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1.
Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.
J Biol Chem;
293(32): 12415-12428, 2018 08 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29925593
2.
Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease.
Pharmacol Rev;
68(3): 603-30, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27329045
3.
Processing and Maturation of Cathepsin C Zymogen: A Biochemical and Molecular Modeling Analysis.
Int J Mol Sci;
20(19)2019 Sep 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-31557781
4.
Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.
J Biol Chem;
291(16): 8486-99, 2016 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26884336
5.
New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases.
J Biol Chem;
289(46): 31777-31791, 2014 Nov 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-25288799
6.
Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice.
J Immunol;
188(9): 4476-87, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22461690
7.
Poly-L-Lysine compacts DNA, kills bacteria, and improves protease inhibition in cystic fibrosis sputum.
Am J Respir Crit Care Med;
188(6): 703-9, 2013 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23947381
8.
The pig as a model for investigating the role of neutrophil serine proteases in human inflammatory lung diseases.
Biochem J;
447(3): 363-70, 2012 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22860995
9.
Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.
Pharmacol Rev;
62(4): 726-59, 2010 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21079042
10.
Influence of DNA on the activities and inhibition of neutrophil serine proteases in cystic fibrosis sputum.
Am J Respir Cell Mol Biol;
47(1): 80-6, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22343221
11.
Three wavelength substrate system of neutrophil serine proteinases.
Anal Chem;
84(16): 7241-8, 2012 Aug 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-22823539
12.
A substrate-based approach to convert SerpinB1 into a specific inhibitor of proteinase 3, the Wegener's granulomatosis autoantigen.
FASEB J;
25(9): 3019-31, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21670065
13.
Cathepsin G and neutrophil elastase play critical and nonredundant roles in lung-protective immunity against Streptococcus pneumoniae in mice.
Infect Immun;
79(12): 4893-901, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21911460
14.
Structural characterization of mouse neutrophil serine proteases and identification of their substrate specificities: relevance to mouse models of human inflammatory diseases.
J Biol Chem;
284(49): 34084-91, 2009 Dec 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-19833730
15.
Human proteinase 3 resistance to inhibition extends to alpha-2 macroglobulin.
FEBS J;
287(18): 4068-4081, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31995266
16.
Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C.
Biochem Pharmacol;
164: 349-367, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30978322
17.
Neutrophil elastase, proteinase 3 and cathepsin G: physicochemical properties, activity and physiopathological functions.
Biochimie;
90(2): 227-42, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18021746
18.
Relationships between early inflammatory response to bleomycin and sensitivity to lung fibrosis: a role for dipeptidyl-peptidase I and tissue inhibitor of metalloproteinase-3?
Am J Respir Crit Care Med;
176(11): 1098-107, 2007 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17673693
19.
Exploiting the S4-S5 Specificity of Human Neutrophil Proteinase 3 to Improve the Potency of Peptidyl Di(chlorophenyl)-phosphonate Ester Inhibitors: A Kinetic and Molecular Modeling Analysis.
J Med Chem;
61(5): 1858-1870, 2018 03 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29442501
20.
Therapeutic targeting of cathepsin C: from pathophysiology to treatment.
Pharmacol Ther;
190: 202-236, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29842917