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1.

Internally tagged Vps10p-domain receptors reveal uptake of the neurotrophin BDNF.

Klein, Marcel; Failla, Antonio Virgilio; Hermey, Guido.

J Biol Chem; 299(10): 105216, 2023 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-37660918

2.

The Batten disease protein CLN3 is important for stress granules dynamics and translational activity.

Relton, Emily L; Roth, Nicolas J; Yasa, Seda; Kaleem, Abuzar; Hermey, Guido; Minnis, Christopher J; Mole, Sara E; Shelkovnikova, Tatyana; Lefrancois, Stephane; McCormick, Peter J; Locker, Nicolas.

J Biol Chem; 299(5): 104649, 2023 05.

Artículo en Inglés | MEDLINE | ID: mdl-36965618

3.

CLN3 regulates endosomal function by modulating Rab7A-effector interactions.

Yasa, Seda; Modica, Graziana; Sauvageau, Etienne; Kaleem, Abuzar; Hermey, Guido; Lefrancois, Stephane.

J Cell Sci; 133(6)2020 03 16.

Artículo en Inglés | MEDLINE | ID: mdl-32034082

4.

SORCS1 and SORCS3 control energy balance and orexigenic peptide production.

Subkhangulova, Aygul; Malik, Anna R; Hermey, Guido; Popp, Oliver; Dittmar, Gunnar; Rathjen, Thomas; Poy, Matthew N; Stumpf, Alexander; Beed, Prateep Sanker; Schmitz, Dietmar; Breiderhoff, Tilman; Willnow, Thomas E.

EMBO Rep; 19(4)2018 04.

Artículo en Inglés | MEDLINE | ID: mdl-29440124

5.

Amyloidosis causes downregulation of SorLA, SorCS1 and SorCS3 expression in mice.

Hermey, Guido; Hoffmeister-Ullerich, Sabine A; Merz, Barbara; Groß, Dagmar; Kuhl, Dietmar; Kins, Stefan.

Biol Chem; 400(9): 1181-1189, 2019 08 27.

Artículo en Inglés | MEDLINE | ID: mdl-31095505

6.

Revisiting the neuronal localization and trafficking of CLN3 in juvenile neuronal ceroid lipofuscinosis.

Oetjen, Sandra; Kuhl, Dietmar; Hermey, Guido.

J Neurochem; 139(3): 456-470, 2016 11.

Artículo en Inglés | MEDLINE | ID: mdl-27453211

7.

SorCS1 variants and amyloid precursor protein (APP) are co-transported in neurons but only SorCS1c modulates anterograde APP transport.

Hermey, Guido; Schmidt, Nadine; Bluhm, Björn; Mensching, Daniel; Ostermann, Kristina; Rupp, Carsten; Kuhl, Dietmar; Kins, Stefan.

J Neurochem; 135(1): 60-75, 2015 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-26119586

8.

Human sorCS1 binds sortilin and hampers its cellular functions.

Larsen, Jakob Vejby; Hermey, Guido; Sørensen, Esben Skipper; Prabakaran, Thaneas; Christensen, Erik Ilsø; Gliemann, Jørgen; Madsen, Peder; Petersen, Claus Munck.

Biochem J; 457(2): 277-88, 2014 Jan 15.

Artículo en Inglés | MEDLINE | ID: mdl-24128306

9.

Converging links between adult-onset neurodegenerative Alzheimer's disease and early life neurodegenerative neuronal ceroid lipofuscinosis?

Klein, Marcel; Hermey, Guido.

Neural Regen Res; 18(7): 1463-1471, 2023 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-36571343

10.

The adaptor protein PICK1 targets the sorting receptor SorLA.

Binkle, Lars; Klein, Marcel; Borgmeyer, Uwe; Kuhl, Dietmar; Hermey, Guido.

Mol Brain; 15(1): 18, 2022 02 19.

Artículo en Inglés | MEDLINE | ID: mdl-35183222

11.

Converging roles of PSENEN/PEN2 and CLN3 in the autophagy-lysosome system.

Klein, Marcel; Kaleem, Abuzar; Oetjen, Sandra; Wünkhaus, Daniela; Binkle, Lars; Schilling, Sandra; Gjorgjieva, Milena; Scholz, Ralf; Gruber-Schoffnegger, Doris; Storch, Stephan; Kins, Stefan; Drewes, Gerard; Hoffmeister-Ullerich, Sabine; Kuhl, Dietmar; Hermey, Guido.

Autophagy; 18(9): 2068-2085, 2022 09.

Artículo en Inglés | MEDLINE | ID: mdl-34964690

12.

TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease.

Scotto Rosato, Anna; Krogsaeter, Einar K; Jaslan, Dawid; Abrahamian, Carla; Montefusco, Sandro; Soldati, Chiara; Spix, Barbara; Pizzo, Maria Teresa; Grieco, Giuseppina; Böck, Julia; Wyatt, Amanda; Wünkhaus, Daniela; Passon, Marcel; Stieglitz, Marc; Keller, Marco; Hermey, Guido; Markmann, Sandra; Gruber-Schoffnegger, Doris; Cotman, Susan; Johannes, Ludger; Crusius, Dennis; Boehm, Ulrich; Wahl-Schott, Christian; Biel, Martin; Bracher, Franz; De Leonibus, Elvira; Polishchuk, Elena; Medina, Diego L; Paquet, Dominik; Grimm, Christian.

EMBO Mol Med; 14(9): e15377, 2022 09 07.

Artículo en Inglés | MEDLINE | ID: mdl-35929194

13.

Different motifs regulate trafficking of SorCS1 isoforms.

Nielsen, Morten S; Keat, Sady J; Hamati, Jida W; Madsen, Peder; Gutzmann, Jakob J; Engelsberg, Arne; Pedersen, Karen M; Gustafsen, Camilla; Nykjaer, Anders; Gliemann, Jørgen; Hermans-Borgmeyer, Irm; Kuhl, Dietmar; Petersen, Claus M; Hermey, Guido.

Traffic; 9(6): 980-94, 2008 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-18315530

14.

Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.

Nielsen, Morten S; Gustafsen, Camilla; Madsen, Peder; Nyengaard, Jens R; Hermey, Guido; Bakke, Oddmund; Mari, Muriel; Schu, Peter; Pohlmann, Regina; Dennes, André; Petersen, Claus M.

Mol Cell Biol; 27(19): 6842-51, 2007 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-17646382

15.

The Vps10p-domain receptor family.

Hermey, Guido.

Cell Mol Life Sci; 66(16): 2677-89, 2009 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-19434368

16.

Neuronal activity regulates alternative exon usage.

Denkena, Johanna; Zaisser, Andrea; Merz, Barbara; Klinger, Bertram; Kuhl, Dietmar; Blüthgen, Nils; Hermey, Guido.

Mol Brain; 13(1): 148, 2020 11 10.

Artículo en Inglés | MEDLINE | ID: mdl-33172478

17.

Trafficking in Alzheimer's Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin.

Eggert, Simone; Thomas, Carolin; Kins, Stefan; Hermey, Guido.

Mol Neurobiol; 55(7): 5809-5829, 2018 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-29079999

18.

Targeting amyloid precursor protein.

Hermey, Guido.

Ann Neurol; 69(1): 8-10, 2011 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-21280070

19.

Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members.

Hermey, Guido; Sjøgaard, Susanne S; Petersen, Claus Munck; Nykjaer, Anders; Gliemann, Jørgen.

Biochem J; 395(2): 285-93, 2006 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-16393139

20.

Deciphering the transcriptomic signature of synaptic activity.

Hermey, Guido.

Neural Regen Res; 17(1): 82-84, 2022 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-34100431

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Internally tagged Vps10p-domain receptors reveal uptake of the neurotrophin BDNF.

The Batten disease protein CLN3 is important for stress granules dynamics and translational activity.

CLN3 regulates endosomal function by modulating Rab7A-effector interactions.

SORCS1 and SORCS3 control energy balance and orexigenic peptide production.

Amyloidosis causes downregulation of SorLA, SorCS1 and SorCS3 expression in mice.

Revisiting the neuronal localization and trafficking of CLN3 in juvenile neuronal ceroid lipofuscinosis.

SorCS1 variants and amyloid precursor protein (APP) are co-transported in neurons but only SorCS1c modulates anterograde APP transport.

Human sorCS1 binds sortilin and hampers its cellular functions.

Converging links between adult-onset neurodegenerative Alzheimer's disease and early life neurodegenerative neuronal ceroid lipofuscinosis?

The adaptor protein PICK1 targets the sorting receptor SorLA.

Converging roles of PSENEN/PEN2 and CLN3 in the autophagy-lysosome system.

TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease.

Different motifs regulate trafficking of SorCS1 isoforms.

Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.

The Vps10p-domain receptor family.

Neuronal activity regulates alternative exon usage.

Trafficking in Alzheimer's Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin.

Targeting amyloid precursor protein.

Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members.

Deciphering the transcriptomic signature of synaptic activity.