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1.
Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17ß-HSD10 with Implications to Alzheimer's Disease Treatment.
Int J Mol Sci;
21(6)2020 Mar 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-32192199
2.
Novel Benzothiazole-based Ureas as 17ß-HSD10 Inhibitors, A Potential Alzheimer's Disease Treatment.
Molecules;
24(15)2019 Jul 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-31362457
3.
1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders.
J Enzyme Inhib Med Chem;
33(1): 665-670, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29536773
4.
Reduction of Folate by Dihydrofolate Reductase from Thermotoga maritima.
Biochemistry;
56(13): 1879-1886, 2017 04 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28319664
5.
Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment.
Bioorg Med Chem;
25(3): 1143-1152, 2017 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28082069
6.
Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17ß-HSD10 modulators for Alzheimer's disease treatment.
Bioorg Med Chem Lett;
26(15): 3675-8, 2016 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27287370
7.
Development of submicromolar 17ß-HSD10 inhibitors and their in vitro and in vivo evaluation.
Eur J Med Chem;
258: 115593, 2023 Oct 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37390508
8.
Effects of novel 17ß-hydroxysteroid dehydrogenase type 10 inhibitors on mitochondrial respiration.
Toxicol Lett;
339: 12-19, 2021 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33359020
9.
Rational design of novel TLR4 ligands by in silico screening and their functional and structural characterization in vitro.
Eur J Med Chem;
146: 38-46, 2018 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-29407964
10.
6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17ß-HSD10 and potential drugs for Alzheimer's disease treatment: Design, synthesis and in vitro evaluation.
Med Chem;
2017 Jan 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28067167
11.
Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.
ChemMedChem;
11(12): 1264-9, 2016 06 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-26427608
12.
Benzothiazoles - scaffold of interest for CNS targeted drugs.
Curr Med Chem;
22(6): 730-47, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25515509
13.
A Direct Interaction Between Mitochondrial Proteins and Amyloid-ß Peptide and its Significance for the Progression and Treatment of Alzheimer's Disease
Curr Med Chem;
22(9): 1056 - 1085, 2015 02 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-25620098
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