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1.

Antiplatelet properties of Pim kinase inhibition are mediated through disruption of thromboxane A2 receptor signaling.

Unsworth, Amanda J; Bye, Alexander P; Sage, Tanya; Gaspar, Renato S; Eaton, Nathan; Drew, Caleb; Stainer, Alexander; Kriek, Neline; Volberding, Peter J; Hutchinson, James L; Riley, Ryan; Jones, Sarah; Mundell, Stuart J; Cui, Weiguo; Falet, Hervé; Gibbins, Jonathan M.

Haematologica; 106(7): 1968-1978, 2021 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-32467143

2.

Opposing Roles of GSK3α and GSK3ß Phosphorylation in Platelet Function and Thrombosis.

Moore, Samantha F; Agbani, Ejaife O; Wersäll, Andreas; Poole, Alastair W; Williams, Chris M; Zhao, Xiaojuan; Li, Yong; Hutchinson, James L; Hunter, Roger W; Hers, Ingeborg.

Int J Mol Sci; 22(19)2021 Sep 30.

Artículo en Inglés | MEDLINE | ID: mdl-34638997

3.

Arrestin-3 differentially regulates platelet GPCR subsets.

Hutchinson, James L; Zhao, Xiaojuan; Hill, Rob; Mundell, Stuart J.

Platelets; 31(5): 641-645, 2020 Jul 03.

Artículo en Inglés | MEDLINE | ID: mdl-31684789

4.

Lipopolysaccharide promotes contraction of uterine myocytes via activation of Rho/ROCK signaling pathways.

Hutchinson, James L; Rajagopal, Shalini P; Yuan, Mei; Norman, Jane E.

FASEB J; 28(1): 94-105, 2014 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-24076962

5.

Ticagrelor inverse agonist activity at the P2Y₁₂ receptor is non-reversible versus its endogenous agonist adenosine 5´-diphosphate.

Khalil, Jawad; Dimofte, Tudor; Roberts, Timothy; Keith, Michael; Amaradasa, Kumuthu; Hindle, Matthew S; Bancroft, Sukhinder; Hutchinson, James L; Naseem, Khalid; Johnson, Thomas; Mundell, Stuart J.

Br J Pharmacol; 181(1): 21-35, 2024 01.

Artículo en Inglés | MEDLINE | ID: mdl-37530222

6.

Difluorinated thromboxane A₂ reveals crosstalk between platelet activatory and inhibitory pathways by targeting both the TP and IP receptors.

Allen, Megan F; Hutchinson, James L; Keith, Michael; Mallah, Shahida; Corey, Robin A; Trory, Justin S; Jing, Changcheng; Fang, Huaquan; Wei, Liang; Bennett, Steven H; Aggarwal, Varinder K; Mundell, Stuart J; Hers, Ingeborg.

Br J Pharmacol; 2024 Jun 05.

Artículo en Inglés | MEDLINE | ID: mdl-38840293

7.

Salmonella regulates polyubiquitination and surface expression of MHC class II antigens.

Lapaque, Nicolas; Hutchinson, James L; Jones, Des C; Méresse, Stéphane; Holden, David W; Trowsdale, John; Kelly, Adrian P.

Proc Natl Acad Sci U S A; 106(33): 14052-7, 2009 Aug 18.

Artículo en Inglés | MEDLINE | ID: mdl-19666567

8.

Molecular regulators of resolution of inflammation: potential therapeutic targets in the reproductive system.

Hutchinson, James L; Rajagopal, Shalini P; Sales, Kurt J; Jabbour, Henry N.

Reproduction; 142(1): 15-28, 2011 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-21490125

9.

Sphingosine-1-phosphate modulates PAR1-mediated human platelet activation in a concentration-dependent biphasic manner.

Liu, Haonan; Jackson, Molly L; Goudswaard, Lucy J; Moore, Samantha F; Hutchinson, James L; Hers, Ingeborg.

Sci Rep; 11(1): 15308, 2021 07 28.

Artículo en Inglés | MEDLINE | ID: mdl-34321503

10.

Tetherin/BST2, a physiologically and therapeutically relevant regulator of platelet receptor signalling.

Zhao, Xiaojuan; Alibhai, Dominic; Sun, Ting; Khalil, Jawad; Hutchinson, James L; Olzak, Kaya; Williams, Christopher M; Li, Yong; Sessions, Richard; Cross, Stephen; Seager, Richard; Aungraheeta, Riyaad; Leard, Alan; McKinnon, Caroline M; Phillips, David; Zhang, Lei; Poole, Alastair W; Banting, George; Mundell, Stuart J.

Blood Adv; 5(7): 1884-1898, 2021 04 13.

Artículo en Inglés | MEDLINE | ID: mdl-33792632

11.

Pharmacodynamic Comparison of Ticagrelor Monotherapy Versus Ticagrelor and Aspirin in Patients After Percutaneous Coronary Intervention: The TEMPLATE (Ticagrelor Monotherapy and Platelet Reactivity) Randomized Controlled Trial.

Johnson, Thomas W; Baos, Sarah; Collett, Laura; Hutchinson, James L; Nkau, Martin; Molina, Maria; Aungraheeta, Riyaad; Reilly-Stitt, Christopher; Bowles, Ruth; Reeves, Barnaby C; Rogers, Chris A; Mundell, Stuart J; Baumbach, Andreas; Mumford, Andrew D.

J Am Heart Assoc; 9(24): e016495, 2020 12 15.

Artículo en Inglés | MEDLINE | ID: mdl-33305660

12.

In-depth PtdIns(3,4,5)P₃ signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function.

Durrant, Tom N; Hutchinson, James L; Heesom, Kate J; Anderson, Karen E; Stephens, Len R; Hawkins, Phillip T; Marshall, Aaron J; Moore, Samantha F; Hers, Ingeborg.

Blood Adv; 1(14): 918-932, 2017 Jun 13.

Artículo en Inglés | MEDLINE | ID: mdl-29242851

13.

Transcription Analysis of the Myometrium of Labouring and Non-Labouring Women.

Sharp, Gemma C; Hutchinson, James L; Hibbert, Nanette; Freeman, Tom C; Saunders, Philippa T K; Norman, Jane E.

PLoS One; 11(5): e0155413, 2016.

Artículo en Inglés | MEDLINE | ID: mdl-27176052

14.

Anti-inflammatory mediators as physiological and pharmacological regulators of parturition.

Rinaldi, Sara F; Hutchinson, James L; Rossi, Adriano G; Norman, Jane E.

Expert Rev Clin Immunol; 7(5): 675-96, 2011 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-21895479

15.

Spinal stenosis.

Hutchinson, James L.

J Natl Med Assoc; 96(3): 384, 2004 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-15040524

16.

The laxative.

Hutchinson, James L.

J Natl Med Assoc; 95(5): 399-400, 2003 May.

Artículo en Inglés | MEDLINE | ID: mdl-12793797

17.

A Salmonella typhimurium effector protein SifA is modified by host cell prenylation and S-acylation machinery.

Reinicke, Anna T; Hutchinson, James L; Magee, Anthony I; Mastroeni, Piero; Trowsdale, John; Kelly, Adrian P.

J Biol Chem; 280(15): 14620-7, 2005 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-15710609

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