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1.
Acid ceramidase involved in pathogenic cascade leading to accumulation of α-synuclein in iPSC model of GBA1-associated Parkinson's disease.
Hum Mol Genet;
32(11): 1888-1900, 2023 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36752535
2.
Cell type-specific lipid storage changes in Parkinson's disease patient brains are recapitulated by experimental glycolipid disturbance.
Proc Natl Acad Sci U S A;
117(44): 27646-27654, 2020 11 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33060302
3.
Glycosphingolipid metabolism and its role in ageing and Parkinson's disease.
Glycoconj J;
39(1): 39-53, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34757540
4.
Mitochondrial clearance and maturation of autophagosomes are compromised in LRRK2 G2019S familial Parkinson's disease patient fibroblasts.
Hum Mol Genet;
28(19): 3232-3243, 2019 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31261377
5.
Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson's disease.
J Neuroinflammation;
16(1): 153, 2019 Jul 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-31331333
6.
The glycoprotein GPNMB is selectively elevated in the substantia nigra of Parkinson's disease patients and increases after lysosomal stress.
Neurobiol Dis;
120: 1-11, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30149180
7.
Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's disease.
Hum Mol Genet;
23(17): 4510-27, 2014 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24728190
8.
Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons.
Neurobiol Dis;
82: 495-503, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26392287
9.
Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease.
Neurobiol Dis;
64: 79-87, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24388974
10.
Transcript expression levels of full-length alpha-synuclein and its three alternatively spliced variants in Parkinson's disease brain regions and in a transgenic mouse model of alpha-synuclein overexpression.
Mol Cell Neurosci;
49(2): 230-9, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22155155
11.
Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats.
Proc Natl Acad Sci U S A;
107(36): 15921-6, 2010 Sep 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-20798034
12.
Loss of Lipid Carrier ApoE Exacerbates Brain Glial and Inflammatory Responses after Lysosomal GBA1 Inhibition.
Cells;
12(21)2023 11 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-37947642
13.
Viral-like TLR3 induction of cytokine networks and α-synuclein are reduced by complement C3 blockade in mouse brain.
Sci Rep;
13(1): 15164, 2023 09 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-37704739
14.
Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons.
bioRxiv;
2023 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37214873
15.
α-Synuclein overexpressing transgenic mice show internal organ pathology and autonomic deficits.
Neurobiol Dis;
47(2): 258-67, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22549133
16.
Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression.
Proc Natl Acad Sci U S A;
106(52): 22474-9, 2009 Dec 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-20007772
17.
The Toll-like receptor-3 agonist polyinosinic:polycytidylic acid triggers nigrostriatal dopaminergic degeneration.
J Neurosci;
30(48): 16091-101, 2010 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21123556
18.
Fibroblasts from idiopathic Parkinson's disease exhibit deficiency of lysosomal glucocerebrosidase activity associated with reduced levels of the trafficking receptor LIMP2.
Mol Brain;
14(1): 16, 2021 01 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-33468204
19.
PSD-95 uncouples dopamine-glutamate interaction in the D1/PSD-95/NMDA receptor complex.
J Neurosci;
29(9): 2948-60, 2009 Mar 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-19261890
20.
Experimental studies of mitochondrial and lysosomal function in in vitro and in vivo models relevant to Parkinson's disease genetic risk.
Int Rev Neurobiol;
154: 279-302, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32739007