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1.

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

Li, Hanjie; van der Leun, Anne M; Yofe, Ido; Lubling, Yaniv; Gelbard-Solodkin, Dikla; van Akkooi, Alexander C J; van den Braber, Marlous; Rozeman, Elisa A; Haanen, John B A G; Blank, Christian U; Horlings, Hugo M; David, Eyal; Baran, Yael; Bercovich, Akhiad; Lifshitz, Aviezer; Schumacher, Ton N; Tanay, Amos; Amit, Ido.

Cell; 176(4): 775-789.e18, 2019 02 07.

Artículo en Inglés | MEDLINE | ID: mdl-30595452

2.

Converting Cold into Hot Tumors by Combining Immunotherapies.

Haanen, John B A G.

Cell; 170(6): 1055-1056, 2017 09 07.

Artículo en Inglés | MEDLINE | ID: mdl-28886376

3.

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

Li, Hanjie; van der Leun, Anne M; Yofe, Ido; Lubling, Yaniv; Gelbard-Solodkin, Dikla; van Akkooi, Alexander C J; van den Braber, Marlous; Rozeman, Elisa A; Haanen, John B A G; Blank, Christian U; Horlings, Hugo M; David, Eyal; Baran, Yael; Bercovich, Akhiad; Lifshitz, Aviezer; Schumacher, Ton N; Tanay, Amos; Amit, Ido.

Cell; 181(3): 747, 2020 Apr 30.

Artículo en Inglés | MEDLINE | ID: mdl-32359441

4.

Severe Immune-Related Enteritis after In Utero Exposure to Pembrolizumab.

Baarslag, Manuel A; Heimovaara, Joosje H; Borgers, Jessica S W; van Aerde, Koen J; Koenen, Hans J P M; Smeets, Ruben L; Buitelaar, Pauline L M; Pluim, Dick; Vos, Shoko; Henriet, Stefanie S V; de Groot, Jan Willem B; van Grotel, Martine; Rosing, Hilde; Beijnen, Jos H; Huitema, Alwin D R; Haanen, John B A G; Amant, Frédéric; Gierenz, Nicole.

N Engl J Med; 389(19): 1790-1796, 2023 Nov 09.

Artículo en Inglés | MEDLINE | ID: mdl-37937778

5.

A prediction model for response to immune checkpoint inhibition in advanced melanoma.

van Duin, Isabella A J; Verheijden, Rik J; van Diest, Paul J; Blokx, Willeke A M; El-Sharouni, Mary-Ann; Verhoeff, Joost J C; Leiner, Tim; van den Eertwegh, Alfonsus J M; de Groot, Jan Willem B; van Not, Olivier J; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blank, Christian U; Haanen, John B A G; Hospers, Geke A P; Piersma, Djura; van Rijn, Rozemarijn S; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Wouters, Michel W J M; Stevense-den Boer, Marion A M; Boers-Sonderen, Marye J; Kapiteijn, Ellen; Suijkerbuijk, Karijn P M; Elias, Sjoerd G.

Int J Cancer; 154(10): 1760-1771, 2024 May 15.

Artículo en Inglés | MEDLINE | ID: mdl-38296842

6.

Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response.

Gangaev, Anastasia; Rozeman, Elisa A; Rohaan, Maartje W; Isaeva, Olga I; Philips, Daisy; Patiwael, Sanne; van den Berg, Joost H; Ribas, Antoni; Schadendorf, Dirk; Schilling, Bastian; Schumacher, Ton N; Blank, Christian U; Haanen, John B A G; Kvistborg, Pia.

Proc Natl Acad Sci U S A; 118(43)2021 10 26.

Artículo en Inglés | MEDLINE | ID: mdl-34670835

7.

Time interval from primary melanoma to first distant recurrence in relation to patient outcomes in advanced melanoma.

van Duin, Isabella A J; Elias, Sjoerd G; van den Eertwegh, Alfonsus J M; de Groot, Jan Willem B; Blokx, Willeke A M; van Diest, Paul J; Leiner, Tim; Verhoeff, Joost J C; Verheijden, Rik J; van Not, Olivier J; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blank, Christian U; Haanen, John B A G; Hospers, Geke A P; Kamphuis, Anna M; Piersma, Djura; van Rijn, Rozemarijn S; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Wouters, Michel W J M; Stevense-den Boer, Marion A M; Boers-Sonderen, Marye J; Kapiteijn, Ellen; Suijkerbuijk, Karijn P M.

Int J Cancer; 152(12): 2493-2502, 2023 06 15.

Artículo en Inglés | MEDLINE | ID: mdl-36843274

8.

Novel strategies to improve efficacy of treatment with tumor-infiltrating lymphocytes (TILs) for patients with solid cancers.

Tas, Liselotte; Jedema, Inge; Haanen, John B A G.

Curr Opin Oncol; 35(2): 107-113, 2023 03 01.

Artículo en Inglés | MEDLINE | ID: mdl-36607824

9.

Oncological Outcome After Lymph Node Dissection for Cutaneous Squamous Cell Carcinoma.

Huis In 't Veld, Eva A; Boere, Thomas; Zuur, Charlotte L; Wouters, Michel W; van Akkooi, Alexander C J; Haanen, John B A G; Crijns, Marianne B; Smith, Myles J; Mooyaart, Antien; Wakkee, Marlies; Sewnaik, Aniel; Strauss, Dirk C; Grunhagen, Dirk J; Verhoef, Cornelis; Hayes, Andrew J; van Houdt, Winan J.

Ann Surg Oncol; 30(8): 5017-5026, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-36991168

10.

Is a History of Optimal Staging by Sentinel Lymph Node Biopsy in the Era Prior to Adjuvant Therapy Associated with Improved Outcome Once Melanoma Patients have Progressed to Advanced Disease?

Blankenstein, Stephanie A; Bonenkamp, Johannes J; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blank, Christian U; Blokx, Willeke A M; Boers-Sonderen, Marye J; van den Eertwegh, Alfons J M; Franken, Margreet G; de Groot, Jan Willem B; Haanen, John B A G; Hospers, Geke A P; Kapiteijn, Ellen W; van Not, Olivier J; Piersma, Djura; van Rijn, Rozemarijn S; Suijkerbuijk, Karijn P M; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Westgeest, Hans M; Wouters, Michel W J M; van Akkooi, Alexander C J.

Ann Surg Oncol; 30(1): 573-586, 2023 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-36203067

11.

Discontinuation of anti-PD-1 monotherapy in advanced melanoma-Outcomes of daily clinical practice.

van Zeijl, Michiel C T; van den Eertwegh, Alfons J M; Wouters, Michel W J M; de Wreede, Liesbeth C; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; de Groot, Jan-Willem B; Hospers, Geke A P; Kapiteijn, Ellen; Piersma, Djura; van Rijn, Rozemarijn S; Suijkerbuijk, Karijn P M; Ten Tije, Albert J; van der Veldt, Astrid A M; Vreugdenhil, Gerard; van der Hoeven, Jacobus J M; Haanen, John B A G.

Int J Cancer; 150(2): 317-326, 2022 01 15.

Artículo en Inglés | MEDLINE | ID: mdl-34520567

12.

Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma.

Robert, Caroline; Grob, Jean J; Stroyakovskiy, Daniil; Karaszewska, Boguslawa; Hauschild, Axel; Levchenko, Evgeny; Chiarion Sileni, Vanna; Schachter, Jacob; Garbe, Claus; Bondarenko, Igor; Gogas, Helen; Mandalá, Mario; Haanen, John B A G; Lebbé, Celeste; Mackiewicz, Andrzej; Rutkowski, Piotr; Nathan, Paul D; Ribas, Antoni; Davies, Michael A; Flaherty, Keith T; Burgess, Paul; Tan, Monique; Gasal, Eduard; Voi, Maurizio; Schadendorf, Dirk; Long, Georgina V.

N Engl J Med; 381(7): 626-636, 2019 08 15.

Artículo en Inglés | MEDLINE | ID: mdl-31166680

13.

[¹⁸F]FDG-PET accurately identifies pathological response early upon neoadjuvant immune checkpoint blockade in head and neck squamous cell carcinoma.

Vos, Joris L; Zuur, Charlotte L; Smit, Laura A; de Boer, Jan Paul; Al-Mamgani, Abrahim; van den Brekel, Michiel W M; Haanen, John B A G; Vogel, Wouter V.

Eur J Nucl Med Mol Imaging; 49(6): 2010-2022, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-34957526

14.

Neoadjuvant nivolumab + T-VEC combination therapy for resectable early stage or metastatic (IIIB-IVM1a) melanoma with injectable disease: study protocol of the NIVEC trial.

Rohaan, Maartje W; Stahlie, Emma H A; Franke, Viola; Zijlker, Lisanne P; Wilgenhof, Sofie; van der Noort, Vincent; van Akkooi, Alexander C J; Haanen, John B A G.

BMC Cancer; 22(1): 851, 2022 Aug 04.

Artículo en Inglés | MEDLINE | ID: mdl-35927710

15.

Neoantigen landscape dynamics during human melanoma-T cell interactions.

Verdegaal, Els M E; de Miranda, Noel F C C; Visser, Marten; Harryvan, Tom; van Buuren, Marit M; Andersen, Rikke S; Hadrup, Sine R; van der Minne, Caroline E; Schotte, Remko; Spits, Hergen; Haanen, John B A G; Kapiteijn, Ellen H W; Schumacher, Ton N; van der Burg, Sjoerd H.

Nature; 536(7614): 91-5, 2016 08 04.

Artículo en Inglés | MEDLINE | ID: mdl-27350335

16.

Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease : A Cohort Study.

van der Kooij, Monique K; Suijkerbuijk, Karijn P M; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blank, Christian U; Boers-Sonderen, Marye J; van Breeschoten, Jesper; van den Eertwegh, Alfonsus J M; de Groot, Jan Willem B; Haanen, John B A G; Hospers, Geke A P; Piersma, Djura; van Rijn, Rozemarijn S; Ten Tije, Albert J; van der Veldt, Astrid A M; Vreugdenhil, Gerard; van Zeijl, Michiel C T; Wouters, Michel W J M; Dekkers, Olaf M; Kapiteijn, Ellen.

Ann Intern Med; 174(5): 641-648, 2021 05.

Artículo en Inglés | MEDLINE | ID: mdl-33587686

17.

Immunotherapy for cancer treatment during pregnancy.

Borgers, Jessica S W; Heimovaara, Joosje H; Cardonick, Elyce; Dierickx, Daan; Lambertini, Matteo; Haanen, John B A G; Amant, Frédéric.

Lancet Oncol; 22(12): e550-e561, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34856152

18.

mRNA-1273 COVID-19 vaccination in patients receiving chemotherapy, immunotherapy, or chemoimmunotherapy for solid tumours: a prospective, multicentre, non-inferiority trial.

Oosting, Sjoukje F; van der Veldt, Astrid A M; GeurtsvanKessel, Corine H; Fehrmann, Rudolf S N; van Binnendijk, Rob S; Dingemans, Anne-Marie C; Smit, Egbert F; Hiltermann, T Jeroen N; den Hartog, Gerco; Jalving, Mathilda; Westphal, Tatjana T; Bhattacharya, Arkajyoti; van der Heiden, Marieke; Rimmelzwaan, Guus F; Kvistborg, Pia; Blank, Christian U; Koopmans, Marion P G; Huckriede, Anke L W; van Els, Cecile A C M; Rots, Nynke Y; van Baarle, Debbie; Haanen, John B A G; de Vries, Elisabeth G E.

Lancet Oncol; 22(12): 1681-1691, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34767759

19.

Neoadjuvant Cytoreductive Treatment With BRAF/MEK Inhibition of Prior Unresectable Regionally Advanced Melanoma to Allow Complete Surgical Resection, REDUCTOR: A Prospective, Single-arm, Open-label Phase II Trial.

Blankenstein, Stéphanie A; Rohaan, Maartje W; Klop, Willem Martin C; van der Hiel, Bernies; van de Wiel, Bart A; Lahaye, Max J; Adriaansz, Sandra; Sikorska, Karolina; van Tinteren, Harm; Sari, Aysegül; Grijpink-Ongering, Lindsay G; van Houdt, Winan J; Wouters, Michel W J M; Blank, Christian U; Wilgenhof, Sofie; van Thienen, Johannes V; van Akkooi, Alexander C J; Haanen, John B A G.

Ann Surg; 274(2): 383-389, 2021 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-33843797

20.

Tumor-Infiltrating Lymphocyte Therapy in Advanced Melanoma. Reply.

Rohaan, Maartje W; Kessels, Rob; Haanen, John B A G.

N Engl J Med; 388(9): 859-860, 2023 Mar 02.

Artículo en Inglés | MEDLINE | ID: mdl-36856631

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Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

Converting Cold into Hot Tumors by Combining Immunotherapies.

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

Severe Immune-Related Enteritis after In Utero Exposure to Pembrolizumab.

A prediction model for response to immune checkpoint inhibition in advanced melanoma.

Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response.

Time interval from primary melanoma to first distant recurrence in relation to patient outcomes in advanced melanoma.

Novel strategies to improve efficacy of treatment with tumor-infiltrating lymphocytes (TILs) for patients with solid cancers.

Oncological Outcome After Lymph Node Dissection for Cutaneous Squamous Cell Carcinoma.

Is a History of Optimal Staging by Sentinel Lymph Node Biopsy in the Era Prior to Adjuvant Therapy Associated with Improved Outcome Once Melanoma Patients have Progressed to Advanced Disease?

Discontinuation of anti-PD-1 monotherapy in advanced melanoma-Outcomes of daily clinical practice.

Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma.

[¹⁸F]FDG-PET accurately identifies pathological response early upon neoadjuvant immune checkpoint blockade in head and neck squamous cell carcinoma.

Neoadjuvant nivolumab + T-VEC combination therapy for resectable early stage or metastatic (IIIB-IVM1a) melanoma with injectable disease: study protocol of the NIVEC trial.

Neoantigen landscape dynamics during human melanoma-T cell interactions.

Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease : A Cohort Study.

Immunotherapy for cancer treatment during pregnancy.

mRNA-1273 COVID-19 vaccination in patients receiving chemotherapy, immunotherapy, or chemoimmunotherapy for solid tumours: a prospective, multicentre, non-inferiority trial.

Neoadjuvant Cytoreductive Treatment With BRAF/MEK Inhibition of Prior Unresectable Regionally Advanced Melanoma to Allow Complete Surgical Resection, REDUCTOR: A Prospective, Single-arm, Open-label Phase II Trial.

Tumor-Infiltrating Lymphocyte Therapy in Advanced Melanoma. Reply.