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OBJECTIVE: Hearing loss (HL) is common in patients with chronic renal failure (CRF), but its cause is controversial. The aim of this study was to determine the effect of CRF on the bone density of the otic capsule using densitometric measurements with MDCT and to evaluate the relationship between changes in the otic capsule density and HL in patients with CRF. MATERIALS AND METHODS: The study included 34 patients with nonsyndromic CRF undergoing hemodialysis and 35 healthy control subjects. A CT was obtained, for a variety of reasons, in control subjects who did not have CRF or HL, but patients with trauma and infection were excluded. Control subjects were chosen on the basis of a normal CT and pure tone audiometry findings. Densitometric measurements were made using CT in the region anterior to the oval window and anterior to the internal auditory canal. These measurements were compared between patients and control subjects. Pure tone audiometry was performed to detect HL. The average levels of parathyroid hormone in the previous 6 months and the duration of hemodialysis in patients were documented. The association between the levels of parathyroid hormone, the duration of hemodialysis, and the region-of-interest density values in the patient groups were evaluated using the Pearson correlation coefficient. RESULTS: HL was found in 40 of 68 ears (58.8%) in the patient group. A significant difference in the otic capsule density was found between the ears with and without HL. There was a strong negative correlation between the parathyroid hormone level and the densitometric measurement of the otic capsule. CONCLUSION: There is osseous remodeling of the otic capsule in CRF with loss of bone density, and this is associated with HL in CRF.
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Cóclea/diagnóstico por imagen , Pérdida Auditiva/diagnóstico por imagen , Pérdida Auditiva/etiología , Fallo Renal Crónico/complicaciones , Tomografía Computarizada por Rayos X/métodos , Absorciometría de Fotón , Adulto , Audiometría de Tonos Puros , Densidad Ósea , Remodelación Ósea , Estudios de Casos y Controles , Femenino , Humanos , Fallo Renal Crónico/terapia , Masculino , Persona de Mediana Edad , Diálisis Renal , Factores de RiesgoRESUMEN
Although alveolar echinococcosis (AE) can cause a serious disease with high mortality and morbidity similar to malign neoplasms. A 62-year-old woman admitted to a hospital located in Sivas, Turkey, with the complaints of fatigue and right upper abdominal pain. On contrast abdominal CT, a 54×70×45 mm sized cystic lesion was detected in the left lobe of the liver that was seen to extend to the posterior mediastinum and invade the diaphragm, esophagus, and pericardium. The cystic lesion was seen to be occluding the inferior vena cava and left hepatic vein at the level where the hepatic veins poured into the inferior vena cava. Bilateral pleural effusion was also detected. We discussed this secondary Budd-Chiari Syndrome (BCS) case, resulting from the AE occlusion of the left hepatic vein and inferior vena cava, in light of the information in literature.
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Síndrome de Budd-Chiari/etiología , Equinococosis Hepática/complicaciones , Animales , Antihelmínticos/uso terapéutico , Síndrome de Budd-Chiari/tratamiento farmacológico , Síndrome de Budd-Chiari/parasitología , Equinococosis , Equinococosis Hepática/tratamiento farmacológico , Equinococosis Hepática/parasitología , Echinococcus multilocularis/aislamiento & purificación , Femenino , Humanos , Persona de Mediana EdadRESUMEN
BACKGROUND: Various visual semi-quantitative staging systems based on high-resolution computed tomography are used to evaluate inflammatory rheumatologic disease-associated interstitial lung disease. We aimed in this retrospective study to evaluate whether tomographic fibrosis score, a new visual semi-quantitative staging system, was a predictor of mortality and the relationship between tomographic fibrosis score and respiratory function tests in patients with systemic sclerosis-associ- ated interstitial lung disease. METHODS: The patients who have been followed up at a single-center rheumatology clinic for the last 5 years and met the American College of Rheumatology / European League Against Rheumatism (ACR-EULAR) 2013 systemic sclerosis classification criteria were included in the study. Clinical data were obtained retrospectively from patient records, including patients' characteristics, pulmonary function test (forced vital capacity), diffusing capacity of the lung for carbon monoxide test, high-reso- lution computed tomography results, medication history, and serological test results. High-resolution computed tomography of the patients diagnosed with interstitial lung disease were assessed for the study. The radiologists scored the extent of parenchymal abnormalities (ground glass opacification, reticulation, honeycombing, and consolidation) and calculated tomographic fibrosis score and also traction bronchiectasis score for each patient. RESULTS: Fifty-two patients (46 female, median age 60 (Q1-Q3:47-66) years) were included in this study. The median disease duration, follow-up time, interstitial lung disease duration, and time from sys- temic sclerosis diagnosis to interstitial lung disease diagnosis were 80 (59-143) months, 78 (50-119) months, 63 (43-81) months, and 4 (0-58) months, respectively. The median tomographic fibrosis score and traction bronchiectasis score of the patients were 3.08% (1.33-8.06) and 0 (0-2), respectively. There was a moderate direct correlation between tomographic fibrosis score and traction bronchiectasis score (r = +0.472, P < .001). Additionally, there was a mod- erate inverse correlation between tomographic fibrosis score and diffusing capacity of the lung for carbon monoxide at diagnosis (r = -0.554, P = .011). During the follow-up period, 12 (23%) patients died. Kaplan-Meier Test (P = 0.009) and Cox regression analysis (B: 4.673, 95% confidence interval, 1.321-16.529, P = .017) revealed that tomographic fibrosis score ≥ 5% was associated with mortality. Multivariate analysis was not performed due to the small number of patients. CONCLUSION: An inverse relationship was found between tomographic fibrosis score and diffusing capacity of the lung for carbon monoxide at diagnosis. The odds ratio for mortality was 4.7 when tomographic fibrosis score was ≥5%. Tomographic fibrosis score may be useful for predicting mor- tality and respiratory function in patients with systemic sclerosis-associated interstitial lung disease.
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The aim of this study was to investigate the effects of systemically applied zoledronic acid (ZA) on osteoblastic bone formation and relapse in the rat sagittal suture after expansion. Eighteen 12-week-old male Wistar rats were divided into three groups. In groups 1 and 2, a saline solution was given subcutaneously after expansion and the retention period lasted for 14 and 7 days, respectively. In group 3, 0.1 mg of ZA was diluted with saline and given subcutaneously after expansion: the retention period lasted for 7 days. Computed tomography (CT) measurements were obtained at the start of the study (T1), after expansion (T2), after the retention period (T3), and after the follow-up period (T4). The amount of expansion and relapse and the density of the newly formed bone in the expansion area were measured. The mean bone density values in hounsfield unit (HU) of the newly formed bone were recorded using MX View Workstation. Data were analysed using the Kruskal-Wallis, Friedman, Wilcoxon, and Mann-Whitney U-tests. The results showed that there were significant differences between the groups in the density of newly formed bone after the retention period (P < 0.05). Statistically significant differences were observed when the relapse percentages were compared between the groups (P < 0.05). ZA stimulated bone formation and decreased the relapse ratio after expansion in the rat sagittal suture.
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Conservadores de la Densidad Ósea/farmacología , Suturas Craneales/efectos de los fármacos , Difosfonatos/farmacología , Imidazoles/farmacología , Osteogénesis/efectos de los fármacos , Hueso Parietal/efectos de los fármacos , Tomografía Computarizada por Rayos X/métodos , Animales , Densidad Ósea/efectos de los fármacos , Conservadores de la Densidad Ósea/administración & dosificación , Hilos Ortopédicos , Suturas Craneales/cirugía , Difosfonatos/administración & dosificación , Imidazoles/administración & dosificación , Inyecciones Subcutáneas , Masculino , Hueso Parietal/cirugía , Ratas , Ratas Wistar , Factores de Tiempo , Tracción/instrumentación , Tracción/métodos , Ácido ZoledrónicoRESUMEN
PURPOSE: The aim of this study was to evaluate the distribution and absorption of local anesthetic solutions in inferior alveolar nerve block using magnetic resonance imaging. MATERIALS AND METHODS: Forty healthy volunteers were divided into 4 groups and injected with 1.5 mL for inferior alveolar nerve block and 0.3 mL for lingual nerve block. The solutions used for the different groups were 2% lidocaine, 2% lidocaine with 0.125 mg/mL epinephrine, 4% articaine with 0.006 mg/mL epinephrine, and 4% articaine with 0.012 mg/mL epinephrine. All subjects had axial T2-weighted and fat-suppressed images at 0, 60, and 120 minutes after injection. The localization, area, and intensity (signal characteristics) of the solutions were analyzed and onset and duration times of the anesthesia were recorded. RESULTS: There were no significant differences between groups with regard to the intensity and area of the solutions at 0, 60, and 120 minutes after injection, but differences were found within each group. CONCLUSIONS: No between-group differences were found on magnetic resonance imaging in the distribution and absorption of lidocaine with or without epinephrine and articaine with 0.006 and 0.012 mg/mL epinephrine. All solutions were noticeably absorbed at 120 minutes after injection.
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Anestésicos Locales/farmacocinética , Imagen por Resonancia Magnética/métodos , Nervio Mandibular , Bloqueo Nervioso , Absorción , Anestesia Local , Anestésicos Locales/administración & dosificación , Carticaína/administración & dosificación , Carticaína/farmacocinética , Epinefrina/administración & dosificación , Epinefrina/farmacocinética , Femenino , Humanos , Aumento de la Imagen/métodos , Procesamiento de Imagen Asistido por Computador/métodos , Inyecciones/métodos , Lidocaína/administración & dosificación , Lidocaína/farmacocinética , Nervio Lingual/efectos de los fármacos , Labio/efectos de los fármacos , Masculino , Nervio Mandibular/efectos de los fármacos , Factores de Tiempo , Distribución Tisular , Lengua/efectos de los fármacos , Vasoconstrictores/administración & dosificación , Vasoconstrictores/farmacocinética , Adulto JovenRESUMEN
This study aimed to investigate the effect of chronic rhinosinusitis/nasal polyposis on the severity of COPD and to find out whether the 'united airway disease' hypothesis is valid for COPD. The study enrolled 90 patients diagnosed and staged according to criteria of an international guideline for diagnosis and management of COPD. The patients in stages I and II were classified as Group 1 and the patients in stages III and IV as Group 2. All the patients were questioned about the presence of major and minor criteria of sinusitis, underwent paranasal sinus computed tomography (PNS-CT) scans, and answered a questionnaire based on a quality of life test for sinusitis (SNOT-20). Sinusitis was present in 48 (53%) patients according to criteria of major and minor symptoms, and in 58 (64%) patients according to Lund-Mackay scoring system of PNS-CT. There was no significant difference in CT score between Group 1 and Group 2 (2.3 +/- 0.5 vs. 2.1 +/- 0.4, p > 0.05). However, the frequency of minor symptoms was greater in Group 2. SNOT-20 score was significantly higher in Group 2 than in Group 1 (28.7 +/- 1.7 and 22.2 +/- 1.9, respectively, p = 0.014). A significant correlation was determined between Lund-Mackay and SNOT-20 scores. The presence of CRS should be assessed in COPD patients, especially in those with severe disease. Further research is needed to disclose possible common immunopathological mechanisms in the pathogeneses of COPD and CRS.
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Pólipos Nasales/epidemiología , Enfermedad Pulmonar Obstructiva Crónica/epidemiología , Rinitis/epidemiología , Sinusitis/epidemiología , Enfermedad Crónica , Comorbilidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pólipos Nasales/diagnóstico , Pólipos Nasales/psicología , Prevalencia , Enfermedad Pulmonar Obstructiva Crónica/diagnóstico , Enfermedad Pulmonar Obstructiva Crónica/psicología , Calidad de Vida , Rinitis/diagnóstico , Rinitis/psicología , Índice de Severidad de la Enfermedad , Sinusitis/diagnóstico , Sinusitis/psicología , Encuestas y Cuestionarios , Tomografía Computarizada por Rayos XRESUMEN
INTRODUCTION: The aim of this experimental study was to evaluate the effects of systemically applied zoledronic acid on bone regeneration in response to expansion of the sagittal suture and relapse in rats. METHODS: Thirty-six male Wistar rats were divided into 3 groups. In the first and second groups, saline solution was given subcutaneously after expansion, and the retention periods lasted 14 and 7 days, respectively. In the third group, 0.1 mg of zoledronic acid was diluted with saline solution and given subcutaneously after expansion; the retention period lasted for 7 days. Expansion and relapse amounts were measured by using computed tomography. After the retention period, 6 rats from each group were killed for histologic and immunohistochemical assessments. The other 6 rats from each group were used for observation of the relapse. RESULTS: The histologic evaluation showed that, in groups 1 and 2, the numbers of osteoblasts were less than observed in group 3. When scores of staining intensity were compared, immunoreactivities were statistically significantly increased in group 3 compared with groups 2 and 1. Statistically significant differences were found when the relapse percentages were compared between the groups (P <0.05). The smallest relapse occurred in group 3. CONCLUSIONS: Zoledronic acid has positive effects on bone formation in the sagittal suture in response to expansion and decreases the relapse ratio after expansion in rats.
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Conservadores de la Densidad Ósea/farmacología , Regeneración Ósea/efectos de los fármacos , Suturas Craneales/efectos de los fármacos , Difosfonatos/farmacología , Imidazoles/farmacología , Osteogénesis/efectos de los fármacos , Animales , Conservadores de la Densidad Ósea/administración & dosificación , Difosfonatos/administración & dosificación , Imidazoles/administración & dosificación , Técnicas para Inmunoenzimas , Inyecciones Subcutáneas , Masculino , Osteoblastos/metabolismo , Osteocalcina/biosíntesis , Osteonectina/biosíntesis , Técnica de Expansión Palatina , Ratas , Ratas Wistar , Prevención Secundaria , Factor de Crecimiento Transformador beta/biosíntesis , Factor A de Crecimiento Endotelial Vascular/biosíntesis , Ácido ZoledrónicoRESUMEN
BACKGROUND: COVID-19 generally affects the lungs by causing pneumonic infiltration. Typical Computed Tomography (CT) findings are bilateral, multifocal, peripheral, and patchy ground-glass opacities. These CT findings can also be seen in drug toxicities. Rapid and accurate differential diagnosis of COVID-19 pneumonia from Chemotherapy-Induced Pulmonary Toxicity (CPT) is essential because the treatment strategies are different. In this case report, we define the clinical and lung CT findings of two cases of CPT mimicking COVID-19 pneumonia. CASE REPORTS: The first patient was a 39-year-old male who was under a 5-fluorouracil + folinicacid + oxaliplatin + panitumumab (FOLFOX) treatment of regimen because of metastatic rectal cancer. The second patient was a 53-year-old male with testicular seminoma who was treated with bleomycin, etoposide, and cisplatin (BEP) protocol. Both patients presented to the emergency department with increased dyspnea after chemotherapy. Thorax CT showed similar findings to COVID-19 pneumonia. On follow-up CTs, these findings disappeared with steroid treatment as well as withdrawal of the chemotherapeutic agents and this enabled us to make a differential diagnosis. Also, two consecutive COVID-19 real-time polymerase chain reaction tests were negative in both patients. CONCLUSION: When lung CT findings of the oncologic patients are similar to COVID-19 pneumonia, chemotherapy-induced pulmonary toxicity should also be considered in the differential diagnosis.
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COVID-19 , Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos , Adulto , Humanos , Pulmón/diagnóstico por imagen , Masculino , Persona de Mediana Edad , SARS-CoV-2 , Tomografía Computarizada por Rayos XRESUMEN
PURPOSE: The aim of this study was to evaluate the presence of probable diffused local anesthetic solution at and anesthesia of palatal tissues after buccal injection of 4% articaine hydrochloride (HCl) with 1:100,000 epinephrine or 1:200,000 epinephrine at the premolar and molar region. MATERIALS AND METHODS: Thirty volunteers received maxillary buccal injections of 4% articaine HCl with 1:100,000 epinephrine or 1:200,000 epinephrine bilaterally to the first premolar or first molar. Magnetic resonance images were obtained before and 5 minutes after local anesthetic injections, and a visual evaluation was done to determine the presence of local anesthetic solution at palatal tissues. Anesthesia of palatal tissues after buccal injection was assessed by needle-prick stimulation pain with a visual analog scale (VAS). The Kruskal-Wallis test was used for comparison of the VAS values. RESULTS: The visual evaluation of the magnetic resonance images did not show any signal change as an indicator of the presence of local anesthetic solution at the palatal region. Most of the volunteers described moderate or severe pain with needle-prick stimulation. The mean VAS score for needle-prick stimulation was 86.33 +/- 39.45 mm (1:100,000 epinephrine) and 87.0 +/- 36.28 mm (1:200,000 epinephrine) in the first premolar region and 57.20 +/- 46.69 mm (1:100,000 epinephrine) and 75.53 +/- 49.78 mm (1:200,000 epinephrine) in the molar region (P > .05). CONCLUSION: We could not establish the presence of anesthesia or 4% articaine HCl at the palatal tissues after buccal injection. Maxillary tooth removal without palatal injection requires further objective investigations.
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Anestésicos Locales/administración & dosificación , Carticaína/administración & dosificación , Hueso Paladar/efectos de los fármacos , Adulto , Diente Premolar , Epinefrina/administración & dosificación , Femenino , Humanos , Inyecciones , Imagen por Resonancia Magnética , Masculino , Diente Molar , Mucosa Bucal , Dimensión del Dolor , Hueso Paladar/anatomía & histología , Estimulación Física , Vasoconstrictores/administración & dosificación , Adulto JovenRESUMEN
PURPOSE: In this study, oxaprozin, a long-acting nonsteroidal anti-inflammatory drug, and naproxen sodium were compared in terms of their effects on edema, pain, and trismus after surgery for impacted mandibular third molars. MATERIALS AND METHODS: Thirty healthy patients with bilaterally impacted mandibular third molars were included in this randomized, cross-over, double-blind, placebo-controlled study. Patients were assigned randomly to 1 of 3 surgery groups and received postoperatively 1,200 mg oxaprozin, 550 mg naproxen sodium, or a placebo. Postoperative edema was measured with ultrasonography performed before and after surgery. Trismus was measured by comparison of preoperative and postoperative maximum interincisal mouth opening measurements by caliper. Pain was assessed by a visual analog scale (VAS) and by recording the number of rescue analgesic pills taken. RESULTS: After removal of impacted third molars, the patients administered oxaprozin and naproxen showed superior results over those given placebo in terms of pain parameters (P < .05), but these treatments had no statistically significant effect on facial swelling. Comparing the oxaprozin and naproxen groups, there were no differences in the mouth opening measurements, but naproxen showed a statistically superior effect over the placebo (P < .05). Although not statistically significant, oxaprozin showed a more pronounced effect in reducing trismus than did the placebo (P = .07). CONCLUSIONS: Administration of either oxaprozin or naproxen sodium during the postoperative period is effective and has similar effects in reducing pain but questionable benefit for the management of trismus. However, neither agent has clinical benefit in terms of reducing edema.
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Antiinflamatorios no Esteroideos/uso terapéutico , Antiinflamatorios/uso terapéutico , Tercer Molar/cirugía , Naproxeno/uso terapéutico , Propionatos/uso terapéutico , Diente Impactado/cirugía , Adolescente , Estudios Cruzados , Método Doble Ciego , Edema/prevención & control , Cara , Femenino , Humanos , Masculino , Mandíbula/fisiopatología , Oxaprozina , Dolor Postoperatorio/prevención & control , Placebos , Estudios Prospectivos , Rango del Movimiento Articular/fisiología , Trismo/prevención & control , Adulto JovenRESUMEN
A preventable occupational disease, pneumoconiosis that is often widespread on to a very kind of quartz, carbon and metal dust exposed work place.The data for the prevalence of pneumoconiosis and respiratory findings among dental laboratory technician is insufficient. The aim of this study is to determine the prevalence of pneumoconiosis and respiratory findings among dental laboratory technicians, working in province of Sivas. For this reason all the dental technicians (except 2, totally 36) participated in the study. A questionnaire which contains demographic characteristics, work conditions and symptoms were applied to all participants. Also spirometric measurements and chest x-rays were performed. The x-rays of dental technicians were evaluated by a radiologist and a chest disease specialist according to the ILO-2000 classification of pneumoconiosis. Almost half of the all participants have dyspnea and phlegm expectoration. The prevalence of pneumoconiosis was 5 (13.8%) among 36 dental technicians. There were no statistically significant differences between two groups with regard to respiratory symptoms. Values of lung function parameters of the dental technician group were not significantly different from those of control group except FEV(1). In conclusion, dental laboratory technicians are at significant risks for occupational respiratory diseases so the primary prevention rules are essential for these work places.
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Técnicos Dentales , Exposición Profesional/efectos adversos , Neumoconiosis/epidemiología , Trastornos Respiratorios/epidemiología , Adulto , Estudios de Casos y Controles , Femenino , Volumen Espiratorio Forzado , Humanos , Pulmón/diagnóstico por imagen , Pulmón/fisiopatología , Masculino , Salud Laboral , Neumoconiosis/diagnóstico por imagen , Neumoconiosis/etiología , Prevalencia , Radiografía Torácica , Trastornos Respiratorios/inducido químicamente , Trastornos Respiratorios/diagnóstico por imagen , Pruebas de Función Respiratoria , Factores de Riesgo , Espirometría , Turquía/epidemiología , Capacidad VitalAsunto(s)
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos , Anticuerpos Anticitoplasma de Neutrófilos , Humanos , Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/diagnóstico por imagen , Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/tratamiento farmacológico , Tomografía Computarizada por Rayos XRESUMEN
PURPOSE: The aim of this study was to evaluate the effects of local and systemic simvastatin application on distraction osteogenesis. MATERIALS AND METHODS: Eighteen New Zealand white rabbits underwent unilateral mandibular distraction osteogenesis. After 7 days of neutral fixation, 0.4 mm twice per day, distraction was performed for 10 days. Simvastatin was applied locally during the osteotomy phase with a gelatin sponge carrier and systemically during the distraction osteogenesis period by oral gavage. All animals were killed at the end of the consolidation period of 14 days. The distracted mandibles were harvested and evaluated by plain radiography, by peripheral quantitative computed tomography, and with histomorphometry. RESULTS: Radiographic evaluation with peripheral quantitative computed tomography showed that the area of the regenerate increased by 9.6% in the local simvastatin group and by 19.3% in the systemic simvastatin group as compared with the control group. In both experimental groups the density of the regenerate increased by 6.7% as compared with the control group. Statistical evaluation of radiographic data showed that all of these changes were not significant. Histomorphometric evaluation determined that there was no statistical difference among groups with regard to the ratios of bone tissue volume to fibrous tissue volume and bone tissue volume to marrow tissue volume. CONCLUSIONS: The results of this study suggest that simvastatin's effect on enhancing distraction regenerate is limited with the applied doses and methods.
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Regeneración Ósea/efectos de los fármacos , Inhibidores de Hidroximetilglutaril-CoA Reductasas/administración & dosificación , Mandíbula/cirugía , Osteogénesis por Distracción , Simvastatina/administración & dosificación , Administración Oral , Administración Tópica , Animales , Densidad Ósea/efectos de los fármacos , Relación Dosis-Respuesta a Droga , Avance Mandibular/métodos , ConejosRESUMEN
INTRODUCTION: Pneumoconiosis in dental technicians' has rarely been evaluated. OBJECTIVES: To evaluate clinical, functional and radiological impacts of exposure to dust on respiratory functions via chest X-ray (CXR), high-resolution computed tomography (HRCT) and spirometry in dental technicians. METHODS: Demographic data, respiratory symptoms, spirometry results, CXR and HRCT scans of 32 dental technicians were evaluated. The opacities on the radiological images were categorized based on their intensity. We investigated the relation of radiological scores with clinical, radiological and functional findings. RESULTS: The mean age of the study population was 31 ± 9 years and mean employment duration was 14 ± 9 years. Twenty-two (69%) technicians had a history of smoking. The most common symptom was phlegm, while dyspnea prevalence was higher in those with an elevated International Labour Office (ILO) profusion score (P < 0.01). Parenchymal opacities were determined in 10 (31%) technicians by CXR and in 22 (69%) technicians by HRCT (P < 0.01). There was a positive correlation between ILO profusion score and HRCT score (r = 0.765, P < 0.01). ILO profusion score and HRCT score showed positive correlation with employment duration (r = 0.599, P = 0.01; r = 0.514, P = 0.01, respectively), while exhibiting negative correlation with FVC (r = -0.509, P < 0.05; r = -0.627, P = 0.01 respectively), FVC% (r = -0.449, P < 0.05; r = -0.457, P < 0.05, respectively) and forced expiratory volume in 1 s (r = -0.473, P < 0.05; r = -0.598, P = 0.01, respectively). CONCLUSIONS: We believe that a combined approach including spirometry, CXR and HRCT modalities should be employed in demonstrating respiratory disorders associated with exposure to inorganic dusts in dental technicians.
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Técnicos Dentales/estadística & datos numéricos , Enfermedades Profesionales/diagnóstico , Neumoconiosis/diagnóstico , Espirometría/métodos , Adulto , Estudios Transversales , Polvo , Femenino , Humanos , Exposición por Inhalación/estadística & datos numéricos , Masculino , Enfermedades Profesionales/diagnóstico por imagen , Enfermedades Profesionales/epidemiología , Exposición Profesional/estadística & datos numéricos , Neumoconiosis/diagnóstico por imagen , Neumoconiosis/epidemiología , Prevalencia , Radiografía Torácica/métodos , Pruebas de Función Respiratoria/métodos , Tomografía Computarizada por Rayos X/métodos , Turquía/epidemiologíaRESUMEN
OBJECTIVE: We aimed to evaluate the effects of extra corporeal shock-wave therapy (ESWT) on the calcaneal spur length and pain severity in overweight and obese patients with symptomatic calcaneal spur. METHODS: In eighty patients with symptomatic calcaneal spur, ESWT was administered on days 0 and 7, and visual analog scale (VAS) scores and calcaneal spur lengths (CSLs) before and 3 months later after treatment were recorded. A lateral heel radiograph was used for computer-aided linear measurements of CSL. RESULTS: Of 80 patients, 59 (73.7%) were female and 21 were male (26.3%); age was 45.9 ± 8.3 years; BMI was 31.6 ± 4.4 kg/m2; and symptom duration was 2.3 ± 2.4 years. The CSL and VAS score after treatment were significantly lower than those before treatment (CSL before vs. after: 5.7 ± 1.0 vs. 4.4 ± 0.9, p = 0.001; VAS score before vs. after: 8.3 ± 1.4 vs. 4.6 ± 2.2; p = 0.03). The CSLs before and after treatment had a significant strong correlation (r = 0.832, p = 0.001). The VAS scores before and after treatment presented a significant mild correlation (r = 0.242, p = 0.03). CONCLUSIONS: In overweight and obese patients with symptomatic calcaneal spur, ESWT reduces the CSL and pain severity during a follow-up of three-month duration.
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It is well known that ceftriaxone leads to pseudolithiasis in some patients. Clinical and experimental studies also suggest that situations causing gallbladder dysfunction, such as fasting, may have a role for the development of pseudolithiasis. In this study, we prospectively evaluated the incidence and clinical importance of pseudolithiasis in paediatric surgical patients receiving ceftriaxone treatment, who often had to fast in the post-operative period. Fifty children who were given ceftriaxone were evaluated by serial abdominal sonograms. Of those, 13 (26%) developed biliary pathology. Comparison of the patients with or without pseudolithiasis revealed no significant difference with respect to age, sex, duration of the treatment and starvation variables. After cessation of the treatment, pseudolithiasis resolved spontaneously within a short period. The incidence of pseudolithiasis is not affected by fasting.
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Ceftriaxona/efectos adversos , Colelitiasis/inducido químicamente , Complicaciones Posoperatorias , Adolescente , Factores de Edad , Ceftriaxona/uso terapéutico , Niño , Preescolar , Colelitiasis/diagnóstico por imagen , Colelitiasis/epidemiología , Ayuno , Femenino , Humanos , Incidencia , Masculino , Remisión Espontánea , Factores Sexuales , Factores de Tiempo , UltrasonografíaRESUMEN
This report describes a pediatric case of delayed glossopharyngeal nerve, vagus nerve, and facial nerve palsies after a head injury. Computed tomography scan of the skull base revealed the fracture of the petrous part of the temporal bone, and the fracture involved the tip of petrous pyramid, in front of the jugular foramen. The anatomical features, mechanisms, diagnosis, and treatment are discussed.
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Enfermedades de los Nervios Craneales/etiología , Hueso Petroso/lesiones , Fractura Craneal Basilar/complicaciones , Niño , Enfermedades de los Nervios Craneales/diagnóstico , Enfermedades de los Nervios Craneales/terapia , Trastornos de Deglución/etiología , Parálisis Facial/etiología , Traumatismos Cerrados de la Cabeza/complicaciones , Traumatismos Cerrados de la Cabeza/diagnóstico por imagen , Traumatismos Cerrados de la Cabeza/terapia , Pérdida Auditiva/etiología , Humanos , Masculino , Hueso Petroso/diagnóstico por imagen , Radiografía , Fractura Craneal Basilar/diagnóstico por imagen , Fractura Craneal Basilar/terapia , Resultado del Tratamiento , Trastornos de la Voz/etiologíaRESUMEN
The aim of the present study was to examine the total orbital volume (TOV) and total orbital fat volume (TOFV) in normal orbits in different age groups and to investigate the correlation of these measurements with age, gender and body parameters by magnetic resonance imaging (MRI). MRI data were acquired retrospectively from a total of 1,453 subjects divided into five age groups with 10-year intervals. The TOV and TOFV were measured using T1-weighted MRI for each subject and body parameters were also obtained. The measurements demonstrated that TOV increased with age and that the volume was larger in men than in women. While weight and height exhibited positive correlations with TOV in male and female subjects in the 20-29, 30-39 and 40-49-year-old age groups, only weight showed a positive correlation with TOV in female subjects in the 50-59 and 60-69-year-old age groups. However, TOFV increased by age in all groups and the increments were larger in women than in men. These results provide basic information about the effect of age, gender and body parameters on TOV and TOFV. The variations in TOV are associated with orbital soft-tissues changes rather than with TOFV.
RESUMEN
PURPOSE: The aim of this study was to determine the pulmonary artery computed tomography obstruction index ratio (PACTOIR) in patients who have been diagnosed with acute pulmonary embolism (APE) with multi-slice computed tomography (MSCT) and to research the predetermination efficiency of right ventricular dysfunction (RVD) compared with echocardiography (ECHO). MATERIALS AND METHODS: One hundred patients (50 males, 50 females), who had ECHO findings and were diagnosed with APE, were subsequently examined in this study. Patients who had RVD on ECHO, tricuspid regurgitation, and pulmonary hypertension parameters that were completely positive were accepted to have RVD. RESULTS: RVD was identified in 52 patients (52 %) on echocardiography. The PACTOIR value for patients with RVD were evaluated to be significantly higher than those without RVD (41 ± 17 vs 20 ± 12 %, p < 0.001). In the ROC analysis, the PACTOIR cut-off value was 37.5 %, the sensitivity value was 67.3 %, and specificity value was 93.7 % (AUC 0.839, 95 % CI 0.752-0.905). We determined that the patients with RVD and PACTOIR values over 37.5 % can be recognized with a 92.1 % positive predictive value. CONCLUSION: Our conclusions indicated that the PACTOIR rate in RVD diagnosis in patients with APE can recognize the patients with and without RVD.
Asunto(s)
Arteria Pulmonar/diagnóstico por imagen , Embolia Pulmonar/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Disfunción Ventricular Derecha/diagnóstico por imagen , Enfermedad Aguda , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Curva ROC , Sensibilidad y Especificidad , Ultrasonografía , Disfunción Ventricular Derecha/complicacionesRESUMEN
OBJECTIVES: The aim of this 7-year follow-up study was to determine respiratory changes in dental technicians. MATERIAL AND METHODS: In our region, in the year 2005, 36 dental technicians were evaluated with a cross-sectional study on respiratory occupational diseases, and in 2012 we evaluated them again. Inclusion of information on respiratory symptoms and demographic features questionnaires was applied. Pulmonary function tests (PFT) were performed. Chest X-rays (CXR) were evaluated according to the ILO-2000 classification. For the comparisons of the technicians' findings in 2005 and 2012, data analyses were performed with the Wilcoxon test in addition to descriptive statistical procedures. RESULTS: In 2012, 19 out of the 36 technicians continued to work in the same place, so we were able to evaluate their findings. The prevalence of respiratory symptoms in dental technician was as follows: dyspnea 7 (37%), cough 6 (32%), and phlegm 5 (26%). According to ILO classifications in 2005, among the 36 technicians, 5 (13.8%) had pneumoconiosis. At the end of 7 years, there were 9 pneumoconiosis cases among the 19 remaining technicians (47%). Thus, there was a statistically significant progression on the profusion of the radiologic findings (p < 0.005). Also there was a significant worsening on spirometric findings (p < 0.05). CONCLUSION: In dental technicians, a determination of both radiologic and functional progressions at the end of 7 years demonstrate that the primary and secondary preventive measures are necessary for these workplaces. Workplaces must be regularly controlled for worker health and hygiene.