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1.

Antitumor efficacy and safety of unedited autologous CD5.CAR T cells in relapsed/refractory mature T-cell lymphomas.

Hill, LaQuisa C; Rouce, Rayne H; Wu, Mengfen J; Wang, Tao; Ma, Royce; Zhang, Huimin; Mehta, Birju; Lapteva, Natalia; Mei, Zhuyong; Smith, Tyler S; Yang, Lina; Srinivasan, Madhuwanti; Burkhardt, Phillip M; Ramos, Carlos A; Lulla, Premal; Arredondo, Martha; Grilley, Bambi; Heslop, Helen E; Brenner, Malcolm K; Mamonkin, Maksim.

Blood; 143(13): 1231-1241, 2024 Mar 28.

Artículo en Inglés | MEDLINE | ID: mdl-38145560

2.

Engineering T cells to suppress acute GVHD and leukemia relapse after allogeneic hematopoietic stem cell transplantation.

Mo, Feiyan; Watanabe, Norihiro; Omdahl, Kayleigh I; Burkhardt, Phillip M; Ding, Xiaoyun; Hayase, Eiko; Panoskaltsis-Mortari, Angela; Jenq, Robert R; Heslop, Helen E; Kean, Leslie S; Brenner, Malcolm K; Tkachev, Victor; Mamonkin, Maksim.

Blood; 141(10): 1194-1208, 2023 03 09.

Artículo en Inglés | MEDLINE | ID: mdl-36044667

3.

Bispecific Antibodies and Autologous Chimeric Antigen Receptor T cell therapies for Treatment of Hematological Malignancies.

Al Hadidi, Samer; Heslop, Helen E; Brenner, Malcolm K; Suzuki, Masataka.

Mol Ther; 2024 May 30.

Artículo en Inglés | MEDLINE | ID: mdl-38822527

4.

Donor-derived multiple leukemia antigen-specific T-cell therapy to prevent relapse after transplant in patients with ALL.

Naik, Swati; Vasileiou, Spyridoula; Tzannou, Ifigeneia; Kuvalekar, Manik; Watanabe, Ayumi; Robertson, Catherine; Lapteva, Natalia; Tao, Wang; Wu, Mengfen; Grilley, Bambi; Carrum, George; Kamble, Rammurti T; Hill, LaQuisa; Krance, Robert A; Martinez, Caridad; Tewari, Priti; Omer, Bilal; Gottschalk, Stephen; Heslop, Helen E; Brenner, Malcom K; Rooney, Cliona M; Vera, Juan F; Leen, Ann M; Lulla, Premal D.

Blood; 139(17): 2706-2711, 2022 04 28.

Artículo en Inglés | MEDLINE | ID: mdl-35134127

5.

Long-term follow-up for the development of subsequent malignancies in patients treated with genetically modified IECs.

Steffin, David H M; Muhsen, Ibrahim N; Hill, LaQuisa C; Ramos, Carlos A; Ahmed, Nabil; Hegde, Meenakshi; Wang, Tao; Wu, Mengfen; Gottschalk, Stephen; Whittle, Sarah B; Lulla, Premal D; Mamonkin, Maksim; Omer, Bilal; Rouce, Rayne H; Heczey, Andras; Metelitsa, Leonid S; Grilley, Bambi J; Robertson, Catherine; Torrano, Virginia; Lapteva, Natalia; Gee, Adrian P; Rooney, Cliona M; Brenner, Malcolm K; Heslop, Helen E.

Blood; 140(1): 16-24, 2022 07 07.

Artículo en Inglés | MEDLINE | ID: mdl-35325065

6.

Human platelet lysate enhances in vivo activity of CAR-VÎ´2 T cells by reducing cellular senescence and apoptosis.

Mo, Feiyan; Tsai, Chiou-Tsun; Zheng, Rong; Cheng, Chonghui; Heslop, Helen E; Brenner, Malcolm K; Mamonkin, Maksim; Watanabe, Norihiro.

Cytotherapy; 2024 Mar 12.

Artículo en Inglés | MEDLINE | ID: mdl-38506769

7.

Incipient clonal hematopoiesis is accelerated following CD30.CAR-T therapy.

Kapadia, Chiraag D; Rosas, Gerardo; Thakkar, Sachin G; Wu, Mengfen; Torrano, Virginia; Wang, Tao; Grilley, Bambi J; Heslop, Helen E; Ramos, Carlos A; Goodell, Margaret A; Lulla, Premal D.

Cytotherapy; 26(3): 261-265, 2024 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-38149948

8.

Prolonged cytopenias after immune effector cell therapy and lymphodepletion in patients with leukemia, lymphoma and solid tumors.

Miller, Anne; Daum, Rachel; Wang, Tao; Wu, Mengfen; Tat, Candise; Pfeiffer, Thomas; Navai, Shoba; Heczey, Andras; Hegde, Meenakshi; Ahmed, Nabil; Whittle, Sarah B; Hill, LaQuisa; Martinez, Caridad; Krance, Robert; Ramos, Carlos A; Rouce, Rayne H; Lulla, Premal; Heslop, Helen E; Omer, Bilal; Shekar, Meghan.

Cytotherapy; 2024 May 08.

Artículo en Inglés | MEDLINE | ID: mdl-38819365

9.

Taking T-Cell Oncotherapy Off-the-Shelf.

Mo, Feiyan; Mamonkin, Maksim; Brenner, Malcolm K; Heslop, Helen E.

Trends Immunol; 42(3): 261-272, 2021 03.

Artículo en Inglés | MEDLINE | ID: mdl-33536140

10.

Feasibility and preclinical efficacy of CD7-unedited CD7 CAR T cells for T cell malignancies.

Watanabe, Norihiro; Mo, Feiyan; Zheng, Rong; Ma, Royce; Bray, Vanesa C; van Leeuwen, Dayenne G; Sritabal-Ramirez, Juntima; Hu, Hongxiang; Wang, Sha; Mehta, Birju; Srinivasan, Madhuwanti; Scherer, Lauren D; Zhang, Huimin; Thakkar, Sachin G; Hill, LaQuisa C; Heslop, Helen E; Cheng, Chonghui; Brenner, Malcolm K; Mamonkin, Maksim.

Mol Ther; 31(1): 24-34, 2023 01 04.

Artículo en Inglés | MEDLINE | ID: mdl-36086817

11.

Replication competent retrovirus testing (RCR) in the National Gene Vector Biorepository: No evidence of RCR in 1,595 post-treatment peripheral blood samples obtained from 60 clinical trials.

Cornetta, Kenneth; Yao, Jing; House, Kimberley; Duffy, Lisa; Adusumilli, Prasad S; Beyer, Rachel; Booth, Claire; Brenner, Malcolm; Curran, Kevin; Grilley, Bambi; Heslop, Helen; Hinrichs, Christian S; Kaplan, Rosandra N; Kiem, Hans-Peter; Kochenderfer, James; Kohn, Donald B; Mailankody, Sham; Norberg, Scott M; O'Cearbhaill, Roisin E; Pappas, Jennifer; Park, Jae; Ramos, Carlos; Ribas, Antonio; Rivière, Isabelle; Rosenberg, Steven A; Sauter, Craig; Shah, Nirali N; Slovin, Susan F; Thrasher, Adrian; Williams, David A; Lin, Tsai-Yu.

Mol Ther; 31(3): 801-809, 2023 03 01.

Artículo en Inglés | MEDLINE | ID: mdl-36518078

12.

Moving CAR-Ts to the outpatient clinic.

Llaurador, Gabriela A; Heslop, Helen E; Steffin, David H.

Br J Haematol; 203(4): 507-508, 2023 11.

Artículo en Inglés | MEDLINE | ID: mdl-37751752

13.

Clinical effects of administering leukemia-specific donor T cells to patients with AML/MDS after allogeneic transplant.

Lulla, Premal D; Naik, Swati; Vasileiou, Spyridoula; Tzannou, Ifigeneia; Watanabe, Ayumi; Kuvalekar, Manik; Lulla, Suhasini; Carrum, George; Ramos, Carlos A; Kamble, Rammurti; Hill, LaQuisa; Randhawa, Jasleen; Gottschalk, Stephen; Krance, Robert; Wang, Tao; Wu, Mengfen; Robertson, Catherine; Gee, Adrian P; Chung, Betty; Grilley, Bambi; Brenner, Malcolm K; Heslop, Helen E; Vera, Juan F; Leen, Ann M.

Blood; 137(19): 2585-2597, 2021 05 13.

Artículo en Inglés | MEDLINE | ID: mdl-33270816

14.

Allogeneic, off-the-shelf, SARS-CoV-2-specific T cells (ALVR109) for the treatment of COVID-19 in high-risk patients.

Vasileiou, Spyridoula; Hill, LaQuisa; Kuvalekar, Manik; Workineh, Aster G; Watanabe, Ayumi; Velazquez, Yovana; Lulla, Suhasini; Mooney, Kimberly; Lapteva, Natalia; Grilley, Bambi J; Heslop, Helen E; Rooney, Cliona M; Brenner, Malcolm K; Eagar, Todd N; Carrum, George; Grimes, Kevin A; Leen, Ann M; Lulla, Premal.

Haematologica; 108(7): 1840-1850, 2023 Jul 01.

Artículo en Inglés | MEDLINE | ID: mdl-36373249

15.

Genetic errors of immunity distinguish pediatric nonmalignant lymphoproliferative disorders.

Forbes, Lisa R; Eckstein, Olive S; Gulati, Nitya; Peckham-Gregory, Erin C; Ozuah, Nmazuo W; Lubega, Joseph; El-Mallawany, Nader K; Agrusa, Jennifer E; Poli, M Cecilia; Vogel, Tiphanie P; Chaimowitz, Natalia S; Rider, Nicholas L; Mace, Emily M; Orange, Jordan S; Caldwell, Jason W; Aldave-Becerra, Juan C; Jolles, Stephen; Saettini, Francesco; Chong, Hey J; Stray-Pedersen, Asbjorg; Heslop, Helen E; Kamdar, Kala Y; Rouce, R Helen; Muzny, Donna M; Jhangiani, Shalini N; Gibbs, Richard A; Coban-Akdemir, Zeynep H; Lupski, James R; McClain, Kenneth L; Allen, Carl E; Chinn, Ivan K.

J Allergy Clin Immunol; 149(2): 758-766, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-34329649

16.

Data mining for second malignancies after CAR-T.

Heslop, Helen E.

Blood; 143(20): 2023-2024, 2024 May 16.

Artículo en Inglés | MEDLINE | ID: mdl-38753361

17.

Autologous EBV-specific T cell treatment results in sustained responses in patients with advanced extranodal NK/T lymphoma: results of a multicenter study.

Kim, Won Seog; Oki, Yasuhiro; Kim, Seok Jin; Yoon, Sang Eun; Ardeshna, Kirit M; Lin, Yi; Ruan, Jia; Porcu, Pierluigi; Brammer, Jonathan E; Jacobsen, Eric D; Yoon, Dok Hyun; Suh, Cheolwon; Suarez, Felipe; Radford, John; Budde, Lihua E; Kim, Jin Seok; Bachy, Emmanuel; Lee, Hun Ju; Bollard, Catherine M; Jaccard, Arnaud; Kang, Hye Jin; Inman, Shannon; Murray, Maryann; Combs, Katherin E; Lee, Daniel Y; Advani, Ranjana; Gunter, Kurt C; Rooney, Cliona M; Heslop, Helen E.

Ann Hematol; 100(10): 2529-2539, 2021 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-34304287

18.

Priorities for Improving Outcomes for Nonmalignant Blood Diseases: A Report from the Blood and Marrow Transplant Clinical Trials Network.

Levine, John E; Antin, Joseph H; Allen, Carl E; Burroughs, Lauri M; Cooke, Kenneth R; Devine, Steven; Heslop, Helen; Nakamura, Ryotaro; Talano, Julie An; Yanik, Gregory; DiFronzo, Nancy.

Biol Blood Marrow Transplant; 26(5): e94-e100, 2020 05.

Artículo en Inglés | MEDLINE | ID: mdl-32035274

19.

Introduction to a review series on banked allogeneic immune effector cells.

Heslop, Helen E.

Blood; 141(8): 811-812, 2023 02 23.

Artículo en Inglés | MEDLINE | ID: mdl-36608323

20.

Introduction to a How I Treat series on emergent CAR T-cell toxicities.

Heslop, Helen E.

Blood; 141(20): 2405-2407, 2023 05 18.

Artículo en Inglés | MEDLINE | ID: mdl-36928098

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Antitumor efficacy and safety of unedited autologous CD5.CAR T cells in relapsed/refractory mature T-cell lymphomas.

Engineering T cells to suppress acute GVHD and leukemia relapse after allogeneic hematopoietic stem cell transplantation.

Bispecific Antibodies and Autologous Chimeric Antigen Receptor T cell therapies for Treatment of Hematological Malignancies.

Donor-derived multiple leukemia antigen-specific T-cell therapy to prevent relapse after transplant in patients with ALL.

Long-term follow-up for the development of subsequent malignancies in patients treated with genetically modified IECs.

Human platelet lysate enhances in vivo activity of CAR-VÎ´2 T cells by reducing cellular senescence and apoptosis.

Incipient clonal hematopoiesis is accelerated following CD30.CAR-T therapy.

Prolonged cytopenias after immune effector cell therapy and lymphodepletion in patients with leukemia, lymphoma and solid tumors.

Taking T-Cell Oncotherapy Off-the-Shelf.

Feasibility and preclinical efficacy of CD7-unedited CD7 CAR T cells for T cell malignancies.

Replication competent retrovirus testing (RCR) in the National Gene Vector Biorepository: No evidence of RCR in 1,595 post-treatment peripheral blood samples obtained from 60 clinical trials.

Moving CAR-Ts to the outpatient clinic.

Clinical effects of administering leukemia-specific donor T cells to patients with AML/MDS after allogeneic transplant.

Allogeneic, off-the-shelf, SARS-CoV-2-specific T cells (ALVR109) for the treatment of COVID-19 in high-risk patients.

Genetic errors of immunity distinguish pediatric nonmalignant lymphoproliferative disorders.

Data mining for second malignancies after CAR-T.

Autologous EBV-specific T cell treatment results in sustained responses in patients with advanced extranodal NK/T lymphoma: results of a multicenter study.

Priorities for Improving Outcomes for Nonmalignant Blood Diseases: A Report from the Blood and Marrow Transplant Clinical Trials Network.

Introduction to a review series on banked allogeneic immune effector cells.

Introduction to a How I Treat series on emergent CAR T-cell toxicities.