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1.

Kv1.3 blockade by ShK186 modulates CD4+ effector memory T-cell activity of patients with granulomatosis with polyangiitis.

Lintermans, Lucas L; Stegeman, Coen A; Muñoz-Elías, Ernesto J; Tarcha, Eric J; Iadonato, Shawn P; Rutgers, Abraham; Heeringa, Peter; Abdulahad, Wayel H.

Rheumatology (Oxford); 63(1): 198-208, 2024 Jan 04.

Artículo en Inglés | MEDLINE | ID: mdl-37086441

2.

A potent Lassa virus antiviral targets an arenavirus virulence determinant.

Madu, Ikenna G; Files, Megan; Gharaibeh, Dima N; Moore, Amy L; Jung, Kie-Hoon; Gowen, Brian B; Dai, Dongcheng; Jones, Kevin F; Tyavanagimatt, Shanthakumar R; Burgeson, James R; Korth, Marcus J; Bedard, Kristin M; Iadonato, Shawn P; Amberg, Sean M.

PLoS Pathog; 14(12): e1007439, 2018 12.

Artículo en Inglés | MEDLINE | ID: mdl-30576397

3.

Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain.

Romero, Haylie K; Christensen, Sean B; Di Cesare Mannelli, Lorenzo; Gajewiak, Joanna; Ramachandra, Renuka; Elmslie, Keith S; Vetter, Douglas E; Ghelardini, Carla; Iadonato, Shawn P; Mercado, Jose L; Olivera, Baldomera M; McIntosh, J Michael.

Proc Natl Acad Sci U S A; 114(10): E1825-E1832, 2017 03 07.

Artículo en Inglés | MEDLINE | ID: mdl-28223528

4.

Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway.

Pattabhi, Sowmya; Wilkins, Courtney R; Dong, Ran; Knoll, Megan L; Posakony, Jeffrey; Kaiser, Shari; Mire, Chad E; Wang, Myra L; Ireton, Renee C; Geisbert, Thomas W; Bedard, Kristin M; Iadonato, Shawn P; Loo, Yueh-Ming; Gale, Michael.

J Virol; 90(5): 2372-87, 2015 Dec 16.

Artículo en Inglés | MEDLINE | ID: mdl-26676770

5.

Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases.

Chhabra, Sandeep; Chang, Shih Chieh; Nguyen, Hai M; Huq, Redwan; Tanner, Mark R; Londono, Luz M; Estrada, Rosendo; Dhawan, Vikas; Chauhan, Satendra; Upadhyay, Sanjeev K; Gindin, Mariel; Hotez, Peter J; Valenzuela, Jesus G; Mohanty, Biswaranjan; Swarbrick, James D; Wulff, Heike; Iadonato, Shawn P; Gutman, George A; Beeton, Christine; Pennington, Michael W; Norton, Raymond S; Chandy, K George.

FASEB J; 28(9): 3952-64, 2014 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-24891519

6.

Isoflavone agonists of IRF-3 dependent signaling have antiviral activity against RNA viruses.

Bedard, Kristin M; Wang, Myra L; Proll, Sean C; Loo, Yueh-Ming; Katze, Michael G; Gale, Michael; Iadonato, Shawn P.

J Virol; 86(13): 7334-44, 2012 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-22532686

7.

Durable pharmacological responses from the peptide ShK-186, a specific Kv1.3 channel inhibitor that suppresses T cell mediators of autoimmune disease.

Tarcha, Eric J; Chi, Victor; Muñoz-Elías, Ernesto J; Bailey, David; Londono, Luz M; Upadhyay, Sanjeev K; Norton, Kayla; Banks, Amy; Tjong, Indra; Nguyen, Hai; Hu, Xueyou; Ruppert, Greg W; Boley, Scott E; Slauter, Richard; Sams, James; Knapp, Brian; Kentala, Dustin; Hansen, Zachary; Pennington, Michael W; Beeton, Christine; Chandy, K George; Iadonato, Shawn P.

J Pharmacol Exp Ther; 342(3): 642-53, 2012 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-22637724

8.

Extracellular 2'-5' oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity.

Kristiansen, Helle; Scherer, Christina A; McVean, Maralee; Iadonato, Shawn P; Vends, Susanne; Thavachelvam, Karthiga; Steffensen, Thomas B; Horan, Kristy A; Kuri, Thomas; Weber, Friedemann; Paludan, Søren R; Hartmann, Rune.

J Virol; 84(22): 11898-904, 2010 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-20844035

9.

Genomics: Hepatitis C virus gets personal.

Iadonato, Shawn P; Katze, Michael G.

Nature; 461(7262): 357-8, 2009 Sep 17.

Artículo en Inglés | MEDLINE | ID: mdl-19759611

10.

High-density rhesus macaque oligonucleotide microarray design using early-stage rhesus genome sequence information and human genome annotations.

Wallace, James C; Korth, Marcus J; Paeper, Bryan; Proll, Sean C; Thomas, Matthew J; Magness, Charles L; Iadonato, Shawn P; Nelson, Charles; Katze, Michael G.

BMC Genomics; 8: 28, 2007 Jan 23.

Artículo en Inglés | MEDLINE | ID: mdl-17244361

11.

Kv1.3 Channel Blockade Modulates the Effector Function of B Cells in Granulomatosis with Polyangiitis.

Land, Judith; Lintermans, Lucas L; Stegeman, Coen A; Muñoz-Elías, Ernesto J; Tarcha, Eric J; Iadonato, Shawn P; Heeringa, Peter; Rutgers, Abraham; Abdulahad, Wayel H.

Front Immunol; 8: 1205, 2017.

Artículo en Inglés | MEDLINE | ID: mdl-29018452

12.

Safety and pharmacodynamics of dalazatide, a Kv1.3 channel inhibitor, in the treatment of plaque psoriasis: A randomized phase 1b trial.

Tarcha, Eric J; Olsen, Chelsea M; Probst, Peter; Peckham, David; Muñoz-Elías, Ernesto J; Kruger, James G; Iadonato, Shawn P.

PLoS One; 12(7): e0180762, 2017.

Artículo en Inglés | MEDLINE | ID: mdl-28723914

13.

A small-molecule IRF3 agonist functions as an influenza vaccine adjuvant by modulating the antiviral immune response.

Probst, Peter; Grigg, John B; Wang, Myra; Muñoz, Ernesto; Loo, Yueh-Ming; Ireton, Renee C; Gale, Michael; Iadonato, Shawn P; Bedard, Kristin M.

Vaccine; 35(15): 1964-1971, 2017 04 04.

Artículo en Inglés | MEDLINE | ID: mdl-28279563

14.

Association of the FTO gene with BMI.

Hunt, Steven C; Stone, Steven; Xin, Yuanpei; Scherer, Christina A; Magness, Charles L; Iadonato, Shawn P; Hopkins, Paul N; Adams, Ted D.

Obesity (Silver Spring); 16(4): 902-4, 2008 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-18239580

15.

Distinct gene expression profiles in peripheral blood mononuclear cells from patients infected with vaccinia virus, yellow fever 17D virus, or upper respiratory infections.

Scherer, Christina A; Magness, Charles L; Steiger, Kathryn V; Poitinger, Nicholas D; Caputo, Christine M; Miner, Douglas G; Winokur, Patricia L; Klinzman, Donna; McKee, Janice; Pilar, Christine; Ward, Patricia A; Gillham, Martha H; Haulman, N Jean; Stapleton, Jack T; Iadonato, Shawn P.

Vaccine; 25(35): 6458-73, 2007 Aug 29.

Artículo en Inglés | MEDLINE | ID: mdl-17651872

16.

Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human.

Magness, Charles L; Fellin, P Campion; Thomas, Matthew J; Korth, Marcus J; Agy, Michael B; Proll, Sean C; Fitzgibbon, Matthew; Scherer, Christina A; Miner, Douglas G; Katze, Michael G; Iadonato, Shawn P.

Genome Biol; 6(7): R60, 2005.

Artículo en Inglés | MEDLINE | ID: mdl-15998449

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