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1.
A new AMPK activator, GSK773, corrects fatty acid oxidation and differentiation defect in CPT2-deficient myotubes.
Hum Mol Genet;
27(19): 3417-3433, 2018 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30007356
2.
Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection.
Commun Biol;
4(1): 197, 2021 02 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33580154
3.
Homotrimerization Approach in the Design of Thrombospondin-1 Mimetic Peptides with Improved Potency in Triggering Regulated Cell Death of Cancer Cells.
J Med Chem;
62(17): 7656-7668, 2019 09 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31403795
4.
Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.
J Med Chem;
62(10): 5096-5110, 2019 05 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-31013427
5.
Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade.
Biochem J;
403(1): 139-48, 2007 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17147517
6.
Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver.
Diabetes;
54(5): 1331-9, 2005 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15855317
7.
Thrombospondin-1 Mimetic Agonist Peptides Induce Selective Death in Tumor Cells: Design, Synthesis, and Structure-Activity Relationship Studies.
J Med Chem;
59(18): 8412-21, 2016 09 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-27526615
8.
Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2).
J Med Chem;
59(23): 10738-10749, 2016 12 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27933945
9.
Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening.
J Med Chem;
59(11): 5356-67, 2016 06 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27167608
10.
The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 1: 5,6,11,11a-tetrahydro-1H-imidazo[1',5':1,6]pyrido[3,4-b]indole-1,3(2H)-dione analogues.
J Med Chem;
46(21): 4525-32, 2003 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-14521414
11.
The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione analogues.
J Med Chem;
46(21): 4533-42, 2003 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-14521415
12.
Discovery of Pyridones As Oral AMPK Direct Activators.
ACS Med Chem Lett;
4(7): 632-6, 2013 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900722
13.
Comparison of soluble guanylate cyclase stimulators and activators in models of cardiovascular disease associated with oxidative stress.
Front Pharmacol;
3: 128, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22783192
14.
Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine.
J Lipid Res;
47(6): 1281-8, 2006 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-16508037
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