1.
J Am Chem Soc
; 134(21): 8794-7, 2012 May 30.
Artículo
en Inglés
| MEDLINE
| ID: mdl-22583475
RESUMEN
Catalytic asymmetric chloride and bromide ring openings of meso aziridines with trimethylsilyl halides have been developed using modular chiral 1,2,3-triazolium chlorides as catalysts. Control experiments suggest the reaction pathway involving hypervalent silicate ions as reactive intermediates. The application of this system to the efficient kinetic resolution of terminal aziridines is also reported.