Detalles de la búsqueda
1.
Evaluation of [¹8F]MK-0911, a positron emission tomography (PET) tracer for opioid receptor-like 1 (ORL1), in rhesus monkey and human.
Neuroimage;
68: 1-10, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23238431
2.
Benzodiazepine binding site occupancy by the novel GABAA receptor subtype-selective drug 7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023) in rats, primates, and humans.
J Pharmacol Exp Ther;
332(1): 17-25, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19779131
3.
In vitro and in vivo properties of 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA receptor alpha5 subtype-selective inverse agonist.
J Pharmacol Exp Ther;
331(2): 470-84, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19704033
4.
Discovery of N-{(1S,2S)-2-(3-cyanophenyl)- 3-[4-(2-[18F]fluoroethoxy)phenyl]-1-methylpropyl}- 2-methyl-2-[(5-methylpyridin-2-yl)oxy]propanamide, a cannabinoid-1 receptor positron emission tomography tracer suitable for clinical use.
J Med Chem;
50(15): 3427-30, 2007 Jul 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-17608398
5.
Species differences in mGluR5 binding sites in mammalian central nervous system determined using in vitro binding with [18F]F-PEB.
Nucl Med Biol;
34(8): 1009-17, 2007 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-17998106
6.
Screening cascade and development of potential Positron Emission Tomography radiotracers for mGluR5: in vitro and in vivo characterization.
Mol Imaging Biol;
7(4): 314-23, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-16080024
7.
A cell-based radioligand binding assay for farnesyl: protein transferase inhibitors.
J Biomol Screen;
8(4): 430-8, 2003 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-14567795
8.
An in vitro assay for predicting successful imaging radiotracers.
Mol Imaging Biol;
5(2): 65-71, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-14499146
9.
Hepatic glucagon receptor binding and glucose-lowering in vivo by peptidyl and non-peptidyl glucagon receptor antagonists.
Eur J Pharmacol;
501(1-3): 225-34, 2004 Oct 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-15464082
10.
Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.
Cancer Res;
70(6): 2476-84, 2010 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20197467
11.
In vitro characterization of a gamma-secretase radiotracer in mammalian brain.
J Neurochem;
96(1): 171-8, 2006 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-16300641
12.
Synthesis, characterization, and first successful monkey imaging studies of metabotropic glutamate receptor subtype 5 (mGluR5) PET radiotracers.
Synapse;
56(4): 205-16, 2005 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15803497
13.
Generation and characterization of a human bradykinin receptor B1 transgenic rat as a pharmacodynamic model.
J Pharmacol Exp Ther;
310(2): 488-97, 2004 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15051800
Resultados
1 -
13
de 13
1
Próxima >
>>