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1.
Hherisomes, Hedgehog specialized recycling endosomes, are required for high level Hedgehog signaling and tissue growth.
J Cell Sci;
134(10)2021 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34028543
2.
Unravelling Mechanisms of Doxorubicin-Induced Toxicity in 3D Human Intestinal Organoids.
Int J Mol Sci;
23(3)2022 Jan 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35163210
3.
A Transcriptomic Approach to Elucidate the Mechanisms of Gefitinib-Induced Toxicity in Healthy Human Intestinal Organoids.
Int J Mol Sci;
23(4)2022 Feb 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-35216325
4.
New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids.
Arch Toxicol;
95(8): 2691-2718, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34151400
5.
High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities.
Arch Toxicol;
91(3): 1367-1383, 2017 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-27358234
6.
Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity.
Arch Toxicol;
90(5): 1163-79, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26026609
7.
Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling.
Mol Cancer;
14: 147, 2015 Jul 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-26227951
8.
Quantitative high content imaging of cellular adaptive stress response pathways in toxicity for chemical safety assessment.
Chem Res Toxicol;
27(3): 338-55, 2014 Mar 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-24450961
9.
A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies.
Arch Toxicol;
88(5): 1083-95, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24599296
10.
The nuclear factor κB family member RelB facilitates apoptosis of renal epithelial cells caused by cisplatin/tumor necrosis factor α synergy by suppressing an epithelial to mesenchymal transition-like phenotypic switch.
Mol Pharmacol;
84(1): 128-38, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23625948
11.
AMAP, the alleged non-toxic isomer of acetaminophen, is toxic in rat and human liver.
Arch Toxicol;
87(1): 155-65, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22914986
12.
Drosophila Squid/hnRNP helps Dynein switch from a gurken mRNA transport motor to an ultrastructural static anchor in sponge bodies.
Dev Cell;
13(4): 523-38, 2007 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17925228
13.
The golgi comprises a paired stack that is separated at G2 by modulation of the actin cytoskeleton through Abi and Scar/WAVE.
Dev Cell;
12(6): 901-15, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17543863
14.
Examination of the cytotoxic and embryotoxic potential and underlying mechanisms of next-generation synthetic trioxolane and tetraoxane antimalarials.
Mol Med;
18: 1045-55, 2012 Sep 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-22669474
15.
Diclofenac inhibits tumor necrosis factor-α-induced nuclear factor-κB activation causing synergistic hepatocyte apoptosis.
Hepatology;
53(6): 2027-41, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21433042
16.
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors.
Nat Cancer;
3(4): 418-436, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35469014
17.
Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy.
Sci Rep;
11(1): 7259, 2021 03 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-33790333
18.
3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors.
PLoS One;
15(8): e0235319, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32810173
19.
Hydrophilic Auristatin Glycoside Payload Enables Improved Antibody-Drug Conjugate Efficacy and Biocompatibility.
Antibodies (Basel);
7(2)2018 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-31544867
20.
mRNA localization and ER-based protein sorting mechanisms dictate the use of transitional endoplasmic reticulum-golgi units involved in gurken transport in Drosophila oocytes.
Mol Biol Cell;
15(12): 5306-17, 2004 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-15385627