Detalles de la búsqueda
1.
Eco-Friendly Bio-Based Solvents for the Acetylation of the Amino Group of Amino Acids.
Chem Biodivers;
21(2): e202301729, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38241063
2.
Insights on the Modulation of SIRT5 Activity: A Challenging Balance.
Molecules;
27(14)2022 Jul 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35889322
3.
Towards the Inhibition of Protein-Protein Interactions (PPIs) in STAT3: Insights into a New Class of Benzothiadiazole Derivatives.
Molecules;
25(15)2020 Jul 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-32752073
4.
New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents.
J Enzyme Inhib Med Chem;
34(1): 823-828, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30889995
5.
Structure-based drug design, synthesis and biological assays of P. falciparum Atg3-Atg8 protein-protein interaction inhibitors.
J Comput Aided Mol Des;
32(3): 473-486, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29383466
6.
New Chromane-Based Derivatives as Inhibitors of Mycobacterium tuberculosis Salicylate Synthase (MbtI): Preliminary Biological Evaluation and Molecular Modeling Studies.
Molecules;
23(7)2018 06 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-29933627
7.
The response of Escherichia coli biofilm to salicylic acid.
Biofouling;
33(3): 235-251, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28270055
8.
Identification of a new STAT3 dimerization inhibitor through a pharmacophore-based virtual screening approach.
J Enzyme Inhib Med Chem;
31(6): 1011-7, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26308397
9.
Crystal structure of 3-(3-oxo-2,3,4,4a,5,6-hexa-hydro-benzo[h]cinnolin-2-yl)propionic acid.
Acta Crystallogr Sect E Struct Rep Online;
70(Pt 10): o1088-9, 2014 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25484687
10.
Structural basis for specific inhibition of salicylate synthase from Mycobacterium abscessus.
Eur J Med Chem;
265: 116073, 2024 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38169270
11.
Targeting Siderophore-Mediated Iron Uptake in M. abscessus: A New Strategy to Limit the Virulence of Non-Tuberculous Mycobacteria.
Pharmaceutics;
15(2)2023 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36839823
12.
The influence of the substitution pattern on the molecular conformation of ureido-1,2,5-oxadiazoles, related to STAT3 inhibitors: chemical behavior and structural investigation.
Chem Biodivers;
9(7): 1240-53, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22782873
13.
Synthesis and Assessment of the In Vitro and Ex Vivo Activity of Salicylate Synthase (Mbti) Inhibitors as New Candidates for the Treatment of Mycobacterial Infections.
Pharmaceuticals (Basel);
15(8)2022 Aug 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36015139
14.
Natural products against key Mycobacterium tuberculosis enzymatic targets: Emerging opportunities for drug discovery.
Eur J Med Chem;
224: 113732, 2021 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34399099
15.
Synthesis, Characterization, and Biological Evaluation of New Derivatives Targeting MbtI as Antitubercular Agents.
Pharmaceuticals (Basel);
14(2)2021 Feb 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-33668554
16.
Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design.
J Med Chem;
63(13): 7066-7080, 2020 07 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32530281
17.
Signal Transducer and Activator of Transcription Protein 3 (STAT3): An Update on its Direct Inhibitors as Promising Anticancer Agents.
Curr Med Chem;
26(27): 5165-5206, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30027840
18.
An Overview on the Potential Antimycobacterial Agents Targeting Serine/Threonine Protein Kinases from Mycobacterium tuberculosis.
Curr Top Med Chem;
19(9): 646-661, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30827246
19.
Exploring the Biological Activity of a Library of 1,2,5-Oxadiazole Derivatives Endowed With Antiproliferative Activity.
Anticancer Res;
39(1): 135-144, 2019 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-30591450
20.
Discovery of Novel Naphthylphenylketone and Naphthylphenylamine Derivatives as Cell Division Cycle 25B (CDC25B) Phosphatase Inhibitors: Design, Synthesis, Inhibition Mechanism, and in Vitro Efficacy against Melanoma Cell Lines.
J Med Chem;
62(15): 7089-7110, 2019 08 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31294975