Detalles de la búsqueda
1.
SAR of L-ABBA analogs for GGT1 inhibitory activity and L-ABBA's effect on plasma cysteine and GSH species.
Bioorg Med Chem Lett;
92: 129406, 2023 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37423504
2.
Crystal structures of glutathione- and inhibitor-bound human GGT1: critical interactions within the cysteinylglycine binding site.
J Biol Chem;
296: 100066, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33187988
3.
Design and evaluation of novel analogs of 2-amino-4-boronobutanoic acid (ABBA) as inhibitors of human gamma-glutamyl transpeptidase.
Bioorg Med Chem;
73: 116986, 2022 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36208545
4.
Human γ-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS.
J Biol Chem;
290(28): 17576-86, 2015 Jul 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26013825
5.
Immunolabeling of gamma-glutamyl transferase 5 in normal human tissues reveals that expression and localization differ from gamma-glutamyl transferase 1.
Histochem Cell Biol;
143(5): 505-15, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25377544
6.
Novel insights into eukaryotic γ-glutamyltranspeptidase 1 from the crystal structure of the glutamate-bound human enzyme.
J Biol Chem;
288(44): 31902-13, 2013 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24047895
7.
Detection of distinct glycosylation patterns on human γ-glutamyl transpeptidase 1 using antibody-lectin sandwich array (ALSA) technology.
BMC Biotechnol;
14: 101, 2014 Dec 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-25479762
8.
Inhibition of human γ-glutamyl transpeptidase: development of more potent, physiologically relevant, uncompetitive inhibitors.
Biochem J;
450(3): 547-57, 2013 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23301618
9.
Autocatalytic cleavage of human gamma-glutamyl transpeptidase is highly dependent on N-glycosylation at asparagine 95.
J Biol Chem;
286(33): 28876-28888, 2011 Aug 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-21712391
10.
Divergent effects of compounds on the hydrolysis and transpeptidation reactions of γ-glutamyl transpeptidase.
J Enzyme Inhib Med Chem;
27(4): 476-89, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21864033
11.
Analysis of site-specific glycosylation of renal and hepatic γ-glutamyl transpeptidase from normal human tissue.
J Biol Chem;
285(38): 29511-24, 2010 Sep 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-20622017
12.
Gamma-glutamyl compounds: substrate specificity of gamma-glutamyl transpeptidase enzymes.
Anal Biochem;
414(2): 208-14, 2011 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21447318
13.
γ-Glutamyl transpeptidase is a heavily N-glycosylated heterodimer in HepG2 cells.
Arch Biochem Biophys;
504(2): 177-81, 2010 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20831856
14.
Structure of 6-diazo-5-oxo-norleucine-bound human gamma-glutamyl transpeptidase 1, a novel mechanism of inactivation.
Protein Sci;
26(6): 1196-1205, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28378915
15.
Sphingosine-1-phosphate lyase regulates sensitivity of human cells to select chemotherapy drugs in a p38-dependent manner.
Mol Cancer Res;
3(5): 287-96, 2005 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15886300
16.
Metabolism of cisplatin to a nephrotoxin.
Toxicology;
257(3): 174-5; author reply 176-7, 2009 Mar 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-19135119
17.
Gamma-glutamyl transpeptidase: redox regulation and drug resistance.
Adv Cancer Res;
122: 103-41, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24974180
18.
Human GGT2 does not autocleave into a functional enzyme: A cautionary tale for interpretation of microarray data on redox signaling.
Antioxid Redox Signal;
19(16): 1877-88, 2013 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23682772
19.
N-Acetylcysteine interacts with copper to generate hydrogen peroxide and selectively induce cancer cell death.
Cancer Lett;
298(2): 186-94, 2010 Dec 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-20667650
20.
A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase.
J Biol Chem;
284(14): 9059-65, 2009 Apr 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-19203993