Detalles de la búsqueda
1.
In vitro to in vivo extrapolation to derive a metabolism factor for estimating the aggregate exposure to salicylic acid after dermal exposure of its esters.
Arch Toxicol;
98(7): 2199-2211, 2024 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-38658404
2.
Proposals for new transfer coefficient (TC) values for worker re-entry activities in grape vineyards.
Regul Toxicol Pharmacol;
150: 105628, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38621523
3.
Proposals for new spray drift exposure values in orchards and vineyards for residents and bystanders.
Regul Toxicol Pharmacol;
150: 105643, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38723936
4.
Ambient air concentrations of plant protection products: Data collection for the combined air concentration database and associated risk assessment.
Regul Toxicol Pharmacol;
149: 105627, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38621522
5.
Safety assessment for nail cosmetics: Framework for the estimation of systemic exposure through the nail plate.
Regul Toxicol Pharmacol;
148: 105588, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38423269
6.
Suitability of different reconstructed human skin models in the skin and liver Chip2 microphysiological model to investigate the kinetics and first-pass skin metabolism of the hair dye, 4-amino-2-hydroxytoluene.
J Appl Toxicol;
44(3): 333-343, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-37699698
7.
Application of a skin and liver Chip2 microphysiological model to investigate the route-dependent toxicokinetics and toxicodynamics of consumer-relevant doses of genistein.
J Appl Toxicol;
44(2): 287-300, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-37700462
8.
Practical application of the interim internal threshold of toxicological concern (iTTC): a case study based on clinical data.
Arch Toxicol;
97(1): 155-164, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36149470
9.
Workshop report: Challenges faced in developing inhalation thresholds of Toxicological Concern (TTC) - State of the science and next steps.
Regul Toxicol Pharmacol;
142: 105434, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37302561
10.
Measured air concentrations of pesticides for the estimation of exposure to vapour in European risk assessments.
Regul Toxicol Pharmacol;
136: 105285, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36372264
11.
Use of in vitro metabolism and biokinetics assays to refine predicted in vivo and in vitro internal exposure to the cosmetic ingredient, phenoxyethanol, for use in risk assessment.
Regul Toxicol Pharmacol;
131: 105132, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35217105
12.
A 10-step framework for use of read-across (RAX) in next generation risk assessment (NGRA) for cosmetics safety assessment.
Regul Toxicol Pharmacol;
129: 105094, 2022 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-34990780
13.
Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.
Regul Toxicol Pharmacol;
132: 105161, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35508214
14.
Validation of the 3D reconstructed human skin micronucleus (RSMN) assay: an animal-free alternative for following-up positive results from standard in vitro genotoxicity assays.
Mutagenesis;
36(1): 1-17, 2021 04 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-33544138
15.
Validation of the 3D reconstructed human skin Comet assay, an animal-free alternative for following-up positive results from standard in vitro genotoxicity assays.
Mutagenesis;
36(1): 19-35, 2021 04 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32152633
16.
New framework for a non-animal approach adequately assures the safety of cosmetic ingredients - A case study on caffeine.
Regul Toxicol Pharmacol;
123: 104931, 2021 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-33905778
17.
Demonstration of the first-pass metabolism in the skin of the hair dye, 4-amino-2-hydroxytoluene, using the Chip2 skin-liver microphysiological model.
J Appl Toxicol;
41(10): 1553-1567, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33594739
18.
A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals.
Regul Toxicol Pharmacol;
118: 104789, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33035627
19.
Use of human liver and EpiSkin™ S9 subcellular fractions as a screening assays to compare the in vitro hepatic and dermal metabolism of 47 cosmetics-relevant chemicals.
J Appl Toxicol;
40(3): 416-433, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31912921
20.
Comparison of the metabolism of 10 cosmetics-relevant chemicals in EpiSkin™ S9 subcellular fractions and in vitro human skin explants.
J Appl Toxicol;
40(2): 313-326, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31701564