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1.
Sci Data ; 10(1): 654, 2023 09 23.
Artículo en Inglés | MEDLINE | ID: mdl-37741862

RESUMEN

The COVID-19 pandemic has made it clear: sharing and exchanging data among research institutions is crucial in order to efficiently respond to global health threats. This can be facilitated by defining health data models based on interoperability standards. In Germany, a national effort is in progress to create common data models using international healthcare IT standards. In this context, collaborative work on a data set module for microbiology is of particular importance as the WHO has declared antimicrobial resistance one of the top global public health threats that humanity is facing. In this article, we describe how we developed a common model for microbiology data in an interdisciplinary collaborative effort and how we make use of the standard HL7 FHIR and terminologies such as SNOMED CT or LOINC to ensure syntactic and semantic interoperability. The use of international healthcare standards qualifies our data model to be adopted beyond the environment where it was first developed and used at an international level.


Asunto(s)
COVID-19 , Humanos , Pandemias , Alemania , Instituciones de Salud , Humanidades
2.
Dtsch Med Wochenschr ; 147(3): 108-111, 2022 Jan.
Artículo en Alemán | MEDLINE | ID: mdl-35100643

RESUMEN

HISTORY: The 79-year-old patient was admitted with recurring fever, weight loss, night sweat, a decrease in physical capacity and hematomas of the extremities. FINDINGS: The patient presented with pancytopenia, elevated CRP and impaired renal function. A splenomegaly was evident in abdominal sonography. A bone marrow aspiration was performed. DIAGNOSIS: Histopathologic examination revealed a visceral Leishmaniasis. The diagnosis was confirmed by PCR from peripheral blood. THERAPY AND COURSE: After initiation of liposomal amphotericin B haematopoiesis recovered and CRP decreased. Initially the renal function deteriorated with prolongated improvement in the course of therapy. CONCLUSIONS: Pancytopenia and corresponding symptoms are suspect for visceral Leishmaniasis also in patients supposed to be immunocompetent with travel history of endemic regions.


Asunto(s)
Antiprotozoarios , Leishmaniasis Visceral , Pancitopenia , Anciano , Antiprotozoarios/uso terapéutico , Diagnóstico Diferencial , Fiebre/diagnóstico , Humanos , Leishmaniasis Visceral/complicaciones , Leishmaniasis Visceral/diagnóstico , Leishmaniasis Visceral/tratamiento farmacológico , Pancitopenia/diagnóstico , Pancitopenia/etiología , Esplenomegalia/diagnóstico , Esplenomegalia/tratamiento farmacológico
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