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1.

Sarah A. Hills RGN MSc, 28 September 1960-1 May 2023.

Boulton, Andrew J M; Ferrannini, Ele; Halban, Philippe A.

Diabetologia; 66(8): 1355-1356, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-37328553

2.

Short term exposure of beta cells to low concentrations of interleukin-1ß improves insulin secretion through focal adhesion and actin remodeling and regulation of gene expression.

Arous, Caroline; Ferreira, Pedro G; Dermitzakis, Emmanouil T; Halban, Philippe A.

J Biol Chem; 290(10): 6653-69, 2015 Mar 06.

Artículo en Inglés | MEDLINE | ID: mdl-25586177

3.

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome.

Nica, Alexandra C; Ongen, Halit; Irminger, Jean-Claude; Bosco, Domenico; Berney, Thierry; Antonarakis, Stylianos E; Halban, Philippe A; Dermitzakis, Emmanouil T.

Genome Res; 23(9): 1554-62, 2013 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-23716500

4.

50 years forward: beta cells.

Halban, Philippe A.

Diabetologia; 58(8): 1688-92, 2015 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-25957776

5.

The skeleton in the closet: actin cytoskeletal remodeling in ß-cell function.

Arous, Caroline; Halban, Philippe A.

Am J Physiol Endocrinol Metab; 309(7): E611-20, 2015 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-26286869

6.

Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretion.

Rondas, Dieter; Tomas, Alejandra; Soto-Ribeiro, Martinho; Wehrle-Haller, Bernhard; Halban, Philippe A.

J Biol Chem; 287(4): 2423-36, 2012 Jan 20.

Artículo en Inglés | MEDLINE | ID: mdl-22139838

7.

Regulation of insulin secretion by phosphatidylinositol-4,5-bisphosphate.

Tomas, Alejandra; Yermen, Barbara; Regazzi, Romano; Pessin, Jeffrey E; Halban, Philippe A.

Traffic; 11(1): 123-37, 2010 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-19845918

8.

Short term exposure of beta cells to low concentrations of interleukin-1ß improves insulin secretion through focal adhesion and actin remodeling and regulation of gene expression.

Arous, Caroline; Ferreira, Pedro G; Dermitzakis, Emmanouil T; Halban, Philippe A.

J Biol Chem; 290(23): 14491, 2015 Jun 05.

Artículo en Inglés | MEDLINE | ID: mdl-26048996

9.

Cellular sources of new pancreatic beta cells and therapeutic implications for regenerative medicine.

Halban, Philippe A.

Nat Cell Biol; 6(11): 1021-5, 2004 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-15516994

10.

Interleukin-6 regulates pancreatic alpha-cell mass expansion.

Ellingsgaard, Helga; Ehses, Jan A; Hammar, Eva B; Van Lommel, Leentje; Quintens, Roel; Martens, Geert; Kerr-Conte, Julie; Pattou, Francois; Berney, Thierry; Pipeleers, Daniel; Halban, Philippe A; Schuit, Frans C; Donath, Marc Y.

Proc Natl Acad Sci U S A; 105(35): 13163-8, 2008 Sep 02.

Artículo en Inglés | MEDLINE | ID: mdl-18719127

11.

Munc 18-1 and granuphilin collaborate during insulin granule exocytosis.

Tomas, Alejandra; Meda, Paolo; Regazzi, Romano; Pessin, Jeffrey E; Halban, Philippe A.

Traffic; 9(5): 813-32, 2008 May.

Artículo en Inglés | MEDLINE | ID: mdl-18208509

12.

Silencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta cells from tumor necrosis factor-alpha-induced decrease of IRS-2 and inhibition of glucose-stimulated insulin secretion.

Bouzakri, Karim; Ribaux, Pascale; Halban, Philippe A.

J Biol Chem; 284(41): 27892-27898, 2009 Oct 09.

Artículo en Inglés | MEDLINE | ID: mdl-19690174

13.

Dual effect of cell-cell contact disruption on cytosolic calcium and insulin secretion.

Jaques, Fabienne; Jousset, Hélène; Tomas, Alejandra; Prost, Anne-Lise; Wollheim, Claes B; Irminger, Jean-Claude; Demaurex, Nicolas; Halban, Philippe A.

Endocrinology; 149(5): 2494-505, 2008 May.

Artículo en Inglés | MEDLINE | ID: mdl-18218692

14.

Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.

Böni-Schnetzler, Marianne; Thorne, Jeffrey; Parnaud, Géraldine; Marselli, Lorella; Ehses, Jan A; Kerr-Conte, Julie; Pattou, Francois; Halban, Philippe A; Weir, Gordon C; Donath, Marc Y.

J Clin Endocrinol Metab; 93(10): 4065-74, 2008 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-18664535

15.

Pro-survival role of gelsolin in mouse beta-cells.

Yermen, Barbara; Tomas, Alejandra; Halban, Philippe A.

Diabetes; 56(1): 80-7, 2007 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-17192468

16.

Diabetes research investment in the European Union.

Halban, Philippe A; Ferrannini, Ele; Nerup, Jørn.

Nat Med; 12(1): 70-2, 2006 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-16397573

17.

Induction of CXCL1 by extracellular matrix and autocrine enhancement by interleukin-1 in rat pancreatic beta-cells.

Ribaux, Pascale; Ehses, Jan A; Lin-Marq, Nathalie; Carrozzino, Fabio; Böni-Schnetzler, Marianne; Hammar, Eva; Irminger, Jean-Claude; Donath, Marc Y; Halban, Philippe A.

Endocrinology; 148(11): 5582-90, 2007 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-17702850

18.

Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death.

Marzban, Lucy; Rhodes, Christopher J; Steiner, Donald F; Haataja, Leena; Halban, Philippe A; Verchere, C Bruce.

Diabetes; 55(8): 2192-201, 2006 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-16873681

19.

Blockade of beta1 integrin-laminin-5 interaction affects spreading and insulin secretion of rat beta-cells attached on extracellular matrix.

Parnaud, Geraldine; Hammar, Eva; Rouiller, Dominique G; Armanet, Mathieu; Halban, Philippe A; Bosco, Domenico.

Diabetes; 55(5): 1413-20, 2006 May.

Artículo en Inglés | MEDLINE | ID: mdl-16644699

20.

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets.

Maedler, Kathrin; Sergeev, Pavel; Ris, Frédéric; Oberholzer, José; Joller-Jemelka, Helen I; Spinas, Giatgen A; Kaiser, Nurit; Halban, Philippe A; Donath, Marc Y.

J Clin Invest; 110(6): 851-60, 2002 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-12235117

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Sarah A. Hills RGN MSc, 28 September 1960-1 May 2023.

Short term exposure of beta cells to low concentrations of interleukin-1ß improves insulin secretion through focal adhesion and actin remodeling and regulation of gene expression.

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome.

50 years forward: beta cells.

The skeleton in the closet: actin cytoskeletal remodeling in ß-cell function.

Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretion.

Regulation of insulin secretion by phosphatidylinositol-4,5-bisphosphate.

Short term exposure of beta cells to low concentrations of interleukin-1ß improves insulin secretion through focal adhesion and actin remodeling and regulation of gene expression.

Cellular sources of new pancreatic beta cells and therapeutic implications for regenerative medicine.

Interleukin-6 regulates pancreatic alpha-cell mass expansion.

Munc 18-1 and granuphilin collaborate during insulin granule exocytosis.

Silencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta cells from tumor necrosis factor-alpha-induced decrease of IRS-2 and inhibition of glucose-stimulated insulin secretion.

Dual effect of cell-cell contact disruption on cytosolic calcium and insulin secretion.

Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.

Pro-survival role of gelsolin in mouse beta-cells.

Diabetes research investment in the European Union.

Induction of CXCL1 by extracellular matrix and autocrine enhancement by interleukin-1 in rat pancreatic beta-cells.

Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death.

Blockade of beta1 integrin-laminin-5 interaction affects spreading and insulin secretion of rat beta-cells attached on extracellular matrix.

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets.