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1.
Inhibition of cholesterol biosynthesis in 3T3 fibroblasts by 2-aza-2,3-dihydrosqualene, a rationally designed 2,3-oxidosqualene cyclase inhibitor.
Biochem Pharmacol;
35(23): 4243-50, 1986 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-3790151
2.
Potent inhibition of cholesterol biosynthesis in 3T3 fibroblasts by N-[(1,5,9)-trimethyldecyl]-4 alpha,10-dimethyl-8-aza-trans-decal-3 beta-ol, a new 2,3-oxidosqualene cyclase inhibitor.
Biochem Pharmacol;
37(10): 1955-64, 1988 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-3377803
3.
Sterol synthesis. Synthesis of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluorocholest-5-en-7-one and its effects on HMG-CoA reductase activity in Chinese hamster ovary cells, on ACAT activity in rat jejunal microsomes, and serum cholesterol levels in rats.
Chem Phys Lipids;
94(2): 209-25, 1998 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-9779586
4.
Inhibitors of sterol synthesis. Synthesis and spectral properties of 3 beta-hydroxy-5 alpha-cholestan-15-one and its 17 beta-epimer and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.
Chem Phys Lipids;
74(1): 1-15, 1994 Oct 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-7820900
5.
Inhibitors of sterol synthesis: effects of a 7 alpha-alkyl analog of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells and on serum cholesterol levels and other parameters in rats.
Chem Phys Lipids;
70(2): 163-78, 1994 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-8033288
6.
Inhibitors of sterol synthesis: synthesis and spectral properties of derivatives of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluoro-5 alpha-cholest-8(14)-en-15-one fluorinated at carbon 7 or carbon 9 and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.
Chem Phys Lipids;
72(1): 59-75, 1994 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-7923480
7.
Inhibitors of sterol synthesis. Effects of fluorine substitution at carbon atom 25 of cholesterol on its spectral and chromatographic properties and on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
Steroids;
59(5): 310-7, 1994 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-8073444
8.
Inhibition by the fungicide fenpropimorph of cholesterol biosynthesis in 3T3 fibroblasts.
Biochem J;
256(3): 829-34, 1988 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-3223956
9.
Silver ion high pressure liquid chromatography provides unprecedented separation of sterols: application to the enzymatic formation of cholesta-5,8-dien-3 beta-ol.
Proc Natl Acad Sci U S A;
93(21): 11603-8, 1996 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-8876182
10.
An updated look at the analysis of unsaturated C27 sterols by gas chromatography and mass spectrometry.
J Lipid Res;
38(8): 1685-701, 1997 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-9300791
11.
Sterol synthesis. A timely look at the capabilities of conventional and silver ion high performance liquid chromatography for the separation of C27 sterols related to cholesterol biosynthesis.
J Lipid Res;
38(12): 2615-26, 1997 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-9458284
12.
Inhibitors of sterol synthesis. Effects of a new fluorinated analog of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one in rats.
J Lipid Res;
35(6): 1040-56, 1994 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-8077843
13.
Inhibitors of sterol synthesis. Chemical synthesis and properties of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluoro-5 alpha-cholest-8(14)-en-15-one and 25,26,26,26,27,27,27-heptafluorocholesterol and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.
J Lipid Res;
34(10): 1805-23, 1993 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-8245728
14.
Inhibitors of sterol synthesis: 3 beta-hydroxy-25,26,26,26,27,27,27- heptafluoro-5 alpha-cholestan-15-one, an analog of a potent hypocholesterolemic agent in which its major metabolism is blocked.
Biochem Biophys Res Commun;
201(1): 168-73, 1994 May 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-8198571
15.
Inhibitors of sterol synthesis. Metabolism-based design and construction of a new analog of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and its effects in cultured mammalian cells and in rats.
J Lipid Res;
36(4): 767-86, 1995 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-7616123
16.
Sterols in blood of normal and Smith-Lemli-Opitz subjects.
J Lipid Res;
42(5): 799-812, 2001 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-11352988
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