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1.

Functional Characterization of Cardiac Actin Mutants Causing Hypertrophic (p.A295S) and Dilated Cardiomyopathy (p.R312H and p.E361G).

Hassoun, Roua; Erdmann, Constanze; Schmitt, Sebastian; Fujita-Becker, Setsuko; Mügge, Andreas; Schröder, Rasmus R; Geyer, Matthias; Borbor, Mina; Jaquet, Kornelia; Hamdani, Nazha; Mannherz, Hans Georg.

Int J Mol Sci; 23(8)2022 Apr 18.

Artículo en Inglés | MEDLINE | ID: mdl-35457283

2.

Cardiomyocyte Dysfunction in Inherited Cardiomyopathies.

Hassoun, Roua; Budde, Heidi; Mügge, Andreas; Hamdani, Nazha.

Int J Mol Sci; 22(20)2021 Oct 15.

Artículo en Inglés | MEDLINE | ID: mdl-34681814

3.

Genetic Restrictive Cardiomyopathy: Causes and Consequences-An Integrative Approach.

Cimiotti, Diana; Budde, Heidi; Hassoun, Roua; Jaquet, Kornelia.

Int J Mol Sci; 22(2)2021 Jan 08.

Artículo en Inglés | MEDLINE | ID: mdl-33429969

4.

De Novo Missense Mutations in TNNC1 and TNNI3 Causing Severe Infantile Cardiomyopathy Affect Myofilament Structure and Function and Are Modulated by Troponin Targeting Agents.

Hassoun, Roua; Budde, Heidi; Mannherz, Hans Georg; Lódi, Mária; Fujita-Becker, Setsuko; Laser, Kai Thorsten; Gärtner, Anna; Klingel, Karin; Möhner, Desirée; Stehle, Robert; Sultana, Innas; Schaaf, Thomas; Majchrzak, Mario; Krause, Verena; Herrmann, Christian; Nowaczyk, Marc M; Mügge, Andreas; Pfitzer, Gabriele; Schröder, Rasmus R; Hamdani, Nazha; Milting, Hendrik; Jaquet, Kornelia; Cimiotti, Diana.

Int J Mol Sci; 22(17)2021 Sep 06.

Artículo en Inglés | MEDLINE | ID: mdl-34502534

5.

Reorganization of the actin cytoskeleton during the formation of neutrophil extracellular traps (NETs).

Mannherz, Hans Georg; Budde, Heidi; Jarkas, Muhammad; Hassoun, Roua; Malek-Chudzik, Natalia; Mazur, Antonina J; Skuljec, Jelena; Pul, Refik; Napirei, Markus; Hamdani, Nazha.

Eur J Cell Biol; 103(2): 151407, 2024 Mar 26.

Artículo en Inglés | MEDLINE | ID: mdl-38555846

6.

Sex-specific cardiovascular remodeling leads to a divergent sex-dependent development of heart failure in aged hypertensive rats.

Kovács, Árpád; Zhazykbayeva, Saltanat; Herwig, Melissa; Fülöp, Gábor Á; Csípo, Tamás; Oláh, Nikolett; Hassoun, Roua; Budde, Heidi; Osman, Hersh; Kaçmaz, Mustafa; Jaquet, Kornelia; Priksz, Dániel; Juhász, Béla; Akin, Ibrahim; Papp, Zoltán; Schmidt, Wolfgang E; Mügge, Andreas; El-Battrawy, Ibrahim; Tóth, Attila; Hamdani, Nazha.

Geroscience; 2024 Apr 24.

Artículo en Inglés | MEDLINE | ID: mdl-38656649

7.

Oxidative stress and inflammation distinctly drive molecular mechanisms of diastolic dysfunction and remodeling in female and male heart failure with preserved ejection fraction rats.

Zhazykbayeva, Saltanat; Hassoun, Roua; Herwig, Melissa; Budde, Heidi; Kovács, Árpád; Mannherz, Hans Georg; El-Battrawy, Ibrahim; Tóth, Attila; Schmidt, Wolfgang E; Mügge, Andreas; Hamdani, Nazha.

Front Cardiovasc Med; 10: 1157398, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37363100

8.

Current Understanding of Molecular Pathophysiology of Heart Failure With Preserved Ejection Fraction.

Budde, Heidi; Hassoun, Roua; Mügge, Andreas; Kovács, Árpád; Hamdani, Nazha.

Front Physiol; 13: 928232, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-35874547

9.

Ca2+/calmodulin-dependent protein kinase II and protein kinase G oxidation contributes to impaired sarcomeric proteins in hypertrophy model.

Gömöri, Kamilla; Herwig, Melissa; Budde, Heidi; Hassoun, Roua; Mostafi, Nusratul; Zhazykbayeva, Saltanat; Sieme, Marcel; Modi, Suvasini; Szabados, Tamara; Pipis, Judit; Farkas-Morvay, Nikolett; Leprán, István; Ágoston, Gergely; Baczkó, István; Kovács, Árpád; Mügge, Andreas; Ferdinandy, Péter; Görbe, Anikó; Bencsik, Péter; Hamdani, Nazha.

ESC Heart Fail; 9(4): 2585-2600, 2022 08.

Artículo en Inglés | MEDLINE | ID: mdl-35584900

10.

Altered Cellular Protein Quality Control System Modulates Cardiomyocyte Function in Volume Overload-Induced Hypertrophy.

Gömöri, Kamilla; Herwig, Melissa; Hassoun, Roua; Budde, Heidi; Mostafi, Nusratul; Delalat, Simin; Modi, Suvasini; Begovic, Merima; Szabados, Tamara; Pipis, Judit; Farkas-Morvay, Nikolett; Leprán, István; Kovács, Árpád; Mügge, Andreas; Ferdinandy, Péter; Görbe, Anikó; Bencsik, Péter; Hamdani, Nazha.

Antioxidants (Basel); 11(11)2022 Nov 08.

Artículo en Inglés | MEDLINE | ID: mdl-36358581

11.

SARS-CoV-2 infects human cardiomyocytes promoted by inflammation and oxidative stress.

Tangos, Melina; Budde, Heidi; Kolijn, Detmar; Sieme, Marcel; Zhazykbayeva, Saltanat; Lódi, Mária; Herwig, Melissa; Gömöri, Kamilla; Hassoun, Roua; Robinson, Emma Louise; Meister, Toni Luise; Jaquet, Kornelia; Kovács, Árpád; Mustroph, Julian; Evert, Katja; Babel, Nina; Fagyas, Miklós; Lindner, Diana; Püschel, Klaus; Westermann, Dirk; Mannherz, Hans Georg; Paneni, Francesco; Pfaender, Stephanie; Tóth, Attila; Mügge, Andreas; Sossalla, Samuel; Hamdani, Nazha.

Int J Cardiol; 362: 196-205, 2022 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-35643215

12.

Integration of Cardiac Actin Mutants Causing Hypertrophic (p.A295S) and Dilated Cardiomyopathy (p.R312H and p.E361G) into Cellular Structures.

Erdmann, Constanze; Hassoun, Roua; Schmitt, Sebastian; Kikuti, Carlos; Houdusse, Anne; Mazur, Antonina J; Mügge, Andreas; Hamdani, Nazha; Geyer, Matthias; Jaquet, Kornelia; Mannherz, Hans Georg.

Antioxidants (Basel); 10(7)2021 Jul 05.

Artículo en Inglés | MEDLINE | ID: mdl-34356314

13.

Interventricular Differences of Signaling Pathways-Mediated Regulation of Cardiomyocyte Function in Response to High Oxidative Stress in the Post-Ischemic Failing Rat Heart.

Kovács, Árpád; Herwig, Melissa; Budde, Heidi; Delalat, Simin; Kolijn, Detmar; Bódi, Beáta; Hassoun, Roua; Tangos, Melina; Zhazykbayeva, Saltanat; Balogh, Ágnes; Czuriga, Dániel; Van Linthout, Sophie; Tschöpe, Carsten; Dhalla, Naranjan S; Mügge, Andreas; Tóth, Attila; Papp, Zoltán; Barta, Judit; Hamdani, Nazha.

Antioxidants (Basel); 10(6)2021 Jun 16.

Artículo en Inglés | MEDLINE | ID: mdl-34208541

14.

The Interplay between S-Glutathionylation and Phosphorylation of Cardiac Troponin I and Myosin Binding Protein C in End-Stage Human Failing Hearts.

Budde, Heidi; Hassoun, Roua; Tangos, Melina; Zhazykbayeva, Saltanat; Herwig, Melissa; Varatnitskaya, Marharyta; Sieme, Marcel; Delalat, Simin; Sultana, Innas; Kolijn, Detmar; Gömöri, Kamilla; Jarkas, Muhammad; Lódi, Mária; Jaquet, Kornelia; Kovács, Árpád; Mannherz, Hans Georg; Sequeira, Vasco; Mügge, Andreas; Leichert, Lars I; Sossalla, Samuel; Hamdani, Nazha.

Antioxidants (Basel); 10(7)2021 Jul 16.

Artículo en Inglés | MEDLINE | ID: mdl-34356367

15.

Stress activated signalling impaired protein quality control pathways in human hypertrophic cardiomyopathy.

Hassoun, Roua; Budde, Heidi; Zhazykbayeva, Saltanat; Herwig, Melissa; Sieme, Marcel; Delalat, Simin; Mostafi, Nusratul; Gömöri, Kamilla; Tangos, Melina; Jarkas, Muhammad; Pabel, Steffen; Bruckmüller, Stefanie; Skrygan, Marina; Lódi, Mária; Jaquet, Kornelia; Sequeira, Vasco; Gambichler, Thilo; Remedios, Cris Dos; Kovács, Árpád; Mannherz, Hans Georg; Mügge, Andreas; Sossalla, Samuel; Hamdani, Nazha.

Int J Cardiol; 344: 160-169, 2021 Dec 01.

Artículo en Inglés | MEDLINE | ID: mdl-34517018

16.

Inflammation in HFpEF: Crucial or Ancillary?

Hassoun, Roua; Hamdani, Nazha.

Circ Heart Fail; 16(8): e010887, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37497625

17.

Do they come together? Protein quality control, stress-activated signaling, and "sarcostat" in hypertrophic cardiomyopathy progression.

Hassoun, Roua; Budde, Heidi; Zhazykbayeva, Saltanat; Herwig, Melissa; Sieme, Marcel; Delalat, Simin; Mostafi, Nusratul; Gömöri, Kamilla; Tangos, Melina; Jarkas, Muhammad; Pabel, Steffen; Bruckmüller, Stefanie; Skrygan, Marina; Lódi, Mária; Jaquet, Kornelia; Sequeira, Vasco; Gambichler, Thilo; Remedios, Cris Dos; Kovács, Árpád; Mannherz, Hans Georg; Mügge, Andreas; Sossalla, Samuel; Hamdani, Nazha.

Int J Cardiol; 347: 44-45, 2022 Jan 15.

Artículo en Inglés | MEDLINE | ID: mdl-34767897

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