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1.

Interleukin-22: immunobiology and pathology.

Dudakov, Jarrod A; Hanash, Alan M; van den Brink, Marcel R M.

Annu Rev Immunol; 33: 747-85, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-25706098

2.

The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design.

Saxton, Robert A; Henneberg, Lukas T; Calafiore, Marco; Su, Leon; Jude, Kevin M; Hanash, Alan M; Garcia, K Christopher.

Immunity; 54(4): 660-672.e9, 2021 04 13.

Artículo en Inglés | MEDLINE | ID: mdl-33852830

3.

Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease.

Mathewson, Nathan D; Jenq, Robert; Mathew, Anna V; Koenigsknecht, Mark; Hanash, Alan; Toubai, Tomomi; Oravecz-Wilson, Katherine; Wu, Shin-Rong; Sun, Yaping; Rossi, Corinne; Fujiwara, Hideaki; Byun, Jaeman; Shono, Yusuke; Lindemans, Caroline; Calafiore, Marco; Schmidt, Thomas M; Honda, Kenya; Young, Vincent B; Pennathur, Subramaniam; van den Brink, Marcel; Reddy, Pavan.

Nat Immunol; 17(5): 505-513, 2016 05.

Artículo en Inglés | MEDLINE | ID: mdl-26998764

4.

T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation.

Fu, Ya-Yuan; Egorova, Anastasiya; Sobieski, Catherine; Kuttiyara, Jason; Calafiore, Marco; Takashima, Shuichiro; Clevers, Hans; Hanash, Alan M.

Immunity; 51(1): 90-103.e3, 2019 07 16.

Artículo en Inglés | MEDLINE | ID: mdl-31278057

5.

Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance.

Campbell, Clarissa; Dikiy, Stanislav; Bhattarai, Shakti K; Chinen, Takatoshi; Matheis, Fanny; Calafiore, Marco; Hoyos, Beatrice; Hanash, Alan; Mucida, Daniel; Bucci, Vanni; Rudensky, Alexander Y.

Immunity; 48(6): 1245-1257.e9, 2018 06 19.

Artículo en Inglés | MEDLINE | ID: mdl-29858010

6.

A phase 2 study of interleukin-22 and systemic corticosteroids as initial treatment for acute GVHD of the lower GI tract.

Ponce, Doris M; Alousi, Amin M; Nakamura, Ryotaro; Slingerland, John; Calafiore, Marco; Sandhu, Karamjeet S; Barker, Juliet N; Devlin, Sean; Shia, Jinru; Giralt, Sergio; Perales, Miguel-Angel; Moore, Gillian; Fatmi, Samira; Soto, Cristina; Gomes, Antonio; Giardina, Paul; Marcello, LeeAnn; Yan, Xiaoqiang; Tang, Tom; Dreyer, Kevin; Chen, Jianmin; Daley, William L; Peled, Jonathan U; van den Brink, Marcel R M; Hanash, Alan M.

Blood; 141(12): 1389-1401, 2023 03 23.

Artículo en Inglés | MEDLINE | ID: mdl-36399701

7.

Corrigendum: Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease.

Mathewson, Nathan D; Jenq, Robert; Mathew, Anna V; Koenigsknecht, Mark; Hanash, Alan; Toubai, Tomomi; Oravecz-Wilson, Katherine; Wu, Shin-Rong; Sun, Yaping; Rossi, Corinne; Fujiwara, Hideaki; Byun, Jaeman; Shono, Yusuke; Lindemans, Caroline; Calafiore, Marco; Schmidt, Thomas M; Honda, Kenya; Young, Vincent B; Pennathur, Subramaniam; van den Brink, Marcel; Reddy, Pavan.

Nat Immunol; 17(10): 1235, 2016 09 20.

Artículo en Inglés | MEDLINE | ID: mdl-27648549

8.

Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease.

Hanash, Alan M; Dudakov, Jarrod A; Hua, Guoqiang; O'Connor, Margaret H; Young, Lauren F; Singer, Natalie V; West, Mallory L; Jenq, Robert R; Holland, Amanda M; Kappel, Lucy W; Ghosh, Arnab; Tsai, Jennifer J; Rao, Uttam K; Yim, Nury L; Smith, Odette M; Velardi, Enrico; Hawryluk, Elena B; Murphy, George F; Liu, Chen; Fouser, Lynette A; Kolesnick, Richard; Blazar, Bruce R; van den Brink, Marcel R M.

Immunity; 37(2): 339-50, 2012 Aug 24.

Artículo en Inglés | MEDLINE | ID: mdl-22921121

9.

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration.

Lindemans, Caroline A; Calafiore, Marco; Mertelsmann, Anna M; O'Connor, Margaret H; Dudakov, Jarrod A; Jenq, Robert R; Velardi, Enrico; Young, Lauren F; Smith, Odette M; Lawrence, Gillian; Ivanov, Juliet A; Fu, Ya-Yuan; Takashima, Shuichiro; Hua, Guoqiang; Martin, Maria L; O'Rourke, Kevin P; Lo, Yuan-Hung; Mokry, Michal; Romera-Hernandez, Monica; Cupedo, Tom; Dow, Lukas; Nieuwenhuis, Edward E; Shroyer, Noah F; Liu, Chen; Kolesnick, Richard; van den Brink, Marcel R M; Hanash, Alan M.

Nature; 528(7583): 560-564, 2015 Dec 24.

Artículo en Inglés | MEDLINE | ID: mdl-26649819

10.

Nrf2 regulates CD4⁺ T cell-induced acute graft-versus-host disease in mice.

Tsai, Jennifer J; Velardi, Enrico; Shono, Yusuke; Argyropoulos, Kimon V; Holland, Amanda M; Smith, Odette M; Yim, Nury L; Rao, Uttam K; Kreines, Fabiana M; Lieberman, Sophie R; Young, Lauren F; Lazrak, Amina; Youssef, Salma; Fu, Ya-Yuan; Liu, Chen; Lezcano, Cecilia; Murphy, George F; Na, Il-Kang; Jenq, Robert R; Hanash, Alan M; Dudakov, Jarrod A; van den Brink, Marcel R M.

Blood; 132(26): 2763-2774, 2018 12 27.

Artículo en Inglés | MEDLINE | ID: mdl-30381375

11.

Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease.

Dudakov, Jarrod A; Mertelsmann, Anna M; O'Connor, Margaret H; Jenq, Robert R; Velardi, Enrico; Young, Lauren F; Smith, Odette M; Boyd, Richard L; van den Brink, Marcel R M; Hanash, Alan M.

Blood; 130(7): 933-942, 2017 08 17.

Artículo en Inglés | MEDLINE | ID: mdl-28607133

12.

Role of the intestinal mucosa in acute gastrointestinal GVHD.

Peled, Jonathan U; Hanash, Alan M; Jenq, Robert R.

Blood; 128(20): 2395-2402, 2016 11 17.

Artículo en Inglés | MEDLINE | ID: mdl-27856471

13.

Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting.

He, Jie; Abdel-Wahab, Omar; Nahas, Michelle K; Wang, Kai; Rampal, Raajit K; Intlekofer, Andrew M; Patel, Jay; Krivstov, Andrei; Frampton, Garrett M; Young, Lauren E; Zhong, Shan; Bailey, Mark; White, Jared R; Roels, Steven; Deffenbaugh, Jason; Fichtenholtz, Alex; Brennan, Timothy; Rosenzweig, Mark; Pelak, Kimberly; Knapp, Kristina M; Brennan, Kristina W; Donahue, Amy L; Young, Geneva; Garcia, Lazaro; Beckstrom, Selmira T; Zhao, Mandy; White, Emily; Banning, Vera; Buell, Jamie; Iwanik, Kiel; Ross, Jeffrey S; Morosini, Deborah; Younes, Anas; Hanash, Alan M; Paietta, Elisabeth; Roberts, Kathryn; Mullighan, Charles; Dogan, Ahmet; Armstrong, Scott A; Mughal, Tariq; Vergilio, Jo-Anne; Labrecque, Elaine; Erlich, Rachel; Vietz, Christine; Yelensky, Roman; Stephens, Philip J; Miller, Vincent A; van den Brink, Marcel R M; Otto, Geoff A; Lipson, Doron.

Blood; 127(24): 3004-14, 2016 06 16.

Artículo en Inglés | MEDLINE | ID: mdl-26966091

14.

Does GVHD make amateurs out of professional APCs?

Hanash, Alan M.

Blood; 126(12): 1404-5, 2015 Sep 17.

Artículo en Inglés | MEDLINE | ID: mdl-26384284

15.

High day 28 ST2 levels predict for acute graft-versus-host disease and transplant-related mortality after cord blood transplantation.

Ponce, Doris M; Hilden, Patrick; Mumaw, Christen; Devlin, Sean M; Lubin, Marissa; Giralt, Sergio; Goldberg, Jenna D; Hanash, Alan; Hsu, Katharine; Jenq, Robert; Perales, Miguel-Angel; Sauter, Craig; van den Brink, Marcel R M; Young, James W; Brentjens, Renier; Kernan, Nancy A; Prockop, Susan E; O'Reilly, Richard J; Scaradavou, Andromachi; Paczesny, Sophie; Barker, Juliet N.

Blood; 125(1): 199-205, 2015 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-25377785

16.

BCL6 inhibition: a chronic GVHD twofer.

Vinci, Paola; Hanash, Alan M.

Blood; 133(1): 4-5, 2019 01 03.

Artículo en Inglés | MEDLINE | ID: mdl-30606808

17.

Association between Nondominant Unit Total Nucleated Cell Dose and Engraftment in Myeloablative Double-Unit Cord Blood Transplantation.

Purtill, Duncan; Stevens, Cladd E; Lubin, Marissa; Ponce, Doris; Hanash, Alan; Giralt, Sergio; Scaradavou, Andromachi; Young, James W; Barker, Juliet N.

Biol Blood Marrow Transplant; 21(11): 1981-4, 2015 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-26211983

18.

Intensified Mycophenolate Mofetil Dosing and Higher Mycophenolic Acid Trough Levels Reduce Severe Acute Graft-versus-Host Disease after Double-Unit Cord Blood Transplantation.

Harnicar, Stephen; Ponce, Doris M; Hilden, Patrick; Zheng, Junting; Devlin, Sean M; Lubin, Marissa; Pozotrigo, Melissa; Mathew, Sherry; Adel, Nelly; Kernan, Nancy A; O'Reilly, Richard; Prockop, Susan; Scaradavou, Andromachi; Hanash, Alan; Jenq, Robert; van den Brink, Marcel; Giralt, Sergio; Perales, Miguel A; Young, James W; Barker, Juliet N.

Biol Blood Marrow Transplant; 21(5): 920-5, 2015 May.

Artículo en Inglés | MEDLINE | ID: mdl-25687796

19.

Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host Disease.

Jenq, Robert R; Taur, Ying; Devlin, Sean M; Ponce, Doris M; Goldberg, Jenna D; Ahr, Katya F; Littmann, Eric R; Ling, Lilan; Gobourne, Asia C; Miller, Liza C; Docampo, Melissa D; Peled, Jonathan U; Arpaia, Nicholas; Cross, Justin R; Peets, Tatanisha K; Lumish, Melissa A; Shono, Yusuke; Dudakov, Jarrod A; Poeck, Hendrik; Hanash, Alan M; Barker, Juliet N; Perales, Miguel-Angel; Giralt, Sergio A; Pamer, Eric G; van den Brink, Marcel R M.

Biol Blood Marrow Transplant; 21(8): 1373-83, 2015 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-25977230

20.

The central nervous system is a target of acute graft versus host disease in mice.

Hartrampf, Steffen; Dudakov, Jarrod A; Johnson, Linda K; Smith, Odette M; Tsai, Jennifer; Singer, Natalie V; West, Mallory L; Hanash, Alan M; Albert, Michael H; Liu, Bingfang; Toth, Miklos; van den Brink, Marcel R M.

Blood; 121(10): 1906-10, 2013 Mar 07.

Artículo en Inglés | MEDLINE | ID: mdl-23299314

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