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1.

17q21 Variants Disturb Mucosal Host Defense in Childhood Asthma.

Jakwerth, Constanze A; Weckmann, Markus; Illi, Sabina; Charles, Helen; Zissler, Ulrich M; Oelsner, Madlen; Guerth, Ferdinand; Omony, Jimmy; Nemani, Sai Sneha Priya; Grychtol, Ruth; Dittrich, Anna-Maria; Skevaki, Chrysanthi; Foth, Svenja; Weber, Stefanie; Alejandre Alcazar, Miguel A; van Koningsbruggen-Rietschel, Silke; Brock, Robert; Blau, Samira; Hansen, Gesine; Bahmer, Thomas; Rabe, Klaus F; Brinkmann, Folke; Kopp, Matthias Volkmar; Chaker, Adam M; Schaub, Bianca; von Mutius, Erika; Schmidt-Weber, Carsten B.

Am J Respir Crit Care Med; 209(8): 947-959, 2024 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-38064241

2.

Validation of the Asthma Severity Scoring System (ASSESS) in the ALLIANCE Cohort.

Grychtol, Ruth; Riemann, Lennart; Gaedcke, Svenja; Liu, Bin; DeLuca, David; Förster, Reinhold; Maison, Nicole; Thiele, Dominik; Jakobs, Nikolas; Bahmer, Thomas; Meyer, Meike; Foth, Svenja; Weber, Stefanie; Rietschel, Ernst; Rabe, Klaus F; Kopp, Matthias V; von Mutius, Erika; Dittrich, Anna-Maria; Hansen, Gesine.

J Allergy Clin Immunol; 151(6): 1525-1535.e4, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-36804993

3.

Tracheostomy decannulation in children: a proposal for a structured approach on behalf of the working group chronic respiratory insufficiency within the German-speaking society of pediatric pulmonology.

Böschen, Eicke; Wendt, Anke; Müller-Stöver, Sarah; Piechnik, Lydia; Fuchs, Hans; Lund, Madeleine; Steindor, Mathis; Große-Onnebrink, Jörg; Keßler, Christina; Grychtol, Ruth; Rothoeft, Tobias; Bieli, Christian; van Egmond-Fröhlich, Andreas; Stehling, Florian.

Eur J Pediatr; 182(7): 2999-3006, 2023 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-37121990

4.

Quality Control of Nitrogen Multiple Breath Washout in a Multicenter Pediatric Asthma Study.

Nitsche, Catharina; Frauchiger, Bettina Sarah; Thiele, Dominik; Oestreich, Marc-Alexander; Husstedt, Berrit Liselotte; Grychtol, Ruth Margarethe; Maison, Nicole; Foth, Svenja; Meyer, Meike; Jakobs, Nikolas; Bahmer, Thomas; Hansen, Gesine; von Mutius, Erika; Kopp, Matthias.

Klin Padiatr; 235(2): 66-74, 2023 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-36657454

5.

T2-high asthma phenotypes across lifespan.

Maison, Nicole; Omony, Jimmy; Illi, Sabina; Thiele, Dominik; Skevaki, Chrysanthi; Dittrich, Anna-Maria; Bahmer, Thomas; Rabe, Klaus Friedrich; Weckmann, Markus; Happle, Christine; Schaub, Bianca; Meyer, Meike; Foth, Svenja; Rietschel, Ernst; Renz, Harald; Hansen, Gesine; Kopp, Matthias Volkmar; von Mutius, Erika; Grychtol, Ruth; Fuchs, Oliver; Roesler, Barbara; Welchering, Nils; Kohistani-Greif, Naschla; Kurz, Johanna; Landgraf-Rauf, Katja; Laubhahn, Kristina; Liebl, Claudia; Ege, Markus; Hose, Alexander; Zeitlmann, Esther; Berbig, Mira; Marzi, Carola; Schauberger, Christina; Zissler, Ulrich; Schmidt-Weber, Carsten; Ricklefs, Isabell; Diekmann, Gesa; Liboschik, Lena; Voigt, Gesche; Sultansei, Laila; Nissen, Gyde; König, Inke R; Kirsten, Anne-Marie; Pedersen, Frauke; Watz, Henrik; Waschki, Benjamin; Herzmann, Christian; Abdo, Mustafa; Biller, Heike; Gaede, Karoline I.

Eur Respir J; 60(3)2022 09.

Artículo en Inglés | MEDLINE | ID: mdl-35210326

6.

IgA⁺ memory B-cells are significantly increased in patients with asthma and small airway dysfunction.

Habener, Anika; Grychtol, Ruth; Gaedcke, Svenja; DeLuca, David; Dittrich, Anna-Maria; Happle, Christine; Abdo, Mustafa; Watz, Henrik; Pedersen, Frauke; König, Inke Regina; Thiele, Dominik; Kopp, Matthias Volkmar; von Mutius, Erika; Bahmer, Thomas; Rabe, Klaus Friedrich; Meyer-Bahlburg, Almut; Hansen, Gesine; Fuchs, Oliver; Roesler, Barbara; Welchering, Nils; Kohistani-Greif, Naschla; Kurz, Johanna; Landgraf-Rauf, Katja; Laubhahn, Kristina; Maison, Nicole; Liebl, Claudia; Schaub, Bianca; Ege, Markus; Illi, Sabina; Hose, Alexander; Zeitlmann, Esther; Berbig, Mira; Marzi, Carola; Schauberger, Christina; Zissler, Ulrich; Schmidt-Weber, Carsten; Ricklefs, Isabell; Diekmann, Gesa; Liboschik, Lena; Voigt, Gesche; Sultansei, Laila; Weckmann, Markus; Nissen, Gyde; Kirsten, Anne-Marie; Waschki, Benjamin; Herzmann, Christian; Biller, Heike; Gaede, Karoline I; Bovermann, Xenia; Steinmetz, Alena.

Eur Respir J; 60(5)2022 11.

Artículo en Inglés | MEDLINE | ID: mdl-35595320

7.

Complete Tracheal Ring Deformity, Recurrent Pneumothoraces and Pleuropulmonary Blastoma in a Child: Coincidence or Common Genetic Cause?

Thiemann, Inga; Hoppen, Thomas; Laur, Martin; Ohlert, Manuel; Lobitz, Stephan; Schwerk, Nicolaus; Dingemann, Jens; Länger, Florian; Grychtol, Ruth Margarethe; Nüßlein, Thomas.

Klin Padiatr; 234(5): 311-313, 2022 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-35114704

8.

Regulatory B cells control airway hyperreactivity and lung remodeling in a murine asthma model.

Habener, Anika; Happle, Christine; Grychtol, Ruth; Skuljec, Jelena; Busse, Mandy; Dalüge, Kathleen; Obernolte, Helena; Sewald, Katherina; Braun, Armin; Meyer-Bahlburg, Almut; Hansen, Gesine.

J Allergy Clin Immunol; 147(6): 2281-2294.e7, 2021 06.

Artículo en Inglés | MEDLINE | ID: mdl-33249168

9.

IL-17 regulates DC migration to the peribronchial LNs and allergen presentation in experimental allergic asthma.

Jirmo, Adan Chari; Busse, Mandy; Happle, Christine; Skuljec, Jelena; Dalüge, Kathleen; Habener, Anika; Grychtol, Ruth; DeLuca, David S; Breiholz, Oliver D; Prinz, Immo; Hansen, Gesine.

Eur J Immunol; 50(7): 1019-1033, 2020 07.

Artículo en Inglés | MEDLINE | ID: mdl-32142593

10.

Improved protocol for simultaneous analysis of leukocyte subsets and epithelial cells from murine and human lung.

Happle, Christine; Meyer-Decking, Lena; Dreier, Anika; Wetzke, Martin; Gläsener, Stephanie; Grychtol, Ruth; Braubach, Peter; Jablonka, Alexandra; Haid, Sibylle; Jirmo, Adan Chari; Habener, Anika; Skuljec, Jelena; Hansen, Gesine.

Exp Lung Res; 44(3): 127-136, 2018 04.

Artículo en Inglés | MEDLINE | ID: mdl-29677457

11.

The role of sleep diagnostics and non-invasive ventilation in children with spinal muscular atrophy.

Grychtol, Ruth; Abel, Francois; Fitzgerald, Dominic A.

Paediatr Respir Rev; 28: 18-25, 2018 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-30396824

12.

Reduced PRF1 enhancer methylation in children with a history of severe RSV bronchiolitis in infancy: an association study.

Elgizouli, Magdeldin; Logan, Chad; Grychtol, Ruth; Rothenbacher, Dietrich; Nieters, Alexandra; Heinzmann, Andrea.

BMC Pediatr; 17(1): 65, 2017 03 03.

Artículo en Inglés | MEDLINE | ID: mdl-28253869

13.

Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33.

Castanhinha, Susana; Sherburn, Rebekah; Walker, Simone; Gupta, Atul; Bossley, Cara J; Buckley, James; Ullmann, Nicola; Grychtol, Ruth; Campbell, Gaynor; Maglione, Marco; Koo, Sergio; Fleming, Louise; Gregory, Lisa; Snelgrove, Robert J; Bush, Andrew; Lloyd, Clare M; Saglani, Sejal.

J Allergy Clin Immunol; 136(2): 312-22.e7, 2015 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-25746970

14.

Single cell RNA sequencing reveals distinct clusters of Irf8-expressing pulmonary conventional dendritic cells.

Jirmo, Adan Chari; Grychtol, Ruth; Gaedcke, Svenja; Liu, Bin; DeStefano, Stephanie; Happle, Christine; Halle, Olga; Monteiro, Joao T; Habener, Anika; Breiholz, Oliver D; DeLuca, David; Hansen, Gesine.

Front Immunol; 14: 1127485, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37251386

15.

Timing of Blood Sample Processing Affects the Transcriptomic and Epigenomic Profiles in CD4⁺ T-cells of Atopic Subjects.

Alhamdan, Fahd; Laubhahn, Kristina; Happle, Christine; Habener, Anika; Jirmo, Adan C; Thölken, Clemens; Conca, Raffaele; Chung, Ho-Ryun; Hansen, Gesine; Potaczek, Daniel P; Schaub, Bianca; Grychtol, Ruth; Garn, Holger.

Cells; 11(19)2022 09 22.

Artículo en Inglés | MEDLINE | ID: mdl-36230920

16.

In vitro neutrophil migration is associated with inhaled corticosteroid treatment and serum cytokines in pediatric asthma.

Lemmel, Solveig; Weckmann, Markus; Wohlers, Anna; Jirmo, Adan Chari; Grychtol, Ruth; Ricklefs, Isabell; Nissen, Gyde; Bachmann, Anna; Singh, Shantanu; Caicedo, Juan; Bahmer, Thomas; Hansen, Gesine; Von Mutius, Erika; Rabe, Klaus F; Fuchs, Oliver; Dittrich, Anna-Maria; Schaub, Bianca; Happle, Christine; Carpenter, Anne E; Kopp, Matthias Volkmar; Becker, Tim.

Front Pharmacol; 13: 1021317, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-36304163

17.

Impact of imposed social isolation and use of face masks on asthma course and mental health in pediatric and adult patients with recurrent wheeze and asthma.

Maison, Nicole; Herbrüggen, Heidrun; Schaub, Bianca; Schauberger, Christina; Foth, Svenja; Grychtol, Ruth; Abdo, Mustafa; Watz, Henrik; Nikolaizik, Wilfried; Rabe, Klaus F; Kopp, Matthias V; Hansen, Gesine; von Mutius, Erika; Bahmer, Thomas; Omony, Jimmy.

Allergy Asthma Clin Immunol; 17(1): 93, 2021 Sep 16.

Artículo en Inglés | MEDLINE | ID: mdl-34530911

18.

Differential expression patterns of glycosphingolipids and C-type lectin receptors on immune cells in absence of functional regulatory T cells.

Jirmo, Adan C; Rossdam, Charlotte; Grychtol, Ruth; Happle, Christine; Gerardy-Schahn, Rita; Buettner, Falk F R; Hansen, Gesine.

Immun Inflamm Dis; 8(4): 512-522, 2020 12.

Artículo en Inglés | MEDLINE | ID: mdl-32737949

19.

FoxP3 deficiency causes no inflammation or neurodegeneration in the murine brain.

Gingele, Stefan; Pul, Refik; Sardari, Maryam; Borbor, Mina; Henkel, Florian; Moellenkamp, Thiemo M; Gudi, Viktoria; Happle, Christine; Grychtol, Ruth; Habener, Anika; Hansen, Gesine; Hermann, Dirk M; Stangel, Martin; Kleinschnitz, Christoph; Skuljec, Jelena.

J Neuroimmunol; 342: 577216, 2020 Mar 18.

Artículo en Inglés | MEDLINE | ID: mdl-32199198

20.

Use of non-invasive ventilation in cerebral palsy.

Grychtol, Ruth; Chan, Elaine Y.

Arch Dis Child; 103(12): 1170-1177, 2018 12.

Artículo en Inglés | MEDLINE | ID: mdl-29886412

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