Detalles de la búsqueda
1.
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
Nature;
571(7763): 72-78, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31217586
2.
Discovery of heterocyclic replacements for the coumarin core of anti-tubercular FadD32 inhibitors.
Bioorg Med Chem Lett;
28(22): 3529-3533, 2018 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30316633
3.
Determination of low levels of 2H-labeling using high-resolution mass spectrometry: application in studies of lipid flux and beyond.
Rapid Commun Mass Spectrom;
28(3): 239-44, 2014 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24375874
4.
Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice.
J Lipid Res;
54(10): 2615-22, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23828778
5.
Measurement of apo(a) kinetics in human subjects using a microfluidic device with tandem mass spectrometry.
Rapid Commun Mass Spectrom;
27(12): 1294-302, 2013 Jun 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-23681806
6.
Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver.
Cell Metab;
6(1): 69-78, 2007 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-17618857
7.
Quantifying apoprotein synthesis in rodents: coupling LC-MS/MS analyses with the administration of labeled water.
J Lipid Res;
53(6): 1223-31, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22389331
8.
Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia.
J Lipid Res;
53(1): 51-65, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22021650
9.
Measuring H(2)(18)O tracer incorporation on a QQQ-MS platform provides a rapid, transferable screening tool for relative protein synthesis.
J Proteome Res;
11(3): 1591-7, 2012 Mar 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-22289114
10.
Demonstration of diet-induced decoupling of fatty acid and cholesterol synthesis by combining gene expression array and 2H2O quantification.
Am J Physiol Endocrinol Metab;
302(2): E209-17, 2012 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22045313
11.
Measurement of fractional synthetic rates of multiple protein analytes by triple quadrupole mass spectrometry.
Clin Chem;
58(3): 619-27, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22249652
12.
A rapid method for cross-species quantitation of apolipoproteins A1, B48 and B100 in plasma by ultra-performance liquid chromatography/tandem mass spectrometry.
Rapid Commun Mass Spectrom;
26(2): 101-8, 2012 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-22173797
13.
In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS.
J Lipid Res;
52(1): 159-69, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20884843
14.
Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters.
J Lipid Res;
52(11): 1965-73, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-21841206
15.
Quantifying cholesterol synthesis in vivo using (2)H(2)O: enabling back-to-back studies in the same subject.
J Lipid Res;
52(7): 1420-8, 2011 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-21498887
16.
siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids.
J Lipid Res;
52(6): 1084-1097, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21398511
17.
The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species.
J Lipid Res;
52(6): 1150-1161, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21415123
18.
Identifying static and kinetic lipid phenotypes by high resolution UPLC-MS: unraveling diet-induced changes in lipid homeostasis by coupling metabolomics and fluxomics.
J Proteome Res;
10(9): 4281-90, 2011 Sep 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-21744776
19.
Attenuation of Slc27a5 gene expression followed by LC-MS measurement of bile acid reconjugation using metabolomics and a stable isotope tracer strategy.
J Proteome Res;
10(10): 4683-91, 2011 Oct 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-21819150
20.
An ultraperformance liquid chromatography method for the normal-phase separation of lipids.
Anal Biochem;
414(2): 266-72, 2011 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21402047