RESUMEN
OBJECTIVE: To evaluate the occurrence of renal injury in hospitalized patients with the diagnosis of rhabdomyolysis among a series of patients presenting to an urban emergency department. METHODS: A retrospective chart review between January 2006 and February 2017 was conducted on patients aged 21-65â¯years old that were admitted with a diagnosis of Rhabdomyolysis. We included patients with an initial serum creatinine (Cr) levelâ¯<â¯1.3â¯mg/dL and an initial serum creatine phosphokinase (CPK) levelâ¯>â¯1000â¯U/L. We excluded patients with preexisting renal disease, hypertension, diabetes, patients currently on medications in the statin class, patients with muscular dystrophy and neuromuscular disorders. RESULTS: One hundred and fifteen patients (100 men, 15 women) were enrolled, with a mean age of 36â¯years old. The mean CPK at presentation was 18,965â¯U/L and the highest CPK was 168,300â¯U/L. The mean Cr upon presentation was 0.95â¯mg/dL. The average length of stay of our patients was 4.6â¯days. The longest length of stay was 30â¯days and the shortest was 1â¯day. Seven patients had hospital stays longer than 10â¯days. None of the patients had prolonged admissions due to rhabdomyolysis alone. The patient admitted for 30â¯days had a protracted admission due to liver failure and sepsis thought to be unrelated to Rhabdomyolysis. No patients that fit our inclusion criteria developed renal insufficiency (Crâ¯>â¯1.3â¯mg/dL) or failure regardless of their CPK upon presentation, peak CPK or therapies received during their hospitalization. CONCLUSION: Patients in our data set that presented to the Emergency Department with a CPK of >1000â¯U/L and a Cr of <1.3â¯mg/dL that were hospitalized with a diagnosis of rhabdomyolysis are not at risk for developing renal insufficiency or failure if treated promptly with fluid rehydration, regardless of their initial CPK values.