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1.
Anesthesiology ; 112(5): 1164-74, 2010 May.
Artículo en Inglés | MEDLINE | ID: mdl-20418697

RESUMEN

BACKGROUND: Health-related quality of life is usually reported for specific rather than heterogeneous populations such as those treated in routine anesthesia practice. The 8-item short-form generic health-related quality-of-life questionnaire (SF-8) is a candidate instrument for this setting. The authors evaluated the feasibility, reliability, validity, and responsiveness to change of the Spanish version of SF-8 in a population-based surgical cohort. METHODS: Recruiting patients from a large population-based study of risk factors for pulmonary complications, before surgery, the authors administered the 1-week recall SF-8 to 2,991 patients undergoing nonobstetric elective or emergency surgery in 59 hospitals, each of which collected data on seven randomly assigned days in 2006. The SF-8 was administered again 3 months later. Reliability was evaluated using the Cronbach alpha coefficient and validity by comparing physical and mental component summary SF-8 scores with clinical variables. Responsiveness after surgery was evaluated using the standardized response mean. RESULTS: Cronbach alpha for the overall test was 0.92. Physical and mental component summary scores and all individual scores were lower (worse quality of life) in women (P < 0. 01) and decreased with age (P < 0.01). Preoperative scores were lower for those in worse clinical condition (higher body mass index, American Society of Anesthesiologists physical status class, or surgical risk scores), with preoperative respiratory symptoms, and in emergency situations (P < 0.01). The standardized response mean ranged from 0.1 to 0.5. CONCLUSIONS: The SF-8 is a feasible, reliable, valid, and responsive instrument for assessing health-related quality of life in a broad-spectrum surgical population.


Asunto(s)
Estado de Salud , Encuestas Epidemiológicas , Multilingüismo , Calidad de Vida , Procedimientos Quirúrgicos Operativos , Encuestas y Cuestionarios/normas , Adulto , Anciano , Estudios de Cohortes , Estudios Transversales , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Calidad de Vida/psicología , España , Procedimientos Quirúrgicos Operativos/psicología
2.
Anesthesiology ; 113(6): 1338-50, 2010 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-21045639

RESUMEN

BACKGROUND: Current knowledge of the risk for postoperative pulmonary complications (PPCs) rests on studies that narrowly selected patients and procedures. Hypothesizing that PPC occurrence could be predicted from a reduced set of perioperative variables, we aimed to develop a predictive index for a broad surgical population. METHODS: Patients undergoing surgical procedures given general, neuraxial, or regional anesthesia in 59 hospitals were randomly selected for this prospective, multicenter study. The main outcome was the development of at least one of the following: respiratory infection, respiratory failure, bronchospasm, atelectasis, pleural effusion, pneumothorax, or aspiration pneumonitis. The cohort was randomly divided into a development subsample to construct a logistic regression model and a validation subsample. A PPC predictive index was constructed. RESULTS: Of 2,464 patients studied, 252 events were observed in 123 (5%). Thirty-day mortality was higher in patients with a PPC (19.5%; 95% [CI], 12.5-26.5%) than in those without a PPC (0.5%; 95% CI, 0.2-0.8%). Regression modeling identified seven independent risk factors: low preoperative arterial oxygen saturation, acute respiratory infection during the previous month, age, preoperative anemia, upper abdominal or intrathoracic surgery, surgical duration of at least 2 h, and emergency surgery. The area under the receiver operating characteristic curve was 90% (95% CI, 85-94%) for the development subsample and 88% (95% CI, 84-93%) for the validation subsample. CONCLUSION: The risk index based on seven objective, easily assessed factors has excellent discriminative ability. The index can be used to assess individual risk of PPC and focus further research on measures to improve patient care.


Asunto(s)
Enfermedades Pulmonares/diagnóstico , Complicaciones Posoperatorias/diagnóstico , Adulto , Anciano , Anciano de 80 o más Años , Anestesia , Estudios de Cohortes , Recolección de Datos/normas , Femenino , Humanos , Tiempo de Internación , Modelos Logísticos , Enfermedades Pulmonares/epidemiología , Enfermedades Pulmonares/mortalidad , Masculino , Persona de Mediana Edad , Población , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/mortalidad , Valor Predictivo de las Pruebas , Estudios Prospectivos , Respiración Artificial , Factores de Riesgo , Tamaño de la Muestra , Estaciones del Año , España/epidemiología , Resultado del Tratamiento
3.
Medicine (Baltimore) ; 99(11): e19101, 2020 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-32176037

RESUMEN

Mirror image sensory dysfunction (MISD) after breast surgery has not yet been studied. This prospective observational study aimed to determine the incidence of MISD, persistent postoperative pain (PPP) and mirror image pain (MIP) during 6 months after total unilateral mastectomy.Visual analogue scale (VAS), Neuropathic Pain Symptom Inventory (NPSI), Pain Catastrophizing Scale (PCS), Hospital Anxiety and Depression Scale (HADS), Life orientation test (LOT) and Quantitative Sensory Testing (QST) (in ipsi and contralateral breast, axilla and thigh) were recorded. VAS > 3 at 1, 3, and 6 postoperative months was considered PPP. Contralateral changes of QST at any time was considered indicative of MISD and spontaneous contralateral VAS ≥ 1 as MIP.Sixty-four patients were included. PPP at 1, 3 and 6 months was 18.8%, 56.2%, and 21.3%, respectively Ten patients presented MIP. MISD was detected in 79.7% patients in contralateral breast and 62.5% in contralateral axilla. Furthermore, changes in QST were present in 39.1% of patients in thigh. Electronic Von Frey (EVF) changes in both contralateral breast and axilla, and in thigh significantly diminished at all postoperative times. Changes of postoperative EVF ≥ 20% in contralateral breast were associated to higher VAS values. NPSI scores were significantly higher at all postoperative times. At 1 month, PCS, depression HADS subscale and LOT scores were significantly worse than all the other periods.MISD incidence was almost 80%, and 15.6% of patients showed spontaneous contralateral VAS ≥ 1. At 6 months 21.3% of patients manifested PPP. The worst alteration of factors related to PPP occurred at 1 postoperative month. Most consistent QST was EVF.


Asunto(s)
Mastectomía/efectos adversos , Neuralgia/etiología , Dolor Postoperatorio/etiología , Femenino , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Neuralgia/epidemiología , Dimensión del Dolor , Dolor Postoperatorio/epidemiología , Estudios Prospectivos , Encuestas y Cuestionarios
4.
Med Teach ; 31(5): e189-95, 2009 May.
Artículo en Inglés | MEDLINE | ID: mdl-19241215

RESUMEN

BACKGROUND: There is no evidence on the best method for teaching Basic Life Support (BLS). AIMS: To compare two methods for teaching BLS, assessing the level of cognitive skills. METHODS: Randomized, prospective study including 68 medical students. BLS algorithms were taught for 60 minutes using either a multimedia presentation (Group I, n=34) or case based discussion (Group II, n=34). Assessments included a scenario-based quiz test and an error-pinpointing video, which the students completed before (T1) and after (T2) teaching. Comparisons between both groups were made on scores of the assessments, actual increases in scores (final value - initial value) and score gains (actual increase/potential increase). RESULTS: No significant differences were found between the groups in any of the recorded scores. Both groups improved their T2 scores (p values <0.001). The actual increases in scores and the score gains were similar in both groups. Test scores improved in 55.9% of students in Group I and 58.8% in Group II; video scores improved in 85.3% of Group I and in 82.3% of Group II. CONCLUSIONS: BLS teaching by either multimedia presentations or case based discussion equally improves the level of cognitive skills among medical students.


Asunto(s)
Algoritmos , Cognición , Educación de Pregrado en Medicina , Cuidados para Prolongación de la Vida , Multimedia , Estudiantes de Medicina/psicología , Enseñanza/métodos , Femenino , Humanos , Masculino , Estudios Prospectivos , Adulto Joven
5.
Resuscitation ; 134: 127-132, 2019 01.
Artículo en Inglés | MEDLINE | ID: mdl-30428308

RESUMEN

BACKGROUND: The use of online teaching methodology for basic life support (BLS) courses is progressively increasing. OBJECTIVE: The objective of this study was to verify whether the blended-learning methodology (virtual course with a short face-to-face complement) was more efficient than a course that followed the classical or face-to-face methodology in our university. MATERIALS AND METHODS: A cost minimization analysis was performed for two BLS and automatic external defibrillation (AED) courses, one of which was conducted face-to-face (Control Group) and the second of which was conducted via blended-learning (Experimental Group). The courses had the same duration and content according to the European Resuscitation Council (ERC) recommendations. In the face-to-face course, direct costs were considered those generated by the faculty and derived from the academic activity. Other costs were those generated by the use of classrooms and the amortization of manikins and AED training. The perspective of the analysis was that of the provider, the academic, and a time horizon of six months. The costs are expressed in € 2017. RESULTS: The savings of a course in BLS-AED based on the blended-learning methodology calculated for a total of 160 university nursing and medical students were € 2328.8 for the first year of its implementation and € 9048.8 for its second edition compared with the same course using a face-to-face methodology. CONCLUSIONS: The blended-learning methodology supposes a cost savings for BLS-AED courses, mainly due to the reduction of expenses of the teaching staff. The blended-learning methodology seems to be more efficient than the face-to-face methodology.


Asunto(s)
Reanimación Cardiopulmonar/educación , Instrucción por Computador/economía , Costos y Análisis de Costo , Adolescente , Adulto , Evaluación Educacional , Femenino , Humanos , Masculino , Paro Cardíaco Extrahospitalario/terapia , Adulto Joven
6.
Med Teach ; 30(7): 693-8, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-18608952

RESUMEN

BACKGROUND: In 2001, in order to improve the curriculum, the medical school of the University of Barcelona began discussions aimed at defining specific learning outcomes for its medical graduates and, subsequently, evaluating the acquisition of these competencies. AIM: To report the views of our medical students regarding the extent to which they have acquired the learning outcomes previously defined by the faculty. METHOD: A questionnaire was administered to seventy final year students, who had finished all the course clerkships and they were asked to indicate on a Likert scale their perceived level of acquisition of each learning outcome. RESULTS: Overall, the students report an adequate level of competency and consider themselves able to meet skills targets under supervision in eight of the eleven domains investigated. In three of the domains (patient management, medical information search skills, and decision-making skills and clinical reasoning and judgment) students regarded themselves as only partially competent. These results agree with the global course score of the students, according to the medical school assessment system. CONCLUSIONS: The results will allow us to make curricular and methodological changes in order to implement a new outcome-based curriculum.


Asunto(s)
Competencia Clínica , Evaluación Educacional/métodos , Facultades de Medicina , Estudiantes de Medicina/psicología , Recolección de Datos , Femenino , Humanos , España
7.
Nurse Educ Today ; 65: 232-238, 2018 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-29605787

RESUMEN

AIM OF THE STUDY: The objective of this study was to compare the immediate and 6-month efficacy of basic life support (BLS) and automatic external defibrillation (AED) training using standard or blended methods. METHODS: First-year students of medicine and nursing (n = 129) were randomly assigned to a control group (face-to-face training based on the European Resuscitation Council [ERC] Guidelines) or to an experimental group that trained with a self-training video, a new website, a Moodle platform, an intelligent manikin, and 45 min of instructor presence. Both groups were homogeneous and were evaluated identically. Theoretical knowledge was evaluated using a multi-choice questionnaire (MCQ). Skill performance was evaluated by the instructor's rubric and on a high-fidelity Resusci Anne QCPR manikin. RESULTS: Immediately after the course, there were no statistically significant differences in knowledge between the two groups. The median score of practical evaluation assessed by the instructor was significantly better in the experimental group (8.15, SD 0.93 vs 7.7, SD 1.18; P = 0.02). No differences between groups were found when using a high-fidelity manikin to evaluate chest compressions and lung inflations. At six months, the scores in knowledge and skill performance were significantly lower compared to the evaluations at the end of the instruction, but they remained still higher compared to baseline. The experimental group had higher scores in practical skills evaluated by the instructor than the control group (7.44, SD 1.85 vs 6.10, SD 2.6; P = 0.01). CONCLUSIONS: The blended method provides the same or even higher levels of knowledge and skills than standard instruction both immediately after the course and six months later.


Asunto(s)
Reanimación Cardiopulmonar/educación , Competencia Clínica/normas , Desfibriladores/psicología , Estudiantes/psicología , Enseñanza/normas , Reanimación Cardiopulmonar/métodos , Evaluación Educacional/métodos , Femenino , Humanos , Masculino , Investigación Cualitativa , Estadísticas no Paramétricas , Adulto Joven
8.
Medicine (Baltimore) ; 96(15): e6624, 2017 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-28403113

RESUMEN

Studies designed to assess persistent postoperative pain (PPP) incidence after hepatectomies are lacking. Our aim was to assess PPP incidence 6 months after hepatectomies with intravenous (IV) or epidural (EPI) analgesia containing ketamine.Prospective observational comparative study between 2 cohorts of patients submitted to hepatectomy. Patients received 1 of 2 analgesic regimes containing ketamine: EPI group or IV group. Visual analog scale (VAS), Neuropathic Pain Symptom Inventory (NPSI), Pain Catastrophizing Scale (PCS), and quantitative sensorial testing (QST: to determine area of hyperalgesia/allodynia) were assessed preoperatively and postoperatively at 2 h, 24 h, 7 days, 1 month, and 6 months. VAS ≥ 1 at 1 and 6 months was considered indicative of PPP and VAS > 3 was considered as not controlled pain. Side effects and complications were registered.Forty-four patients were included: 23 in EPI group and 21 in IV group. Patients in IV group were older and had more comorbidities. No patient presented VAS > 3 at 1 or 6 months. VAS ≥ 1 at 1 and 6 months was 36.4% and 22.7%, respectively. No differences in VAS, NPSI, or PCS were found between groups. Allodynia/hyperalgesia area did not differ between groups and was infrequent and slight. Pain pressure threshold in the wound vertical component was significantly higher in EPI group after 7 days. IV group showed more cognitive side effects.Incidence of PPP at 6 months after open hepatectomies with EPI or IV analgesia containing ketamine was lower than previously reported for other abdominal surgeries.Ketamine influence on low PPP incidence and hyperalgesia cannot be discarded.


Asunto(s)
Analgésicos/administración & dosificación , Hepatectomía/efectos adversos , Hiperalgesia/epidemiología , Ketamina/administración & dosificación , Dolor Postoperatorio/epidemiología , Anciano , Femenino , Hepatectomía/métodos , Humanos , Hiperalgesia/etiología , Hiperalgesia/prevención & control , Incidencia , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Dolor Postoperatorio/etiología , Dolor Postoperatorio/prevención & control , Atención Perioperativa/métodos , Periodo Posoperatorio , Estudios Prospectivos , Factores de Tiempo , Resultado del Tratamiento
9.
Reg Anesth Pain Med ; 31(5): 438-44, 2006.
Artículo en Inglés | MEDLINE | ID: mdl-16952816

RESUMEN

BACKGROUND: The safety of ketamine when administered by the spinal route must be confirmed in various animal species before it is approved for use in humans. This study evaluates the ultrastructure of canine meninges after repeated doses of epidural S(+)-ketamine. METHODS: Five dogs received S(+)-ketamine 5%, 1 mg/kg, twice a day for 10 days through an epidural catheter with its tip located at the L5 level. One dog received the same volume of normal saline at the same times. The spinal cord and meninges were processed for histopathological and ultrastructural studies. Clinical effects were assessed after each injection. RESULTS: Motor and sensory block appeared after each injection of S(+)-ketamine, but not in the dog receiving saline. No signs of clinical or neurologic alterations were observed. Using light microscopy, no meningeal layer showed alterations except focal infiltration at the catheter tip level by macrophages, lymphocytes, and a few mast cells. The cells of different layers were studied by electron microscopy and interpreted according to data from human and other animal species because no ultrastructural description of the canine meninges is currently available. There were no cellular signs of inflammation, phagocytosis, or degeneration in meningeal layers and no signs of atrophy, compression, or demyelinization in the areas of dorsal root ganglia and spinal cord around the arachnoid. These findings were common for dogs receiving S(+)-ketamine and the dog receiving saline. CONCLUSION: Repeated doses of epidural S(+)-ketamine 5%, 1 mg/kg, twice a day for 10 days was not associated to cellular alterations in canine meninges.


Asunto(s)
Inyecciones Epidurales , Ketamina/administración & dosificación , Ketamina/toxicidad , Meninges/efectos de los fármacos , Animales , Perros , Femenino , Meninges/ultraestructura , Estereoisomerismo
10.
Am J Vet Res ; 66(1): 54-61, 2005 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-15691036

RESUMEN

OBJECTIVE: To evaluate the analgesic and adverse effects of epidurally administered levogyral (S[+]) ketamine alone or in combination with morphine on intraoperative and postoperative pain in dogs undergoing ovariohysterectomy. ANIMALS: 30 dogs scheduled for ovariohysterectomy. PROCEDURE: Dogs were randomly allocated to 1 of 3 groups. Dogs in group 1 received S(+) ketamine (1 mg/kg), dogs in group 2 received S(+) ketamine (0.5 mg/kg) and morphine (0.05 mg/kg), and dogs in group 3 received S(+) ketamine (1 mg/kg) and morphine (0.025 mg/kg). The skin was incised 15 minutes after epidural administration of analgesics. Heart rate (HR), respiratory rate (RR), systolic blood pressure (SBP), oxygen saturation as measured by pulse oximetry, and arterial blood gases were obtained before anesthesia, 15 minutes after epidural administration of analgesics, 15 and 30 minutes after initiation of surgery, and at the end of surgery. During the intraoperative period, an increase of > or =20% in baseline values for HR, RR, and SBP was considered a sign of intraoperative pain. Signs of pain and adverse effects were assessed at 2, 4, and 8 hours postoperatively. RESULTS: There were no significant differences in intraoperative or postoperative measurements among the 3 groups. No dogs had intraoperative signs of pain. Mean postoperative pain assessment scores were <3.5 in all 3 groups. Salivation was the most frequent adverse effect in dogs in groups 1 and 3, and sedation occurred more frequently in dogs in groups 2 and 3. CONCLUSIONS AND CLINICAL RELEVANCE: All 3 analgesic regimens provided good respiratory and cardiovascular stability intraoperatively and adequate postoperative analgesia with minimal adverse effects.


Asunto(s)
Analgesia Epidural/veterinaria , Analgésicos/uso terapéutico , Perros/cirugía , Ketamina/uso terapéutico , Morfina/uso terapéutico , Analgésicos/administración & dosificación , Animales , Enfermedades de los Perros/prevención & control , Quimioterapia Combinada , Femenino , Histerectomía/veterinaria , Ketamina/administración & dosificación , Ketamina/efectos adversos , Morfina/administración & dosificación , Morfina/efectos adversos , Ovariectomía/veterinaria , Dolor Postoperatorio/prevención & control , Dolor Postoperatorio/veterinaria , Estereoisomerismo
11.
Clin J Pain ; 30(6): 490-500, 2014 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-24281290

RESUMEN

OBJECTIVES: Persistent postsurgical pain (PPP) after thoracotomy effect 50% to 80%. Nerve damage and central sensitization involving NDMDAr activation may play an important role. This study evaluates the efficacy of adding intravenous (IV) or epidural ketamine to thoracic epidural analgesia (TEA) after thoracotomy. MATERIALS AND METHODS: Double-blind randomized study on patients undergoing thoracotomy allocated to one of the following: group Kiv (IV racemic ketamine 0.5 mg/kg preincisional +0.25 mg/kg/h for 48 h), group Kep (epidural racemic ketamine 0.5 mg/kg preincisional +0.25 mg/kg/h for 48 h), or group S (saline). Postoperative analgesia was ensured by TEA with ropivacaine and fentanyl. Pain visual analog scales (VAS), Neuropathic Pain Symptom Inventory, Catastrophizing Scale, and Quantitative Sensory Testing, measuring both the peri-incisional and distant hyperalgesia area, were conducted preoperatively and postoperatively until 6 months. Plasma ketamine levels and stability of the analgesic solutions were analyzed. RESULTS: A total of 104 patients were included. PPP incidence was 20% at 6 months. Pain scores on coughing were significantly lower in Kiv and Kep than in S at 24 and 72 hours, but there were no differences afterwards. There were no significant differences in pain at rest, Neuropathic Pain Symptom Inventory, and Catastrophizing Scale, or in the area of mechanical allodynia at any time. Adverse effects were mild. Plasma ketamine levels did not differ significantly between groups. Analgesic solutions were stable. CONCLUSIONS: Adding epidural or IV racemic ketamine to TEA after thoracotomy did not lead to any reduction in PPP or allodynia. Epidural administration produced similar plasma ketamine levels to the IV route.


Asunto(s)
Analgesia Epidural , Analgésicos/uso terapéutico , Dolor Crónico/tratamiento farmacológico , Ketamina/uso terapéutico , Dolor Postoperatorio/tratamiento farmacológico , Toracotomía/efectos adversos , Enfermedad Aguda , Administración Intravenosa/efectos adversos , Adulto , Analgesia Epidural/efectos adversos , Analgésicos/efectos adversos , Analgésicos/sangre , Dolor Crónico/epidemiología , Dolor Crónico/etiología , Dolor Crónico/fisiopatología , Tos/fisiopatología , Método Doble Ciego , Femenino , Humanos , Hiperalgesia/tratamiento farmacológico , Hiperalgesia/epidemiología , Hiperalgesia/etiología , Hiperalgesia/fisiopatología , Incidencia , Ketamina/efectos adversos , Ketamina/sangre , Masculino , Persona de Mediana Edad , Manejo del Dolor/métodos , Dimensión del Dolor , Dolor Postoperatorio/epidemiología , Dolor Postoperatorio/etiología , Dolor Postoperatorio/fisiopatología , Tórax , Resultado del Tratamiento
14.
Clin J Pain ; 28(4): 318-23, 2012 May.
Artículo en Inglés | MEDLINE | ID: mdl-22001670

RESUMEN

OBJECTIVES: Von Frey monofilaments (VFM) and Electronic von Frey are used as quantitative sensory testing to explore mechanical hyperalgesia. The aim of the study was to determine VFM and Electronic von Frey reproducibility and the time required for testing undamaged areas in volunteers and surgical in-hospital patients. METHODS: Prospective study in 2 groups of individuals without neurological disorders and not receiving treatments that alter sensorial response. Group 1 was formed by 30 healthy volunteers and group 2 by 28 patients after knee arthroplasty who received unilateral femoral block as postoperative analgesia. Testing was performed by 2 trained investigators in the forearm and abdominal wall and repeated 24 hours later. Pain threshold was determined as the VMF or the pressure rate applied with the Electronic von Frey referred to as unpleasant. The time used in each test was measured. Intraobserver and interobserver reproducibility were analyzed by means of Kappa and Lin coefficients. RESULTS: Intraobserver and interobserver reproducibility for VFM was only fair or moderate in both groups (Kappa<0.6). Intraobserver reproducibility for Electronic von Frey was good in Group 1 (Lin 0.61 to 0.8) and almost perfect in Group 2 (Lin>0.8). No differences were found between the 2 tested areas. Time used was 6.03 and 3.16 minutes for VFM and Electronic von Frey, respectively. DISCUSSION: Exploration of mechanical allodynia in postoperative patients requires rapid and reliable quantitative sensory testing. Electronic von Frey was more reliable and rapid than VFM in exploring mechanical pain thresholds in undamaged areas in volunteers and patients. Further studies are required to confirm whether these results can be extrapolated to areas affected by surgery.


Asunto(s)
Electrónica , Hiperalgesia/fisiopatología , Dimensión del Dolor/métodos , Umbral del Dolor/fisiología , Dolor Postoperatorio/diagnóstico , Dolor Postoperatorio/fisiopatología , Adulto , Anciano , Anciano de 80 o más Años , Artroplastia de Reemplazo de Rodilla/efectos adversos , Femenino , Humanos , Hiperalgesia/diagnóstico , Masculino , Estimulación Física , Estudios Prospectivos , Reproducibilidad de los Resultados
15.
Med Clin (Barc) ; 139 Suppl 2: 46-50, 2012 Oct.
Artículo en Español | MEDLINE | ID: mdl-23498073

RESUMEN

Because of the characteristics of direct oral anticoagulants (DOA), the lack of an antidote to completely reverse their anticoagulant effects, the absence of standardization in monitoring of their effects, and limited experience of their use, specific recommendations for their management in the perioperative period or in emergencies are required. In elective surgery, in patients with normal renal function and low hemorrhagic/ thrombotic risk, DOA should be withdrawn 2 days before the intervention; when the hemorrhagic/ thrombotic risk is higher, bridge therapy with a low molecular weight hepatin beginning 5 days before the intervention is proposed as an alternative. In emergency surgery, systematic administration of hemostatic drugs as prophylaxis is not recommended. In DOA-related acute hemorrhage, administration of prothrombin complex concentrate, fresh plasma or factor VIIa should be evaluated, and general measures to control bleeding should be implemented.


Asunto(s)
Anticoagulantes/efectos adversos , Pérdida de Sangre Quirúrgica/prevención & control , Atención Perioperativa/métodos , Hemorragia Posoperatoria/prevención & control , Tromboembolia Venosa/prevención & control , Privación de Tratamiento , Administración Oral , Anticoagulantes/uso terapéutico , Bencimidazoles/efectos adversos , Bencimidazoles/uso terapéutico , Dabigatrán , Humanos , Morfolinas/efectos adversos , Morfolinas/uso terapéutico , Hemorragia Posoperatoria/inducido químicamente , Guías de Práctica Clínica como Asunto , Pirazoles/efectos adversos , Pirazoles/uso terapéutico , Piridonas/efectos adversos , Piridonas/uso terapéutico , Rivaroxabán , Tiofenos/efectos adversos , Tiofenos/uso terapéutico , beta-Alanina/efectos adversos , beta-Alanina/análogos & derivados , beta-Alanina/uso terapéutico
16.
J Clin Anesth ; 21(1): 30-7, 2009 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-19232938

RESUMEN

STUDY OBJECTIVE: To describe the characteristics of anesthetic and postoperative care applied in urologic surgery. DESIGN: Prospective, cross-sectional survey. SETTING: 131 authorized public and private hospitals in Catalonia, Spain. MEASUREMENTS: Data were collected from a representative sample of 23,136 patients and all questionnaires related to urologic surgery were analyzed. MAIN RESULTS: Data included patient characteristics, anesthetic techniques, and type of procedure. Eighty-five hospitals performed urologic surgery and 75.4% of activity took place in public hospitals. The median age of patients was 61 years and 87.3% were men. Preoperative physical status was poorer than in the rest of the surgical population. Surgery was elective in 93.2% of the cases, and the most frequent procedure was transurethral resection of bladder tissue (25.6%). The median duration of anesthesia was 60 minutes, and 9.7% of patients required postoperative admission to an intensive care unit. Regional anesthesia, especially subarachnoid block, was the most frequently used anesthetic technique. CONCLUSIONS: The older age and poor physical status of urology patients make high demands on anesthetic resources and must be considered in the organization of services and training programs.


Asunto(s)
Anestesia/métodos , Cuidados Posoperatorios/métodos , Procedimientos Quirúrgicos Urológicos/métodos , Adolescente , Adulto , Factores de Edad , Anciano , Anciano de 80 o más Años , Anestesia/estadística & datos numéricos , Anestesia de Conducción/métodos , Anestesia de Conducción/estadística & datos numéricos , Niño , Preescolar , Estudios Transversales , Procedimientos Quirúrgicos Electivos/métodos , Procedimientos Quirúrgicos Electivos/estadística & datos numéricos , Femenino , Hospitales Privados/estadística & datos numéricos , Hospitales Públicos/estadística & datos numéricos , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , España/epidemiología , Encuestas y Cuestionarios , Procedimientos Quirúrgicos Urológicos/estadística & datos numéricos , Adulto Joven
17.
Reg Anesth Pain Med ; 33(3): 211-6, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-18433671

RESUMEN

BACKGROUND AND OBJECTIVES: Damage to peripheral nerves provokes chronic neuropathic pain that lasts beyond the duration of the nerve injury. The presence of pain signs have been reported in areas other than those attributed to the injured nerve, i.e., in contralateral regions. We evaluated the presence, magnitude, and chronology of mechanical and cold allodynia in the contralateral paw of rats undergoing unilateral ligation of the L5 and L6 spinal nerves. METHODS: Twenty-three male Sprague-Dawley rats underwent spinal nerve ligation of the left L5 and L6 spinal nerves (SNL group) and 7 rats received a sham surgery without nerve ligation (sham group). Signs of mechanical allodynia as assessed with von Frey filaments, and cold allodynia as assessed with the acetone drop test, were studied before surgery and throughout 21 postoperative days. Responses of ipsilateral and contralateral paws of the SNL group were compared between themselves and with those in the sham group. RESULTS: Rats in the SNL group developed mechanical and cold allodynia responses in the ipsilateral paw, and also in the contralateral paw. Allodynia in the contralateral paw appeared later, becoming statistically significant on day 10 after surgery for mechanical allodynia and on day 21 for cold allodynia as compared with the sham group. Contralateral pain was of a lower intensity than on the ipsilateral side. CONCLUSIONS: After L5 and L6 spinal nerve ligation, rats developed mechanical and cold allodynia in the contralateral paw, suggesting extraterritorial development of neuropathic signs. This finding has implications for future study design and therapeutic approaches.


Asunto(s)
Neuralgia/fisiopatología , Nervios Espinales/fisiopatología , Animales , Frío , Modelos Animales de Enfermedad , Ligadura , Masculino , Estimulación Física , Ratas , Ratas Sprague-Dawley , Nervios Espinales/lesiones , Factores de Tiempo
18.
Can J Anaesth ; 53(6): 591-4, 2006 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-16738294

RESUMEN

PURPOSE: This report describes treatment with epidural dextran-40 and paramethasone injection of postural headache resulting from spontaneous intracranial hypotension in a pregnant patient. CLINICAL FEATURES: A 39-yr-old pregnant woman consulted the pain clinic for the assessment of a debilitating postural headache which was non-responsive to conventional analgesic treatment. Clinical findings and cranial magnetic resonance imaging indicated the diagnosis of spontaneous intracranial hypotension syndrome. Treatment with an epidural blood patch was not undertaken for several reasons. A lumbar epidural injection with dextran-40 and paramethasone led to a significant improvement in the symptoms and allowed a progressive discontinuation of adjuvant treatment with oral steroids, with complete resolution of symptoms. CONCLUSION: We report a case of spontaneous intracranial hypotension in a pregnant patient successfully treated by epidural injection of dextran-40 and paramethasone, with adjuvant oral steroid therapy. Clinical trials are warranted to establish the efficacy of this treatment as an alternative to the epidural blood patch administration.


Asunto(s)
Analgesia Epidural , Antiinflamatorios no Esteroideos/administración & dosificación , Antiinflamatorios no Esteroideos/uso terapéutico , Dextranos/administración & dosificación , Dextranos/uso terapéutico , Cefalea/tratamiento farmacológico , Hipotensión Intracraneal/tratamiento farmacológico , Parametasona/administración & dosificación , Parametasona/uso terapéutico , Sustitutos del Plasma/administración & dosificación , Sustitutos del Plasma/uso terapéutico , Adulto , Femenino , Cefalea/etiología , Cefalea/patología , Humanos , Hipotensión Intracraneal/complicaciones , Hipotensión Intracraneal/patología , Imagen por Resonancia Magnética , Embarazo
19.
Med Clin (Barc) ; 126 Suppl 2: 19-26, 2006 May 24.
Artículo en Español | MEDLINE | ID: mdl-16759601

RESUMEN

BACKGROUND AND OBJECTIVE: The aim of this arm of the ANESCAT 2003 study was to describe the temporal distribution and types of anesthesia used in Catalonia, Spain, in 2003, along with the associated human resources used. PATIENTS AND METHOD: Data were used from a survey of 23,136 anesthetic procedures collected on 14 randomly selected days in 2003 and an individual questionnaire was completed by 765 anesthesiologists working in Catalonia. RESULTS: Anesthesia practice was divided into that associated with surgery (78.4%), obstetrics (11.3%), and other nonsurgical procedures (10.4%). Of all anesthetic procedures performed, 84.3% took place in operating theaters and 7.0% in obstetric areas. Emergency procedures accounted for 20.3% of the total. Most procedures (71.2%) were undertaken within 08:00 and 16:00 h, and the lowest number of procedures performed on workdays took place on Fridays. The median duration of anesthesia was 60 minutes. The most common technique was regional anesthesia (41.4%), with spinal block being the most widely used. There were an estimated 12.5 anesthesiologists per 100,000 inhabitants, with a median (10th-90th percentile) age of 45 (34-57) years; women made up 47.2% of that group. The mean number of standard working hours was 46 hours per week and 65% of anesthesiologists also undertook on duty shifts. Anesthesiologists spent 77% of their time performing anesthesia and the remainder in postoperative recovery and critical care units and pain clinics. CONCLUSIONS: Emergency anesthesia represents 20% of the total workload and obstetrics and nonsurgical procedures another 20%. The use of regional anesthesia was very widespread. The population density of anesthesiologists is comparable to that of other European countries, but with a higher proportion of women.


Asunto(s)
Anestesia/estadística & datos numéricos , Anestesiología/estadística & datos numéricos , Encuestas de Atención de la Salud , Fuerza Laboral en Salud/estadística & datos numéricos , Pautas de la Práctica en Medicina/estadística & datos numéricos , Práctica Profesional/estadística & datos numéricos , Adulto , Anciano , Anestesia/métodos , Anestesia Obstétrica/métodos , Anestesia Obstétrica/normas , Anestesia Obstétrica/estadística & datos numéricos , Citas y Horarios , Sedación Consciente/estadística & datos numéricos , Estudios Transversales , Urgencias Médicas , Femenino , Humanos , Masculino , Persona de Mediana Edad , Embarazo , Estudios Prospectivos , Muestreo , España , Procedimientos Quirúrgicos Operativos/estadística & datos numéricos , Encuestas y Cuestionarios , Factores de Tiempo , Carga de Trabajo/estadística & datos numéricos
20.
Med Clin (Barc) ; 126 Suppl 2: 3-12, 2006 May 24.
Artículo en Español | MEDLINE | ID: mdl-16759599

RESUMEN

BACKGROUND AND OBJECTIVE: The increasing workload in anesthesiology together with the shortage of anesthetists has led to worldwide concern within the specialty. In 2003, the Catalan Society of Anesthesiology, Critical Care and Pain Therapy undertook the ANESCAT survey to determine the anesthesia practice workload in Catalonia, Spain. PATIENTS AND METHOD: A set of 3 questionnaires was used to quantify anesthesia practice and resources. A sample size of 12,228 events was estimated to be necessary to be representative of the number of anesthetic procedures carried out in Catalonia annually. A prospective, cross-sectional survey was carried out on 14 randomly chosen days in 2003. Each hospital designated a coordinator responsible for ensuring that a questionnaire was filled in for each anesthetic procedure, to provide information about patient characteristics, anesthetic technique, and the intervention for which anesthesia was needed. RESULTS: All 131 public and private hospitals in which anesthetic procedures were carried out participated. The geographic distribution was as follows: Barcelona city, 54 (41.2%); rest of the province of Barcelona, 39 (29.8%); Tarragona, 15 (11.5%); Girona, 14 (10.7%), and Lleida, 9 (6.9%). A total of 23,136 questionnaires about anesthesia procedures were received; the number of questionnaires returned on the selected workdays varied by 1.85% and the percentage of incomplete returns was less than 5%. The number of individual anesthetists returning questionnaires for processing was 765. CONCLUSIONS: This large-scale study was possible thanks to a simple design and the strong motivation of a community of anesthesiologists. The results have provided an accurate picture of anesthesia practice within a specific geographical area. Such studies are necessary for introducing organizational changes and applying for additional resources.


Asunto(s)
Anestesia/estadística & datos numéricos , Anestesiología/estadística & datos numéricos , Encuestas de Atención de la Salud , Pautas de la Práctica en Medicina/estadística & datos numéricos , Distribución por Edad , Anestesia/métodos , Anestesiología/tendencias , Estudios Transversales , Demografía , Grupos Diagnósticos Relacionados , Encuestas de Atención de la Salud/métodos , Hospitales/estadística & datos numéricos , Humanos , Enfermeras Anestesistas/estadística & datos numéricos , Estudios Prospectivos , Reproducibilidad de los Resultados , Muestreo , Distribución por Sexo , Sociedades Médicas , España , Encuestas y Cuestionarios , Recursos Humanos , Carga de Trabajo
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