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1.
Long-term evaluation of E6011, an anti-fractalkine monoclonal antibody, in patients with rheumatoid arthritis inadequately responding to biological disease-modifying antirheumatic drugs.
Mod Rheumatol;
34(1): 45-49, 2023 Dec 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36680420
2.
Long-term safety and efficacy of E6011, an anti-fractalkine monoclonal antibody, in patients with rheumatoid arthritis inadequately responding to methotrexate.
Mod Rheumatol;
34(1): 37-44, 2023 Dec 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36680426
3.
Phase II study of tazemetostat for relapsed or refractory B-cell non-Hodgkin lymphoma with EZH2 mutation in Japan.
Cancer Sci;
112(9): 3627-3635, 2021 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-34159682
4.
Phase 1 study on the safety and efficacy of E6011, antifractalkine antibody, in patients with Crohn's disease.
J Gastroenterol Hepatol;
36(8): 2180-2186, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-33599356
5.
A phase 2 study of E6011, an anti-Fractalkine monoclonal antibody, in patients with rheumatoid arthritis inadequately responding to biological disease-modifying antirheumatic drugs.
Mod Rheumatol;
31(4): 783-789, 2021 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-33427546
6.
Safety, pharmacokinetics, and efficacy of E6011, an antifractalkine monoclonal antibody, in a first-in-patient phase 1/2 study on rheumatoid arthritis.
Mod Rheumatol;
28(1): 58-65, 2018 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-28681650
7.
First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E6742, a Dual Antagonist of Toll-like Receptors 7 and 8, in Healthy Volunteers.
Clin Pharmacol Drug Dev;
12(4): 363-375, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36219471
8.
Dose-response relationships of rabeprazole 5, 10, 20, and 40 mg once daily on suppression of gastric acid secretion through the night in healthy Japanese individuals with different CYP2C19 genotypes.
Eur J Clin Pharmacol;
68(5): 579-88, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22108775
9.
Efficacy and Safety of E6011, an Anti-Fractalkine Monoclonal Antibody, in Patients With Active Rheumatoid Arthritis With Inadequate Response to Methotrexate: Results of a Randomized, Double-Blind, Placebo-Controlled Phase II Study.
Arthritis Rheumatol;
73(4): 587-595, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33038062
10.
Pharmacokinetic disposition of topical phosphodiesterase-4 inhibitor E6005 in patients with atopic dermatitis.
J Dermatolog Treat;
30(5): 466-470, 2019 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-30265585
11.
Efficacy and safety of twice-daily rabeprazole maintenance therapy for patients with reflux esophagitis refractory to standard once-daily proton pump inhibitor: the Japan-based EXTEND study.
J Gastroenterol;
53(7): 834-844, 2018 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-29188387
12.
Dose Finding of Lenvatinib in Subjects With Advanced Hepatocellular Carcinoma Based on Population Pharmacokinetic and Exposure-Response Analyses.
J Clin Pharmacol;
57(9): 1138-1147, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28561918
13.
Safety, tolerability and pharmacokinetics of a novel phosphodiesterase inhibitor, E6005 ointment, in healthy volunteers and in patients with atopic dermatitis.
J Dermatolog Treat;
27(3): 241-6, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26581111
14.
Efficacy of a novel phosphodiesterase inhibitor, E6005, in patients with atopic dermatitis: An investigator-blinded, vehicle-controlled study.
J Dermatolog Treat;
27(5): 467-72, 2016 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-27080209
15.
Effect of topical phosphodiesterase 4 inhibitor E6005 on Japanese children with atopic dermatitis: Results from a randomized, vehicle-controlled exploratory trial.
J Dermatol;
43(8): 881-7, 2016 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26703371
16.
Safety and efficacy of topical E6005, a phosphodiesterase 4 inhibitor, in Japanese adult patients with atopic dermatitis: results of a randomized, vehicle-controlled, multicenter clinical trial.
J Dermatol;
41(7): 577-85, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24942594
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