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1.

Dynein light chain 1 induces assembly of large Bim complexes on mitochondria that stabilize Mcl-1 and regulate apoptosis.

Singh, Prafull Kumar; Roukounakis, Aristomenis; Frank, Daniel O; Kirschnek, Susanne; Das, Kushal Kumar; Neumann, Simon; Madl, Josef; Römer, Winfried; Zorzin, Carina; Borner, Christoph; Haimovici, Aladin; Garcia-Saez, Ana; Weber, Arnim; Häcker, Georg.

Genes Dev; 31(17): 1754-1769, 2017 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-28982759

2.

The Coxiella burnetii T4SS effector protein AnkG hijacks the 7SK small nuclear ribonucleoprotein complex for reprogramming host cell transcription.

Cordsmeier, Arne; Rinkel, Sven; Jeninga, Myriam; Schulze-Luehrmann, Jan; Ölke, Martha; Schmid, Benedikt; Hasler, Daniele; Meister, Gunter; Häcker, Georg; Petter, Michaela; Beare, Paul A; Lührmann, Anja.

PLoS Pathog; 18(2): e1010266, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-35134097

3.

GM-CSF suppresses antioxidant signaling and drives IL-1ß secretion through NRF2 downregulation.

Di Carlo, Sara; Häcker, Georg; Gentle, Ian E.

EMBO Rep; 23(8): e54226, 2022 08 03.

Artículo en Inglés | MEDLINE | ID: mdl-35695080

4.

Epidemiological trends and susceptibility patterns of bloodstream infections caused by Enterococcus spp. in six German university hospitals: a prospectively evaluated multicentre cohort study from 2016 to 2020 of the R-Net study group.

Hornuss, Daniel; Göpel, Siri; Walker, Sarah V; Tobys, David; Häcker, Georg; Seifert, Harald; Higgins, Paul G; Xanthopoulou, Kyriaki; Gladstone, Beryl Primrose; Cattaneo, Chiara; Mischnik, Alexander; Rohde, Anna M; Imirzalioglu, Can; Trauth, Janina; Fritzenwanker, Moritz; Falgenhauer, Jane; Gastmeier, Petra; Behnke, Michael; Kramme, Evelyn; Käding, Nadja; Rupp, Jan; Peter, Silke; Schmauder, Kristina; Eisenbeis, Simone; Kern, Winfried V; Tacconelli, Evelina; Rieg, Siegbert.

Infection; 2024 Apr 30.

Artículo en Inglés | MEDLINE | ID: mdl-38684586

5.

A non-death function of the mitochondrial apoptosis apparatus in immunity.

Brokatzky, Dominik; Dörflinger, Benedikt; Haimovici, Aladin; Weber, Arnim; Kirschnek, Susanne; Vier, Juliane; Metz, Arlena; Henschel, Julia; Steinfeldt, Tobias; Gentle, Ian E; Häcker, Georg.

EMBO J; 38(11)2019 06 03.

Artículo en Inglés | MEDLINE | ID: mdl-30979778

6.

Association of ward-level antibiotic consumption with healthcare-associated Clostridioides difficile infections: an ecological study in five German university hospitals, 2017-2019.

Rohde, Anna M; Mischnik, Alexander; Behnke, Michael; Dinkelacker, Ariane; Eisenbeis, Simone; Falgenhauer, Jane; Gastmeier, Petra; Häcker, Georg; Herold, Susanne; Imirzalioglu, Can; Käding, Nadja; Kramme, Evelyn; Peter, Silke; Piepenbrock, Ellen; Rupp, Jan; Schneider, Christian; Schwab, Frank; Seifert, Harald; Steib-Bauert, Michaela; Tacconelli, Evelina; Trauth, Janina; Vehreschild, Maria J G T; Walker, Sarah V; Kern, Winfried V; Jazmati, Nathalie.

J Antimicrob Chemother; 78(9): 2274-2282, 2023 09 05.

Artículo en Inglés | MEDLINE | ID: mdl-37527398

7.

Pattern Recognition Receptors of Nucleic Acids Can Cause Sublethal Activation of the Mitochondrial Apoptosis Pathway during Viral Infection.

Gradzka-Boberda, Sylwia; Gentle, Ian E; Häcker, Georg.

J Virol; 96(18): e0121222, 2022 09 28.

Artículo en Inglés | MEDLINE | ID: mdl-36069553

8.

An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective.

Salzberger, Bernd; Mellmann, Alexander; Bludau, Anna; Ciesek, Sandra; Corman, Victor; Dilthey, Alexander; Donker, Tjibbe; Eckmanns, Tim; Egelkamp, Richard; Gatermann, Sören G; Grundmann, Hajo; Häcker, Georg; Kaase, Martin; Lange, Berit; Mielke, Martin; Pletz, Mathias W; Semmler, Torsten; Thürmer, Andrea; Wieler, Lothar H; Wolff, Thorsten; Widmer, Andreas F; Scheithauer, Simone.

Infection; 51(4): 805-811, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-37129842

9.

[Establishment of genomic pathogen surveillance to strengthen pandemic preparedness and infection prevention in Germany]. / Etablierung der Genomischen Erreger-Surveillance zur Stärkung des Pandemie- und Infektionsschutzes in Deutschland.

Scheithauer, Simone; Dilthey, Alexander; Bludau, Anna; Ciesek, Sandra; Corman, Victor; Donker, Tjibbe; Eckmanns, Tim; Egelkamp, Richard; Grundmann, Hajo; Häcker, Georg; Kaase, Martin; Lange, Berit; Mellmann, Alexander; Mielke, Martin; Pletz, Mathias; Salzberger, Bernd; Thürmer, Andrea; Widmer, Andreas; Wieler, Lothar H; Wolff, Thorsten; Gatermann, Sören; Semmler, Torsten.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz; 66(4): 443-449, 2023 Apr.

Artículo en Alemán | MEDLINE | ID: mdl-36811648

10.

The deubiquitinase Usp27x as a novel regulator of cFLIP_L protein expression and sensitizer to death-receptor-induced apoptosis.

Dold, Manuel Nico; Ng, Xiulin; Alber, Claudia; Gentle, Ian Edward; Häcker, Georg; Weber, Arnim.

Apoptosis; 27(1-2): 112-132, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-35044632

11.

Mitochondria: intracellular sentinels of infections.

Brokatzky, Dominik; Häcker, Georg.

Med Microbiol Immunol; 211(4): 161-172, 2022 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-35790577

12.

Immunization against poly-N-acetylglucosamine reduces neutrophil activation and GVHD while sparing microbial diversity.

Hülsdünker, Jan; Thomas, Oliver S; Haring, Eileen; Unger, Susanne; Gonzalo Núñez, Nicolás; Tugues, Sonia; Gao, Zhan; Duquesne, Sandra; Cywes-Bentley, Colette; Oyardi, Ozlem; Kirschnek, Susanne; Schmitt-Graeff, Annette; Pabst, Oliver; Koenecke, Christian; Duyster, Justus; Apostolova, Petya; Blaser, Martin J; Becher, Burkhard; Pier, Gerald B; Häcker, Georg; Zeiser, Robert.

Proc Natl Acad Sci U S A; 116(41): 20700-20706, 2019 10 08.

Artículo en Inglés | MEDLINE | ID: mdl-31527267

13.

The Reaction of Innate Lymphoid Cells in the Mouse Female Genital Tract to Chlamydial Infection.

Barth, Svenja; Kirschnek, Susanne; Ortmann, Noemi; Tanriver, Yakup; Häcker, Georg.

Infect Immun; 89(11): e0080020, 2021 10 15.

Artículo en Inglés | MEDLINE | ID: mdl-34424753

14.

Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

Vince, James E; Wong, W Wei-Lynn; Gentle, Ian; Lawlor, Kate E; Allam, Ramanjaneyulu; O'Reilly, Lorraine; Mason, Kylie; Gross, Olaf; Ma, Stephen; Guarda, Greta; Anderton, Holly; Castillo, Rosa; Häcker, Georg; Silke, John; Tschopp, Jürg.

Immunity; 36(2): 215-27, 2012 Feb 24.

Artículo en Inglés | MEDLINE | ID: mdl-22365665

15.

Checkpoint kinase 1 is essential for fetal and adult hematopoiesis.

Schuler, Fabian; Afreen, Sehar; Manzl, Claudia; Häcker, Georg; Erlacher, Miriam; Villunger, Andreas.

EMBO Rep; 20(8): e47026, 2019 08.

Artículo en Inglés | MEDLINE | ID: mdl-31379128

16.

Apoptosis Functions in Defense against Infection of Mammalian Cells with Environmental Chlamydiae.

Brokatzky, Dominik; Kretz, Oliver; Häcker, Georg.

Infect Immun; 88(6)2020 05 20.

Artículo en Inglés | MEDLINE | ID: mdl-32179584

17.

Vancomycin-resistant Enterococcus faecium colonizing patients on hospital admission in Germany: prevalence and molecular epidemiology.

Xanthopoulou, Kyriaki; Peter, Silke; Tobys, David; Behnke, Michael; Dinkelacker, Ariane G; Eisenbeis, Simone; Falgenhauer, Jane; Falgenhauer, Linda; Fritzenwanker, Moritz; Gölz, Hannah; Häcker, Georg; Higgins, Paul G; Imirzalioglu, Can; Käding, Nadja; Kern, Winfried V; Kramme, Evelyn; Kola, Axel; Mischnik, Alexander; Rieg, Siegbert; Rohde, Anna M; Rupp, Jan; Tacconelli, Evelina; Vehreschild, Maria J G T; Walker, Sarah V; Gastmeier, Petra; Seifert, Harald.

J Antimicrob Chemother; 75(10): 2743-2751, 2020 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-32699884

18.

Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset.

Hülsdünker, Jan; Ottmüller, Katja J; Neeff, Hannes P; Koyama, Motoko; Gao, Zhan; Thomas, Oliver S; Follo, Marie; Al-Ahmad, Ali; Prinz, Gabriele; Duquesne, Sandra; Dierbach, Heide; Kirschnek, Susanne; Lämmermann, Tim; Blaser, Martin J; Fife, Brian T; Blazar, Bruce R; Beilhack, Andreas; Hill, Geoffrey R; Häcker, Georg; Zeiser, Robert.

Blood; 131(16): 1858-1869, 2018 04 19.

Artículo en Inglés | MEDLINE | ID: mdl-29463561

19.

Infection of HeLa cells with Chlamydia trachomatis inhibits protein synthesis and causes multiple changes to host cell pathways.

Ohmer, Michaela; Tzivelekidis, Tina; Niedenführ, Nora; Volceanov-Hahn, Larisa; Barth, Svenja; Vier, Juliane; Börries, Melanie; Busch, Hauke; Kook, Lucas; Biniossek, Martin L; Schilling, Oliver; Kirschnek, Susanne; Häcker, Georg.

Cell Microbiol; 21(4): e12993, 2019 04.

Artículo en Inglés | MEDLINE | ID: mdl-30551267

20.

GVHD prediction based on the microbiome.

Häcker, Georg.

Blood; 140(22): 2313-2314, 2022 12 01.

Artículo en Inglés | MEDLINE | ID: mdl-36454594

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