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1.

Breast Cancer Patients Have Greatly Benefited from the Progress in Molecular Oncology.

Groner, Bernd L; Hynes, Nancy E.

PLoS Biol; 14(9): e2000314, 2016 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-27684370

2.

The histone deacetylases HDAC1 and HDAC2 are required for the growth and survival of renal carcinoma cells.

Kiweler, Nicole; Brill, Boris; Wirth, Matthias; Breuksch, Ines; Laguna, Teresa; Dietrich, Cornelia; Strand, Susanne; Schneider, Günter; Groner, Bernd; Butter, Falk; Heinzel, Thorsten; Brenner, Walburgis; Krämer, Oliver H.

Arch Toxicol; 92(7): 2227-2243, 2018 07.

Artículo en Inglés | MEDLINE | ID: mdl-29845424

3.

5-Lipoxygenase is a direct p53 target gene in humans.

Gilbert, Bianca; Ahmad, Khalil; Roos, Jessica; Lehmann, Christoph; Chiba, Tomohiro; Ulrich-Rückert, Sandra; Smeenk, Leonie; van Heeringen, Simon; Maier, Thorsten J; Groner, Bernd; Steinhilber, Dieter.

Biochim Biophys Acta; 1849(8): 1003-16, 2015 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-26070487

4.

Expression of the miR-302/367 cluster in glioblastoma cells suppresses tumorigenic gene expression patterns and abolishes transformation related phenotypes.

Yang, Chul Min; Chiba, Tomohiro; Brill, Boris; Delis, Natalia; von Manstein, Viktoria; Vafaizadeh, Vida; Oellerich, Thomas; Groner, Bernd.

Int J Cancer; 137(10): 2296-309, 2015 Nov 15.

Artículo en Inglés | MEDLINE | ID: mdl-25991553

5.

Endotoxin depletion of recombinant protein preparations through their preferential binding to histidine tags.

Mack, Laura; Brill, Boris; Delis, Natalia; Groner, Bernd.

Anal Biochem; 466: 83-8, 2014 Dec 01.

Artículo en Inglés | MEDLINE | ID: mdl-25172132

6.

Mammary epithelial reconstitution with gene-modified stem cells assigns roles to Stat5 in luminal alveolar cell fate decisions, differentiation, involution, and mammary tumor formation.

Vafaizadeh, Vida; Klemmt, Petra; Brendel, Christian; Weber, Kristoffer; Doebele, Carmen; Britt, Kara; Grez, Manuel; Fehse, Boris; Desriviéres, Sylvane; Groner, Bernd.

Stem Cells; 28(5): 928-38, 2010 May.

Artículo en Inglés | MEDLINE | ID: mdl-20235097

7.

Monomeric recombinant peptide aptamers are required for efficient intracellular uptake and target inhibition.

Borghouts, Corina; Kunz, Christian; Delis, Natalia; Groner, Bernd.

Mol Cancer Res; 6(2): 267-81, 2008 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-18314488

8.

Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation.

Perotti, Christian; Liu, Ruixuan; Parusel, Christine T; Böcher, Nadine; Schultz, Jörg; Bork, Peer; Pfitzner, Edith; Groner, Bernd; Shemanko, Carrie S.

Breast Cancer Res; 10(6): R94, 2008.

Artículo en Inglés | MEDLINE | ID: mdl-19014541

9.

Peptide aptamer libraries.

Borghouts, Corina; Kunz, Christian; Groner, Bernd.

Comb Chem High Throughput Screen; 11(2): 135-45, 2008 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-18336207

10.

Peptide aptamers with binding specificity for the intracellular domain of the ErbB2 receptor interfere with AKT signaling and sensitize breast cancer cells to Taxol.

Kunz, Christian; Borghouts, Corina; Buerger, Claudia; Groner, Bernd.

Mol Cancer Res; 4(12): 983-98, 2006 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-17189388

11.

Mammalian target of rapamycin regulates the growth of mammary epithelial cells through the inhibitor of deoxyribonucleic acid binding Id1 and their functional differentiation through Id2.

Jankiewicz, Marcin; Groner, Bernd; Desrivières, Sylvane.

Mol Endocrinol; 20(10): 2369-81, 2006 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-16772532

12.

Jak Stat signaling and cancer: Opportunities, benefits and side effects of targeted inhibition.

Groner, Bernd; von Manstein, Viktoria.

Mol Cell Endocrinol; 451: 1-14, 2017 08 15.

Artículo en Inglés | MEDLINE | ID: mdl-28576744

13.

Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine.

Valent, Peter; Groner, Bernd; Schumacher, Udo; Superti-Furga, Giulio; Busslinger, Meinrad; Kralovics, Robert; Zielinski, Christoph; Penninger, Josef M; Kerjaschki, Dontscho; Stingl, Georg; Smolen, Josef S; Valenta, Rudolf; Lassmann, Hans; Kovar, Heinrich; Jäger, Ulrich; Kornek, Gabriela; Müller, Markus; Sörgel, Fritz.

J Innate Immun; 8(2): 111-20, 2016.

Artículo en Inglés | MEDLINE | ID: mdl-26845587

14.

Overexpression and forced activation of stat5 in mammary gland of transgenic mice promotes cellular proliferation, enhances differentiation, and delays postlactational apoptosis.

Iavnilovitch, Elena; Groner, Bernd; Barash, Itamar.

Mol Cancer Res; 1(1): 32-47, 2002 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-12496367

15.

The interaction of specific peptide aptamers with the DNA binding domain and the dimerization domain of the transcription factor Stat3 inhibits transactivation and induces apoptosis in tumor cells.

Nagel-Wolfrum, Kerstin; Buerger, Claudia; Wittig, Ilka; Butz, Karin; Hoppe-Seyler, Felix; Groner, Bernd.

Mol Cancer Res; 2(3): 170-82, 2004 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-15037656

16.

Signal transducer and activator of transcription 5 (STAT5), a crucial regulator of immune and cancer cells.

Wittig, Ilka; Groner, Bernd.

Curr Drug Targets Immune Endocr Metabol Disord; 5(4): 449-63, 2005 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-16375697

17.

Therapeutic antibodies.

Groner, Bernd; Hartmann, Cord; Wels, Winfried.

Curr Mol Med; 4(5): 539-47, 2004 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-15267225

18.

Stat5 Exerts Distinct, Vital Functions in the Cytoplasm and Nucleus of Bcr-Abl+ K562 and Jak2(V617F)+ HEL Leukemia Cells.

Weber, Axel; Borghouts, Corina; Brendel, Christian; Moriggl, Richard; Delis, Natalia; Brill, Boris; Vafaizadeh, Vida; Groner, Bernd.

Cancers (Basel); 7(1): 503-37, 2015 Mar 19.

Artículo en Inglés | MEDLINE | ID: mdl-25809097

19.

Improving Drug Penetrability with iRGD Leverages the Therapeutic Response to Sorafenib and Doxorubicin in Hepatocellular Carcinoma.

Schmithals, Christian; Köberle, Verena; Korkusuz, Hüdayi; Pleli, Thomas; Kakoschky, Bianca; Augusto, Eduardo Alonso; Ibrahim, Ahmed Atef; Arencibia, Jose M; Vafaizadeh, Vida; Groner, Bernd; Korf, Horst-Werner; Kronenberger, Bernd; Zeuzem, Stefan; Vogl, Thomas J; Waidmann, Oliver; Piiper, Albrecht.

Cancer Res; 75(15): 3147-54, 2015 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-26239478

20.

Bifunctional recombinant proteins in cancer therapy: cell penetrating peptide aptamers as inhibitors of growth factor signaling.

Buerger, Claudia; Groner, Bernd.

J Cancer Res Clin Oncol; 129(12): 669-75, 2003 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-13680379

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