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1.

Therapeutic activity of GARP:TGF-ß1 blockade in murine primary myelofibrosis.

Lecomte, Sara; Devreux, Julien; de Streel, Grégoire; van Baren, Nicolas; Havelange, Violaine; Schröder, David; Vaherto, Noora; Vanhaver, Christophe; Vanderaa, Christophe; Dupuis, Noémie; Pecquet, Christian; Coulie, Pierre G; Constantinescu, Stefan N; Lucas, Sophie.

Blood; 141(5): 490-502, 2023 02 02.

Artículo en Inglés | MEDLINE | ID: mdl-36322928

2.

Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms.

Pecquet, Christian; Papadopoulos, Nicolas; Balligand, Thomas; Chachoua, Ilyas; Tisserand, Amandine; Vertenoeil, Gaëlle; Nédélec, Audrey; Vertommen, Didier; Roy, Anita; Marty, Caroline; Nivarthi, Harini; Defour, Jean-Philippe; El-Khoury, Mira; Hug, Eva; Majoros, Andrea; Xu, Erica; Zagrijtschuk, Oleh; Fertig, Tudor E; Marta, Daciana S; Gisslinger, Heinz; Gisslinger, Bettina; Schalling, Martin; Casetti, Ilaria; Rumi, Elisa; Pietra, Daniela; Cavalloni, Chiara; Arcaini, Luca; Cazzola, Mario; Komatsu, Norio; Kihara, Yoshihiko; Sunami, Yoshitaka; Edahiro, Yoko; Araki, Marito; Lesyk, Roman; Buxhofer-Ausch, Veronika; Heibl, Sonja; Pasquier, Florence; Havelange, Violaine; Plo, Isabelle; Vainchenker, William; Kralovics, Robert; Constantinescu, Stefan N.

Blood; 141(8): 917-929, 2023 02 23.

Artículo en Inglés | MEDLINE | ID: mdl-36356299

3.

Phase 3 trial of gilteritinib plus azacitidine vs azacitidine for newly diagnosed FLT3mut+ AML ineligible for intensive chemotherapy.

Wang, Eunice S; Montesinos, Pau; Minden, Mark D; Lee, Je-Hwan; Heuser, Michael; Naoe, Tomoki; Chou, Wen-Chien; Laribi, Kamel; Esteve, Jordi; Altman, Jessica K; Havelange, Violaine; Watson, Anne-Marie; Gambacorti-Passerini, Carlo; Patkowska, Elzbieta; Liu, Shufang; Wu, Ruishan; Philipose, Nisha; Hill, Jason E; Gill, Stanley C; Rich, Elizabeth Shima; Tiu, Ramon V.

Blood; 140(17): 1845-1857, 2022 10 27.

Artículo en Inglés | MEDLINE | ID: mdl-35917453

4.

Gut microbiome alterations at acute myeloid leukemia diagnosis are associated with muscle weakness and anorexia.

Pötgens, Sarah A; Havelange, Violaine; Lecop, Sophie; Li, Fuyong; Neyrinck, Audrey M; Bindels, Florence; Neveux, Nathalie; Demoulin, Jean-Baptiste; Moors, Ine; Kerre, Tessa; Maertens, Johan; Walter, Jens; Schoemans, Hélène; Delzenne, Nathalie M; Bindels, Laure B.

Haematologica; 2024 Mar 28.

Artículo en Inglés | MEDLINE | ID: mdl-38546675

5.

Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia.

DiNardo, Courtney D; Jonas, Brian A; Pullarkat, Vinod; Thirman, Michael J; Garcia, Jacqueline S; Wei, Andrew H; Konopleva, Marina; Döhner, Hartmut; Letai, Anthony; Fenaux, Pierre; Koller, Elizabeth; Havelange, Violaine; Leber, Brian; Esteve, Jordi; Wang, Jianxiang; Pejsa, Vlatko; Hájek, Roman; Porkka, Kimmo; Illés, Árpád; Lavie, David; Lemoli, Roberto M; Yamamoto, Kazuhito; Yoon, Sung-Soo; Jang, Jun-Ho; Yeh, Su-Peng; Turgut, Mehmet; Hong, Wan-Jen; Zhou, Ying; Potluri, Jalaja; Pratz, Keith W.

N Engl J Med; 383(7): 617-629, 2020 08 13.

Artículo en Inglés | MEDLINE | ID: mdl-32786187

6.

miR-15a-5p and miR-21-5p contribute to chemoresistance in cytogenetically normal acute myeloid leukaemia by targeting PDCD4, ARL2 and BTG2.

Vandewalle, Virginie; Essaghir, Ahmed; Bollaert, Emeline; Lenglez, Sandrine; Graux, Carlos; Schoemans, Hélène; Saussoy, Pascale; Michaux, Lucienne; Valk, Peter J M; Demoulin, Jean-Baptiste; Havelange, Violaine.

J Cell Mol Med; 25(1): 575-585, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-33270982

7.

Molecular Minimal Residual Disease in Acute Myeloid Leukemia.

Jongen-Lavrencic, Mojca; Grob, Tim; Hanekamp, Diana; Kavelaars, François G; Al Hinai, Adil; Zeilemaker, Annelieke; Erpelinck-Verschueren, Claudia A J; Gradowska, Patrycja L; Meijer, Rosa; Cloos, Jacqueline; Biemond, Bart J; Graux, Carlos; van Marwijk Kooy, Marinus; Manz, Markus G; Pabst, Thomas; Passweg, Jakob R; Havelange, Violaine; Ossenkoppele, Gert J; Sanders, Mathijs A; Schuurhuis, Gerrit J; Löwenberg, Bob; Valk, Peter J M.

N Engl J Med; 378(13): 1189-1199, 2018 Mar 29.

Artículo en Inglés | MEDLINE | ID: mdl-29601269

8.

Azacitidine maintenance after intensive chemotherapy improves DFS in older AML patients.

Huls, Gerwin; Chitu, Dana A; Havelange, Violaine; Jongen-Lavrencic, Mojca; van de Loosdrecht, Arjan A; Biemond, Bart J; Sinnige, Harm; Hodossy, Beata; Graux, Carlos; Kooy, Rien van Marwijk; de Weerdt, Okke; Breems, Dimitri; Klein, Saskia; Kuball, Jürgen; Deeren, Dries; Terpstra, Wim; Vekemans, Marie-Christiane; Ossenkoppele, Gert J; Vellenga, Edo; Löwenberg, Bob.

Blood; 133(13): 1457-1464, 2019 03 28.

Artículo en Inglés | MEDLINE | ID: mdl-30630862

9.

Clinical outcomes in patients with Philadelphia chromosome-positive leukemia treated with ponatinib in routine clinical practice-data from a Belgian registry.

Devos, Timothy; Havelange, Violaine; Theunissen, Koen; Meers, Stef; Benghiat, Fleur Samantha; Gadisseur, Alain; Vanstraelen, Gaëtan; Vellemans, Hélène; Bailly, Benjamin; Granacher, Nikki; Lewalle, Philippe; De Becker, Ann; Van Eygen, Koen; Janssen, Mia; Triffet, Agnes; Vrelust, Inge; Deeren, Dries; Mazure, Dominiek; Bekaert, Julie; Beck, Michael; Selleslag, Dominik.

Ann Hematol; 100(7): 1723-1732, 2021 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-33942128

10.

MiR-15a-5p Confers Chemoresistance in Acute Myeloid Leukemia by Inhibiting Autophagy Induced by Daunorubicin.

Bollaert, Emeline; Claus, Melissa; Vandewalle, Virginie; Lenglez, Sandrine; Essaghir, Ahmed; Demoulin, Jean-Baptiste; Havelange, Violaine.

Int J Mol Sci; 22(10)2021 May 13.

Artículo en Inglés | MEDLINE | ID: mdl-34068078

11.

Blinatumomab for minimal residual disease in adults with B-cell precursor acute lymphoblastic leukemia.

Gökbuget, Nicola; Dombret, Hervé; Bonifacio, Massimiliano; Reichle, Albrecht; Graux, Carlos; Faul, Christoph; Diedrich, Helmut; Topp, Max S; Brüggemann, Monika; Horst, Heinz-August; Havelange, Violaine; Stieglmaier, Julia; Wessels, Hendrik; Haddad, Vincent; Benjamin, Jonathan E; Zugmaier, Gerhard; Nagorsen, Dirk; Bargou, Ralf C.

Blood; 131(14): 1522-1531, 2018 04 05.

Artículo en Inglés | MEDLINE | ID: mdl-29358182

12.

Jaundice with severe leucocytosis.

Haxhe, Sarah; Baldin, Pamela; Trefois, Pierre; Havelange, Violaine; Lanthier, Nicolas.

J Hepatol; 80(3): e103-e105, 2024 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-38368018

13.

The 2 faces of ERK2 in MPNs.

Havelange, Violaine; Constantinescu, Stefan N.

Blood; 140(4): 298-300, 2022 07 28.

Artículo en Inglés | MEDLINE | ID: mdl-35900786

14.

Therapeutic value of clofarabine in younger and middle-aged (18-65 years) adults with newly diagnosed AML.

Löwenberg, Bob; Pabst, Thomas; Maertens, Johan; van Norden, Yvette; Biemond, Bart J; Schouten, Harry C; Spertini, Olivier; Vellenga, Edo; Graux, Carlos; Havelange, Violaine; de Greef, Georgine E; de Weerdt, Okke; Legdeur, Marie-Cecile J C; Kuball, Juergen; Kooy, Marinus van Marwijk; Gjertsen, Bjorn T; Jongen-Lavrencic, Mojca; van de Loosdrecht, Arjan A; van Lammeren-Venema, Daniëlle; Hodossy, Beata; Breems, Dimitri A; Chalandon, Yves; Passweg, Jakob; Valk, Peter J M; Manz, Markus G; Ossenkoppele, Gert J.

Blood; 129(12): 1636-1645, 2017 Mar 23.

Artículo en Inglés | MEDLINE | ID: mdl-28049642

15.

Interruption or Discontinuation of Tyrosine Kinase Inhibitor Treatment in Chronic Myeloid Leukaemia: A Retrospective Cohort Study (SPARKLE) in Belgium.

Devos, Timothy; Verhoef, Gregor; Steel, Eva; Mazure, Dominiek; Lewalle, Philippe; Bron, Dominique; Berneman, Zwi; Benghiat, Fleur Samantha; Mineur, Philippe; Theunissen, Koen; Zachée, Pierre; Doyen, Chantal; Put, Natalie; Lejeune, Marie; Van Eygen, Koen; Havelange, Violaine; Reusens, Michael; Pluymers, Wim; Peeters, Karen.

Acta Haematol; 142(4): 197-207, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-31163431

16.

Molecular pathogenesis of myeloproliferative neoplasms: Where do we stand in 2023?

Havelange, Violaine; Constantinescu, Stefan N.

Am J Hematol; 98(10): 1512-1516, 2023 10.

Artículo en Inglés | MEDLINE | ID: mdl-37635451

17.

Genetic differences between paediatric and adult Burkitt lymphomas.

Havelange, Violaine; Pepermans, Xavier; Ameye, Geneviève; Théate, Ivan; Callet-Bauchu, Evelyne; Barin, Carole; Penther, Dominique; Lippert, Eric; Michaux, Lucienne; Mugneret, Francine; Dastugue, Nicole; Raphaël, Martine; Vikkula, Miikka; Poirel, Hélène A.

Br J Haematol; 173(1): 137-44, 2016 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-26887776

18.

Implications of the miR-10 family in chemotherapy response of NPM1-mutated AML.

Havelange, Violaine; Ranganathan, Parvathi; Geyer, Susan; Nicolet, Deedra; Huang, Xiaomeng; Yu, Xueyan; Volinia, Stefano; Kornblau, Steven M; Andreeff, Michael; Croce, Carlo M; Marcucci, Guido; Bloomfield, Clara D; Garzon, Ramiro.

Blood; 123(15): 2412-5, 2014 Apr 10.

Artículo en Inglés | MEDLINE | ID: mdl-24596420

19.

Vosaroxin plus cytarabine versus placebo plus cytarabine in patients with first relapsed or refractory acute myeloid leukaemia (VALOR): a randomised, controlled, double-blind, multinational, phase 3 study.

Ravandi, Farhad; Ritchie, Ellen K; Sayar, Hamid; Lancet, Jeffrey E; Craig, Michael D; Vey, Norbert; Strickland, Stephen A; Schiller, Gary J; Jabbour, Elias; Erba, Harry P; Pigneux, Arnaud; Horst, Heinz-August; Recher, Christian; Klimek, Virginia M; Cortes, Jorge; Roboz, Gail J; Odenike, Olatoyosi; Thomas, Xavier; Havelange, Violaine; Maertens, Johan; Derigs, Hans-Günter; Heuser, Michael; Damon, Lloyd; Powell, Bayard L; Gaidano, Gianluca; Carella, Angelo-Michele; Wei, Andrew; Hogge, Donna; Craig, Adam R; Fox, Judith A; Ward, Renee; Smith, Jennifer A; Acton, Gary; Mehta, Cyrus; Stuart, Robert K; Kantarjian, Hagop M.

Lancet Oncol; 16(9): 1025-1036, 2015 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-26234174

20.

Cooccurring JAK2 V617F and R1063H mutations increase JAK2 signaling and neutrophilia in myeloproliferative neoplasms.

Mambet, Cristina; Babosova, Olga; Defour, Jean-Philippe; Leroy, Emilie; Necula, Laura; Stanca, Oana; Tatic, Aurelia; Berbec, Nicoleta; Coriu, Daniel; Belickova, Monika; Kralova, Barbora; Lanikova, Lucie; Vesela, Jitka; Pecquet, Christian; Saussoy, Pascale; Havelange, Violaine; Diaconu, Carmen C; Divoky, Vladimir; Constantinescu, Stefan N.

Blood; 132(25): 2695-2699, 2018 12 20.

Artículo en Inglés | MEDLINE | ID: mdl-30377194

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