos escritos en lengua española e inglesa. Tras técnica de grupo nominal modificada debido a las restricciones extraordinarias se realizó un primer borrador para unificar criterios. Finalmente, se realizó una versión definitiva, consensuada por todos los autores el 12 Mayo 2020. RESULTADOS: Se exponen unos principios generales de actuación, así como unas recomendaciones específicas para los procedimientos urológicos urgentes más frecuentes. CONCLUSIONES: Dado el carácter excepcional de la situación, existe un déficit de evidencia respecto al óptimo manejo del paciente con patología urológica urgente. La información es cambiante, según avanza el conocimiento epidemiológico de la enfermedad. Es recomendable el establecimiento de comités multidisciplinares quirúrgicos que desarrollen e implementen protocolos de actuación adecuados a los distintos recursos y situaciones particulares de cada centro. Del mismo modo, estos comités deben evaluar de forma individualizada cada posible situación de urgencia quirúrgica urológica y velar por el cumplimiento de las medidas de protección para el paciente y resto del personal sanitario

INTRODUCTION: The crisis in the SARSCoV-2 coronavirus causing COVID-19 is putting health systems around the world to the test. In a great effort to standardize the management and treatment guidelines, the different health authorities and scientific associations have tried to issue recommendations on how to act in this new and complex scenario. OBJECTIVE: To synthesize the existing evidence and recommendations about urological emergency surgery during the COVID-19 pandemic situation. Furthermore, we propose a general action protocol for these patients. MATERIAL AND METHODS: The document is based on the scarce evidence on SARS/Cov-2 and the experience of the authors in the management of COVID-19 in their institutions, including specialists from Andalusia, Cantabria, Madrid and the Basque Country. A web and PubMed search was performed using the keywords "SARS-CoV-2", "COVID19", "COVID Urology", "COVID19 surgery" and "emergency care". A narrative review of the literature was carried out until April 30, 2020, including only articles and documents written in Spanish and English. After the nominal group technique modified due to the extraordinary restrictions, a first draft was made to unify criteria. Finally, a definitive version was made, agreed by all the authors on May 12, 2020. RESULTS: General principles of action are set out, as well as specific recommendations for the most frequent urgent urological procedures. CONCLUSIONS: Given the exceptional nature of the situation, there is a lack of evidence regarding the optimal management of the patient with urgent urological pathology. The information is changing, as the epidemiological knowledge of the disease advances. The establishment of multidisciplinary surgical committees that develop and implement action protocols appropriate to the different resources and particular situations of each center is recommended. Likewise, these committees must individually assess each possible urological surgical emergency situation and ensure compliance with rotective measures for the patient and other healthcare personnel

[Polyorchidism]. / Poliorquidismo.

OBJECTIVE: To report one case of supernumerary testicle, a rare entity with around 100 cases published. METHODS: 44-year-old male patient consulting for incidental discovering of a right scrotal mass. The diagnosis of polyorchidism was suspected after physical examination, ultrasound, and CT scan, and confirmed subsequently on surgical exploration and biopsy. Due to the absence of pathology and complete normal seminal lines decision was taken to not perform orchiectomy of the supernumerary testicle. RESULTS: There are classifications for proper evaluation of polyorchidism, which state the relation between site of the testicle in relation to scrotum, existence or absence of independent epididymis and vasa deferentia for both testicles. CONCLUSIONS: Although remotely, there is a possibility of malignant degeneration of these testicles, so that surgical exploration and excision of the supernumerary testicles when their biopsy is doubtful in terms of dysplasia or if they present carcinoma in situ or they are a source of pain.

[Metachronic testicular metastasis secondary to clear cell renal adenocarcinoma]. / Metástasis testicular metacrónica secundaria a adenocarcinoma renal de células claras.

OBJECTIVE: To report one case of unusual testicular metastasis from a renal origin. METHODS: 57 year-old patient with disseminated right renal cancer under treatment who presented bone metastasis and a painful nodule in the upper pole of the right testicle during his follow-up with medical therapy, making surgery necessary. The pathology result was clear cell adenocarcinoma. RESULTS: Six months later the patient continues under oral Sorafenib without evidence of new metastatic implants. CONCLUSIONS: Testicular secondary metastatic tumors account for less than 1% of old testicular tumors. In patients in the fifth and sixth decades, mainly if they are affected by other neoplasias, testicular masses use to be metastatic implants. The most frequent origin is prostate.

[Epithelioid renal angiomyolipoma]. / Angiomiolipoma epitelioide renal.

OBJECTIVE: To issue the existence of a variety of angiomyolipoma, named epithelioid, with different histological and clinic properties. METHODS: We report the case of a 17 year old female, with Bourneville's disease, who was discovered to have a solid renal mass suggestive of carcinoma in a control CT scan, adjacent to other smaller masses identified as angiomyolipomas. RESULTS: After several tumorectomies, the suspicious mass, 4 cm in size, was diagnosed as epithelioid angiomyolipoma, with immunohistochemical confirmation of capacity for HMB45, and negative vimentin and keratin. CONCLUSIONS: Despite the possibility of coexistence of adenocarcinoma and angiomyolipoma, the existence of an epithelioid variety cannot be discarded, mainly in patients with phakomatosis. The indications for surgery are the same than for the rest of renal masses. Nevertheless, follow-up criteria must be stricter due to the possibility of torpid outcome in terms of dissemination of this infrequent variety of angiomyolipoma.

[Neurological metastases secondary to germ cell testicular tumor]. / Metástasis neurológicas secundarias a tumor testicular germinal.

OBJECTIVE: Neurological metastases secondary to urological tumors account for 12% overall. The ones derived from germ cells testicular tumors are exceptional in the age of cisplatin. METHODS: We report one case of mixed germ cell tumor in a 49-year-old male patient treated with systemic chemotherapy during 18 months before presenting with severe central and peripheral neurological symptoms leading to death due to massive cerebral hemorrhage. RESULTS: We describe three types of presentation of cerebral metastases in patients with testicular cancer. Type I present synchronically with the primary tumor. Type 2 are diagnosed after a period of remission after conventional cytostatic treatment. Type 3 metastases are diagnosed during the course of the disease and its treatment. CONCLUSIONS: Except unique metastases classified in groups 1 and 2, which are susceptible of surgery or radiosurgery, in which in response may be expected; the rest of lesions secondary to germ cell tumors have an ominous prognosis and outcomes, with short survivals.

[Metastases in the paranasal sinuses secondary to prostatic adenocarcinoma]. / Metástasis en senos paranasales secundaria a adenocarcinoma prostático.

OBJECTIVE: To report a new case of exceptional metastases from a prostatic carcinoma. METHODS: 64-year-old male with nine months history of disseminated prostate cancer, taking hormonal treatment and biphosphonates, who presents with rising PSA, facial dysesthesia and left exophtalmos. MRI recognizes the existence of a solid mass in the right maxillary sinus with involvement of the ipsilateral orbital floor, and another one in the left frontal sinus invading the roof of the ipsilateral orbit and also with orbital extraconal involvement. RESULTS: Once the diagnosis was established hormonal maneuvers were performed and chemotherapy with docetaxel was administered achieving at the start of treatment measurable disease stabilization with biochemical remission of PSA levels, followed posteriorly by progression without changes in the metastatic images. Currently new cytoreductive therapy with docetaxel has been initiated. CONCLUSIONS: 1% of the prostatic tumors involve the head in their evolution. Most frequent metastases are localized in the brain and meninges, being the involvement of paranasal sinuses and ocular orbit extraordinary. The importance of these comes from the extension to the orbit and the eye in vicinity. Second line hormonal maneuvers, local radiotherapy and systemic chemotherapy will be necessary for control, although results are discouraging. In general, prognosis is poor, with short survival.

[Metachronic thyroid metastasis secondary to renal carcinoma. Case report]. / Metástasis tiroidea metacrónica secundaria a carcinoma renal. A propósito de un caso.

OBJECTIVE: We report the case of the patient with metachronic thyroid metastasis of a renal adenocarcinoma. METHODS: 61-year-old patient with the diagnosis of renal adenocarcinoma treated by radical nephrectomy (stage pT3bpN0M0) and subsequent interleukin-2 for twelve months presenting four years after surgery with a thyroid nodule displacing the trachea laterally, requiring left hemithyroidectomy. RESULTS: Pathology reported a lesion made of clear cytoplasm tumor cells, with marked atypia and anaplastic areas, compatible with clear cell renal adenocarcinoma. CONCLUSIONS: Thyroid metastases are extremely rare, being renal tumors the most frequent origin. They present as painless nodules, cold in gammagram, with normal thyroid hormones. The treatment of choice is surgical excision, with a better prognosis the longer the time between the primary and the appearance of metastasis.

Pliorquidismo / Polyorchidism

OBJETIVO: Presentamos un caso de teste supernumerario, rara entidad, de la que hay recogidos y fundamentados unos 100 casos.MÉTODOS: Se trata de un varón de 44 años, que consultó por descubrimiento casual de masa escrotal derecha. A la exploración física, ecográfica y tomográfica ya se sospechó el diagnóstico de poliorquidia, refrendándose posteriormente mediante exploración quirúrgica y biopsia. Dada la ausencia de patología y la completa normalidad de la línea seminal se optó por no actuar, no extirpando el teste supernumerario.RESULTADOS: Existen clasificaciones para una correcta evaluación de la poliorquidia, que relacionan la localización respecto a escroto, y la existencia o no de epidídimo y deferentes independientes para las dos gónadas.CONCLUSIONES: Aunque remota, existe la posibilidad de degeneración maligna en estos testes, por lo que se impone la exploración quirúrgica y la extirpación de los testes supernumerarios cuando la biopsia arroje dudas, en cuanto a displasia o presencia de carcinoma in situ, o cuando sean origen de dolor(AU)

OBJECTIVE: To report one case of supernumerary testicle, a rare entity with around 100 cases published.METHODS: 44-year-old male patient consulting for incidental discovering of a right scrotal mass. The diagnosis of polyorchidism was suspected after physical examination, ultrasound, and CT scan, and confirmed subsequently on surgical exploration and biopsy.Due to the absence of pathology and complete normal seminal lines decision was taken to not perform orchiectomy of the supernumerary testicle.RESULTS: There are classifications for proper evaluation of polyorchidism, which state the relation between site of the testicle in relation to scrotum, existence or absence of independent epididymis and vasa deferentia for both testicles.CONCLUSIONS: Although remotely, there is a possibility of malignant degeneration of these testicles, so that surgical exploration and excision of the supernumerary testicles when their biopsy is doubtful in terms of dysplasia or if they present carcinoma in situ or they are a source of pain(AU)

Metástasis neurológicas secundarias a tumor testicular germinal / Neurological metastases secondary to germ cell testicular tumor

Objetivo: Las metástasis neurológicas secundarias a tumores urológicos suponen un 12% del total. Las derivadas de los tumores germinales testiculares en la época del cisplatino son excepcionales. Métodos: Presentamos un caso de tumor germinal mixto en un varón de 49 años tratado mediante quimioterapia sistémica desde 18 meses antes que presentó severa clínica neurológica central y periférica, que le condujo a la muerte por hemorragia cerebral masiva. Resultados: Se describen 3 tipos de presentación de las metástasis cerebrales en pacientes con cáncer testicular. El tipo 1 en el que se presentan sincrónicamente al tumor primario. El tipo 2 en el que se diagnostican tras un período de remisión luego del tratamiento citostático convencional. En el tipo 3 las metástasis se diagnostican durante el curso de la enfermedad y durante su tratamiento. Conclusiones: Salvo en caso de metástasis únicas encuadradas en el grupo 1 y 2 susceptibles de cirugía o radiocirugía, en el que cabe esperar respuesta, en el resto de lesiones secundarias a tumores germinales la evolución y el pronóstico son ominosos, con supervivencias escasas (AU)

Objective: Neurological metastases secondary to urological tumors account for 12% overall. The ones derived from germ cells testicular tumors are exceptional in the age of cisplatin. Methods: We report one case of mixed germ cell tumor in a 49-year-old male patient treated with systemic chemotherapy during 18 months before presenting with severe central and peripheral neurological symptoms leading to death due to massive cerebral hemorrhage. Results: We describe three types of presentation of cerebral metastases in patients with testicular cancer. Type 1 present synchronically with the primary tumor. Type 2 are diagnosed after a period of remission after conventional cytostatic treatment. Type 3 metastases are diagnosed during the course of the disease and its treatment. Conclusions: Except unique metastases classified in groups I and 2, which are susceptible of surgery or radiosurgery, in which in response may be expected; the rest of lesions secondary to germ cell tumors have an ominous prognosis and outcomes, with short survivals (AU)

Tumor adenomatoide epididimario. Aportación de 5 casos / Adenomatoid tumor of the epididimys. Report of five cases

Objetivo: El tumor adenomatoide de epidídimo es infrecuente, de carácter benigno, no habiéndose descrito evoluciones malignas. Método: Presentamos 5 casos, con edades variopintas entre los 31 y los 76 años, y también con tamaños diversos entre los 6 y los 30 mm. Todos fueron intervenidos realizándose exéresis de la masa, tras varios meses de crecimiento. En un caso la evolución era de 6 años. Resultado: Ninguno presentó ni recidiva ni evolución tórpida tras la cirugía. La histología confirmó el carácter adenomatoide benigno en todos ellos. Conclusiones: A pesar de que los hallazgos clínicos, ecográficos y exploratorios sugieren la localización epididimaria y la benignidad, es mandatoria la exploración y extirpación quirúrgica de toda masa sólida paratesticular (AU)

Objective: Adenomatoid tumor of the epididymis is unfrequent, benign, with no malignant outcomes described. Methods: We report five cases, with patient's ages varying from 31 to 76 years, and tumor sizes from 6 to 30 mm. All patients underwent surgery with excision of the mass, some of them after several months of growing. In one of the cases the evolution reached six years. Results: None of the cases presented recurrence or bad outcome after surgery. Pathology confirmed the benign adenomatoid character in all cases. Conclusions: Despite the clinical, ultrasound and physical examination findings suggest the localization in the epididymis and its benign character, surgical exploration is mandatory with surgical excision of the paratesticular mass (AU)

Tumor de células de Sertoli maligno / Sertoli cell malignant tumor

Objetivo: Aportamos a la literatura un nuevo caso de tumor testicular compuesto por células de Sertoli de características histológicas malignas. Métodos: Se trata de un varón de 77 años, afecto de un síndrome general constitucional y una masa sólida testicular izquierda en la que tras la orquiectomía se diagnostica de tumor de células de Sertoli maligno, sin diseminación locorregional ni a distancia, con una benigna evolución tras 18 meses de seguimiento. Resultados: El tumor de células de Sertoli o androblastoma se encuadra en la clasificación de tumores no germinales derivados del estroma de los cordones sexuales. Se reconocen 3 tipos dependiendo de su composición celular: de célula grande calcificada, de célula esclerosada, y la más frecuente de todas, la variante clásica. Conclusiones: Siendo el tumor de células de Sertoli un tumor testicular poco común, la forma maligna lo es menos aún, no más del 10% del total. A pesar de las características patológicas que se relacionan con la malignidad, su comportamiento posterior es imprevisible y poco conocido, al igual que la forma de seguimiento y tratamiento, pues no es sensible a citostáticos. La presencia de metástasis sigue siendo hoy en día el único parámetro válido como valor pronóstico (AU)

Objective: We report a new case of Sertoli cell testicular tumor with malignant characteristics. Methods: 77-year-old male patient, suffering a general wasting syndrome presenting with a left solid testicular mass with the diagnosis of malignant Sertoli cell tumor after orchyectomy, without local, regional or distant dissemination, and a benign outcome after 18 months of follow-up. Results: Sertoli cell tumor or androblastoma is classified as non-germ cell tumor derived from the stroma of the sexual cords. There are three types depending on its cellular composition: calcified big cell, sclerotic cell, and the most frequent of all, the classic type. Conclusions: Being the Sertoli cell testicular tumor rare, its malignant type is even rarer, accounting for not more than 10% of all. Despite the pathological characteristics related to malignancy, its posterior behaviour is unpredictable and not much known, the same than follow-up and treatment, because it is not sensible to cytostatic drugs. The existence of metastases continues to be the only valid parameter with prognostic value (AU)

Metástasis tiroidea matacrónica secundaria a carcinoma renal. A propósito de un caso / Metachronic thyroid metastasis secondary to renal carcinoma. Case report

Objetivo: Presentamos el caso de una paciente con metástasis tiroidea metacrónica de un adenocarcinoma renal. Métodos: Paciente de 61 años, tratada mediante nefrectomía radical y posteriormente con interleukina-2 durante 12 meses por un adenocarcinoma renal, en estadío pT3b pN0 M0, que 4 años después desarrolla un nódulo tiroideo con desplazamiento tráqueal, que obligó a realizar una hemitiroidectomía izquierda. Resultados/Conclusiones: Histopatológicamente se informó como una lesión constituida por células tumorales con citoplasma claro, con acusada atipia y zonas anaplásicas compatible con adenocarcinoma renal de células claras. El estudio de extensión fue negativo. Conclusiones: Las metástasis tiroideas son extraordinariamente raras, siendo su origen renal el más frecuente. Se presentan como un nódulo indoloro, gammagráficamente frío, y niveles de hormonas tiroideas normales. Su tratamiento es la exéresis quirúrgica, con un pronóstico mejor cuanto mayor sea el tiempo trascurrido entre el tumor primario y la aparición de metástasis (AU)

Objective: We report the case of the patient with metachronic thyroid metastasis of a renal adenocarcinoma. Methods: 61-year-old patient with the diagnosis of renal adenocarcinoma treated by radical nephrectomy (stage pT3bpN0M0) and subsequent interleukin-2 for twelve months presenting four years after surgery with a thyroid nodule displacing the trachea laterally, requiring left hemithyroidectomy. Results: Pathology reported a lesion made of clear cytoplasm tumor cells, with marked atypia and anaplastic areas, compatible with clear cell renal adenocarcinoma. Conclusions: Thyroid metastases are extremely rare, being renal tumors the most frequent origin. They present as painless nodules, cold in gammagram, with normal thyroid hormones. The treatment of choice is surgical excision, with a better prognosis the longer the time between the primary and the appearance of metastasis (AU)

Metástasis en senos paranasales secundaria a adenocarcinoma prostático / Metastases in the paranasal sinuses secondary to prostatic adenocarcinoma

Objetivo: Presentar un nuevo caso de metástasis excepcional por carcinoma de próstata. Método: Varón de 64 años diagnosticado 9 meses antes de carcinoma prostático diseminado, en tratamiento hormonal además de bifosfonatos, que debuta con elevación de las cifras de PSA, disestesia facial y exoftalmos izquierdo. En RMN se reconoce la existencia de una masa sólida en seno maxilar derecho con afectación del suelo orbitario del mismo lado, y de otra de las mismas características localizada en seno frontal izquierdo con invasión del techo de la órbita homolateral y afectación extraconal orbitaria. Resultados: Una vez establecido el diagnóstico se sometió al paciente a maniobras hormonales y se administró quimioterapia con docetaxel obteniendo una estabilización de la enfermedad mensurable con una remisión bioquímica de los niveles del PSA al principio del tratamiento, para progresar posteriormente, sin observarse cambios en las imágenes metastásicas. En la actualidad se ha iniciado de nuevo terapia citorreductora con docetaxel. Conclusiones: El 1% de los tumores prostáticos afectarán la cabeza en su evolución. Las metástasis más frecuentes se localizan en cerebro y meninges, siendo la afectación de senos paranasales y órbita ocular extraordinaria. La importancia de éstas viene dada por la afectación en vecindad de la órbita y del ojo. Serán precisas para su control las maniobras hormonales de 2ª línea, la radioterapia local y la quimioterapia sistémica, aunque con resultados desalentadores. En general el pronóstico es malo, con sobrevivas cortas (AU)

Objective: To report a new case of exceptional metastases from a prostatic carcinoma. Methods: 64-year-old male with nine months history of disseminated prostate cancer, taking hormonal treatment and biphosphonates, who presents with rising PSA, facial dysesthesia and left exophtalmos. MRI recognizes the existence of a solid mass in the right maxillary sinus with involvement of the ipsilateral orbital floor, and another one in the left frontal sinus invading the roof of the ipsilateral orbit and also with orbital extraconal involvement. Results: Once the diagnosis was established hormonal maneuvers were performed and chemotherapy with docetaxel was administered achieving at the start of treatment measurable disease stabilization with biochemical remission of PSA levels, followed posteriorly by progression without changes in the metastatic images. Currently new cytoreductive therapy with docetaxel has been initiated. Conclusions: 1% of the prostatic tumors involve the head in their evolution. Most frequent metastases are localized in the brain and meninges, being the involvement of paranasal sinuses and ocular orbit extraordinary. The importance of these comes from the extension to the orbit and the eye in vicinity. Second line hormonal maneuvers, local radiotherapy and systemic chemotherapy will be necessary for control, although results are discouraging. In general, prognosis is poor, with short survival (AU)