Asunto(s)
Púrpura Fulminante/microbiología , Púrpura Fulminante/terapia , Infecciones Estafilocócicas/microbiología , Infecciones Estafilocócicas/terapia , Biopsia , Diagnóstico Diferencial , Humanos , Recién Nacido , Masculino , Índice de Severidad de la Enfermedad , Trasplante de Piel , Staphylococcus aureus/aislamiento & purificaciónRESUMEN
An unusual case of malignant cylindroma of the scalp arising in a 79-year-old white female with multiple cylindromatosis is presented. The tumor apparently arose from a cylindroma and had features of spiradenoma. Multiple cylindromatosis is an uncommon hereditary autosomal dominant disease, which is characterized by multiple skin adnexal tumors like cylindromas and trichoepitheliomas and occasional spiradenomas. Cylindroma is an uncommon benign tumor, which originates from skin appendages and is most commonly found on the scalp and face with a strong predilection for middle-aged and elderly females. Although cylindromas are usually benign neoplasms, carcinoma arising in such neoplasms is rare with only sporadic reports in literature. Her family history was negative for a similar disease. The patient's main concern was painful lesions over her right ear that interfered with wearing of her glasses. The clinical, histological immunohistochemical features, and treatment are presented along with a review of the literature.
Asunto(s)
Carcinoma Adenoide Quístico/patología , Neoplasias Primarias Múltiples/patología , Cuero Cabelludo/patología , Neoplasias Cutáneas/patología , Anciano , Femenino , HumanosAsunto(s)
Quimioradioterapia/efectos adversos , Huésped Inmunocomprometido , Neoplasias Pulmonares/tratamiento farmacológico , Neutropenia/inducido químicamente , Neutropenia/complicaciones , Carcinoma Pulmonar de Células Pequeñas/tratamiento farmacológico , Tiña/etiología , Antifúngicos/uso terapéutico , Protocolos de Quimioterapia Combinada Antineoplásica/administración & dosificación , Protocolos de Quimioterapia Combinada Antineoplásica/efectos adversos , Femenino , Fluconazol/administración & dosificación , Granuloma/tratamiento farmacológico , Granuloma/microbiología , Granuloma/patología , Humanos , Itraconazol/administración & dosificación , Neoplasias Pulmonares/diagnóstico , Persona de Mediana Edad , Carcinoma Pulmonar de Células Pequeñas/diagnóstico , Tiña/inmunología , Tiña/microbiología , Tiña/patologíaRESUMEN
Basal cell carcinoma (BCC) is a rare disease in the pediatric population that usually presents in children with predisposing genetic conditions. It is often diagnosed on final pathology of an excisional biopsy, and the treatment may be delayed in younger populations because of a physician's low index of suspicion. Increased knowledge of BCC by pediatric caregivers would expedite definitive therapy for childhood BCC as well as any necessary evaluation by subspecialists for predisposing syndromes. We report 3 cases of BCC in pediatric patients and review the literature concerning BCC in children.