Detalles de la búsqueda
1.
Accelerated cell culture process development and characterization for cilgavimab/tixagevimab (AZD7442) for the prevention and treatment of COVID-19.
Biotechnol Bioeng;
2023 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36722717
2.
DetectIS: a pipeline to rapidly detect exogenous DNA integration sites using DNA or RNA paired-end sequencing data.
Bioinformatics;
37(22): 4230-4232, 2021 11 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33978747
3.
Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins.
Metab Eng;
72: 171-187, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35301123
4.
Systematic use of synthetic 5'-UTR RNA structures to tune protein translation improves yield and quality of complex proteins in mammalian cell factories.
Nucleic Acids Res;
48(20): e119, 2020 11 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33051690
5.
Targeted CHO cell engineering approaches can reduce HCP-related enzymatic degradation and improve mAb product quality.
Biotechnol Bioeng;
118(10): 3821-3831, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34125434
6.
A novel hydrogen peroxide evolved CHO host can improve the expression of difficult to express bispecific antibodies.
Biotechnol Bioeng;
118(6): 2326-2337, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33675232
7.
Whole synthetic pathway engineering of recombinant protein production.
Biotechnol Bioeng;
116(2): 375-387, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30345502
8.
In silico design of context-responsive mammalian promoters with user-defined functionality.
Nucleic Acids Res;
45(18): 10906-10919, 2017 Oct 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28977454
9.
Control of amino acid transport into Chinese hamster ovary cells.
Biotechnol Bioeng;
115(12): 2908-2929, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-29987891
10.
Interplay of heavy chain introns influences efficient transcript splicing and affects product quality of recombinant biotherapeutic antibodies from CHO cells.
MAbs;
15(1): 2242548, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37555672
11.
Next-generation cell line selection methodology leveraging data lakes, natural language generation and advanced data analytics.
Front Bioeng Biotechnol;
11: 1160223, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37342509
12.
CHO synthetic promoters improve expression and product quality of biotherapeutic proteins.
Biotechnol Prog;
39(5): e3348, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37114854
13.
Determination of Chinese hamster ovary cell line stability and recombinant antibody expression during long-term culture.
Biotechnol Bioeng;
109(8): 2093-103, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22896849
14.
Monoclonal Antibody Sequence Variants Disguised as Fragments: Identification, Characterization, and Their Removal by Purification Process Optimization.
J Pharm Sci;
111(11): 3009-3016, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35940243
15.
Mitochondrial membrane potential-enriched CHO host: a novel and powerful tool for improving biomanufacturing capability.
MAbs;
14(1): 2020081, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35030984
16.
Autophagy and intracellular product degradation genes identified by systems biology analysis reduce aggregation of bispecific antibody in CHO cells.
N Biotechnol;
68: 68-76, 2022 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-35123066
17.
Enhanced metabolism and negative regulation of ER stress support higher erythropoietin production in HEK293 cells.
Cell Rep;
39(11): 110936, 2022 06 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35705050
18.
Using participatory methods to examine policy and women prisoners' health.
Policy Polit Nurs Pract;
12(2): 119-25, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21903718
19.
Control of Multigene Expression Stoichiometry in Mammalian Cells Using Synthetic Promoters.
ACS Synth Biol;
10(5): 1155-1165, 2021 05 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-33939428
20.
Evolution from adherent to suspension: systems biology of HEK293 cell line development.
Sci Rep;
10(1): 18996, 2020 11 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33149219