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1.
BMC Health Serv Res ; 15: 538, 2015 Dec 04.
Artículo en Inglés | MEDLINE | ID: mdl-26637190

RESUMEN

BACKGROUND: The level of patient safety and outcomes accomplished depends on the quality of care provided. Previous studies found that nurse-to-patient ratio, practice environment, and nursing education were significant predictors of patient outcomes. However, the outcomes measured in previous studies were mainly inpatient mortality and failure-to-rescue rates. Few nurse-sensitive patient outcomes have been measured that quantify nurses' contribution to patient care. Selecting appropriate outcomes that reflect the clinically relevant effect of nursing care is important. Moreover previous studies were largely cross-sectional and retrospective. These research designs are limited in their ability to explain the casual links between the variables examined. This study is aimed at determining the associations among staffing levels, skill mix of baccalaureate-prepared registered nurses, and practice environment on nurse-sensitive outcomes for medical and surgical patients in public hospitals in Hong Kong. METHOD/DESIGNS: A multi-method research design will be adopted. The sample includes all medical and surgical wards of four major public hospitals that offer 24-h accident and emergency services. Multiple responses from registered nurses who work in the study wards will be collected over 12 months to examine their individual characteristics and perceptions of the practice environment. A 12-month prospective observational study will be performed to determine the association between nurse staffing levels, the practice environment, and nurse-sensitive patient outcomes including pressure ulcers, falls and restraint prevalence, urinary catheter-associated urinary tract infections, and central line catheter-associated bloodstream infections. Multilevel Cox proportional hazards models will be employed to examine the association between these patient outcomes and the explanatory nursing factors of primary interest (nurse staffing levels, education composition, and practice environment), with adjustment for all patient-, ward- and hospital-level potential confounders (age, sex, diagnosis, comorbidities, level of surgical invasiveness, mortality, length of stay, and type of admission). DISCUSSION: It is anticipated that knowledge of the association between nurse staffing levels, the practice environment, and nurse-sensitive outcomes will inform the provision of quality and timely patient care. This study will provide a landmark report that is of relevance and importance to patients and to hospital stakeholders and managers, health policy makers, nurses, and educators who advocate patient benefits. TRIAL REGISTRATION: Clinical Trials Registry CCTCTR CUHK_CCT00460 . Date of trial registration: 02 July 2015.


Asunto(s)
Personal de Enfermería en Hospital/provisión & distribución , Evaluación de Resultado en la Atención de Salud , Admisión y Programación de Personal , Adulto , Anciano , Estudios Transversales , Femenino , Hong Kong , Hospitales Públicos , Humanos , Masculino , Persona de Mediana Edad , Relaciones Enfermero-Paciente , Seguridad del Paciente , Úlcera por Presión , Estudios Retrospectivos
2.
Hong Kong Med J ; 21(5): 407-10, 2015 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-26139690

RESUMEN

OBJECTIVES: To compare the outcomes of locking plate fixation versus casting for displaced distal radius fracture with unstable fracture pattern in active Chinese elderly people. DESIGN: Historical cohort study. SETTING: Orthopaedic ward and clinic at Tseung Kwan O Hospital, Hong Kong. PATIENTS: Between 1 May 2010 and 31 October 2013, 57 Chinese elderly people aged 61 to 80 years were treated either operatively with locking plate fixation (n=26) or conservatively with cast immobilisation (n=31) for unstable displaced distal radius fracture. MAIN OUTCOME MEASURES: Clinical, radiological, and functional outcomes were assessed at 9 to 12 months after treatment. RESULTS: The functional outcome (based on the quick Disabilities of the Arm, Shoulder and Hand score) was significantly better in the locking plate fixation group than in the cast immobilisation group, while clinical and radiological outcomes were comparable with those in other similar studies. CONCLUSIONS: Locking plate fixation resulted in better functional outcome for displaced distal radius fracture with unstable fracture pattern in active Chinese elderly people aged 61 to 80 years. Further prospective study with long-term follow-up is recommended.


Asunto(s)
Moldes Quirúrgicos , Fijación Interna de Fracturas , Fracturas del Radio/cirugía , Anciano , Anciano de 80 o más Años , Placas Óseas , Femenino , Estudios de Seguimiento , Fijación Interna de Fracturas/instrumentación , Curación de Fractura , Fuerza de la Mano , Humanos , Masculino , Persona de Mediana Edad , Radiografía , Fracturas del Radio/diagnóstico por imagen , Fracturas del Radio/fisiopatología , Rango del Movimiento Articular , Resultado del Tratamiento , Articulación de la Muñeca/fisiopatología
3.
Support Care Cancer ; 21(11): 3079-84, 2013 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-23828396

RESUMEN

PURPOSE: This study aims to develop the Chinese version of the Sexual Function after Gynecologic Illness Scale (SFAGIS) and to establish its psychometric properties in Hong Kong Chinese patients with gynecological cancer. METHODS: A Chinese version of SFAGIS was developed using the Brislin model of translation and guidelines for cross-cultural adaptation of scales. The content validity and semantic equivalence were assessed by an expert panel. The translated version of SFAGIS was administered to 150 Hong Kong Chinese women with gynecological cancer to test the scale's psychometric properties and to assess its feasibility. The convergent validity of the Chinese scale was tested by correlating it with the Chinese version of the sex relations subscale of the Psychosocial Adjustment to Illness Scale Self-Report (PAIS-SR). RESULTS: The average completion time for the Chinese SFAGIS was 16.2 ± 6.6 min. The internal consistency of the Chinese SFAGIS was 0.93. Test-retest reliability was also high with an interclass correlation coefficient 0.76. A Pearson product-moment correlation found strong correlations among the Chinese SFAGIS and the Chinese version of the sex relations subscale of the PAIS-SR, indicating that both scales measure the same as or has a similar construct. CONCLUSIONS: The Chinese version of SFAGIS is a reliable and valid instrument which can be used in clinical practice and research for assessing sexual function problems in Chinese patients with gynecological cancer and to identify those in need of attention.


Asunto(s)
Adaptación Psicológica , Pueblo Asiatico/psicología , Neoplasias de los Genitales Femeninos/psicología , Psicometría/métodos , Psicometría/normas , Conducta Sexual/psicología , Adulto , Estudios de Factibilidad , Femenino , Neoplasias de los Genitales Femeninos/cirugía , Neoplasias de los Genitales Femeninos/terapia , Hong Kong , Humanos , Persona de Mediana Edad , Neoplasias Ováricas/psicología , Neoplasias Ováricas/cirugía , Neoplasias Ováricas/terapia , Reproducibilidad de los Resultados , Traducción , Neoplasias del Cuello Uterino/psicología , Neoplasias del Cuello Uterino/cirugía , Neoplasias del Cuello Uterino/terapia , Neoplasias de la Vulva/psicología , Neoplasias de la Vulva/cirugía , Neoplasias de la Vulva/terapia
4.
Hong Kong Med J ; 18(2): 131-6, 2012 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-22477736

RESUMEN

OBJECTIVES: To study the epidemiology of occupational hand injuries and associated social and industrial factors. DESIGN. For this retrospective case series of patients with occupational hand injuries, case records were retrieved to gather data. In addition, all the subjects were interviewed by a single interviewer using a predesigned questionnaire. SETTING: Division of Hand Surgery, Department of Orthopaedics and Traumatology, Queen Mary Hospital, Hong Kong. PATIENTS: A total of 250 patients with occupational hand injuries were treated during the period from 1999 to 2001. This period was chosen to obtain 10 years of follow-up data to assess return to work and any secondary injuries. MAIN OUTCOME MEASURES: Personal particulars (gender, age, marital status, education level, length of stay in Hong Kong, type of employment, wage system, personal habits, family size, number of breadwinners, income), type of industry and mode of injury, causes of injury according to the worker, work conditions, type of injury, and treatment given. RESULTS: Two groups of workers in our study had more occupational hand injuries, namely those with less than 1 year of experience on a new job and immigrants from China. Factors associated with a large proportion of occupational hand injuries were male gender with personal risk factors (smoking and regular consumption of alcohol, long working hours), and in the case of machine operators, inadequate training and use of safety devices. CONCLUSION: Occupational hand injuries lead to loss of working hours and compensation. For prevention, the workplace should be made into a safer and work-friendly environment. Workers should also have sufficient training.


Asunto(s)
Accidentes de Trabajo/estadística & datos numéricos , Traumatismos de la Mano/epidemiología , Accidentes de Trabajo/prevención & control , Adolescente , Adulto , Anciano , Niño , Femenino , Traumatismos de la Mano/etiología , Traumatismos de la Mano/prevención & control , Hong Kong/epidemiología , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Factores de Riesgo , Encuestas y Cuestionarios , Factores de Tiempo
5.
Hong Kong Med J ; 17(4): 297-300, 2011 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-21813898

RESUMEN

OBJECTIVES: For diagnosing neuropathic pain, a simple 6-item patient-completed identification pain questionnaire has been validated among Caucasians. We aimed to study the validity and reliability of this questionnaire among Hong Kong Chinese patients. DESIGN: Questionnaire survey. SETTING: Two pain clinics and two neurology clinics in Hong Kong. PATIENTS: Patients with either neuropathic pain or nociceptive pain were recruited randomly from the four clinics. The patients completed the questionnaire themselves and the diagnosis of neuropathic pain and nociceptive pain was made by the pain specialists. We determined the optimal cutoff, positive and negative predictive values, sensitivity, specificity, the area under the receiver operating characteristic curve, and test-retest reliability of the translated version. RESULTS: Among the 92 participants, 60 (65%) had neuropathic pain and 32 (35%) had nociceptive pain. At an optimal cutoff score of 3 or higher, the positive predictive value was 87% while the negative predictive value was 55%, and it correctly classified 71% of cases. The specificity and sensitivity were 81% and 65%, respectively. The area under the curve was 0.78 (P<0.001). Test-retest reliability in the 10 randomly selected patients showed a good intraclass correlation of 0.72. CONCLUSION: The Chinese Identification Pain Questionnaire is a valid and reliable scale that may be used as an initial diagnostic tool for neuropathic pain among Hong Kong Chinese patients.


Asunto(s)
Neuralgia/diagnóstico , Encuestas y Cuestionarios , Adolescente , Adulto , Anciano , Femenino , Hong Kong , Humanos , Masculino , Persona de Mediana Edad
6.
Hong Kong Med J ; 15(1): 44-52, 2009 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-19197096

RESUMEN

OBJECTIVE: To review currently available evidence on the epidemiology and methods of management for necrotising fasciitis, with particular reference to Hong Kong. DATA SOURCES AND STUDY SELECTION: Medline, PubMed, and Cochrane Library searches of local and internationally published English language journals, from 1990 to July 2008 using the terms 'necrotising fasciitis', 'Hong Kong', 'diagnosis', 'epidemiology', 'vibrio', 'streptococci', 'clostridia', and 'management'. DATA EXTRACTION: All articles involving necrotising fasciitis in Hong Kong were included in the review. DATA SYNTHESIS: The incidence of necrotising fasciitis in Hong Kong and around the world has been increasing. This rapidly progressive infection is a major cause of concern, due to its high morbidity and mortality. Up to 93% of affected patients at our hospital were admitted to the Intensive Care Unit and many still died from septic complications, such as pneumonia and multi-organ failure. Radical debridements in the form of amputations and disarticulations were considered vital in 46% of the patients. Early recognition and treatment remain the most important factors influencing survival. Yet, early diagnosis of the condition is difficult due to its similarities with many other soft tissue disorders such as cellulitis. Repeated surgical debridement or incisional drainage continues to be essential for the survival of sufferers from necrotising fasciitis. Many authorities have reported that carrying out the first fasciotomy and radical debridement within 24 hours of symptom onset was associated with significantly improved survival, which also emphasises the importance of early diagnosis. CONCLUSION: Clinicians must adopt a high index of suspicion for necrotising fasciitis. Empirical antibiotics must be started early and repeated physical examinations should be performed, while maintaining a low threshold for tissue biopsy and surgery. The timing of the first fasciotomy and radical debridement within a window of 24 hours from symptom onset is associated with significantly improved survival.


Asunto(s)
Fascitis Necrotizante , Infecciones por Bacterias Gramnegativas , Infecciones Estreptocócicas , Streptococcus pyogenes , Aeromonas/patogenicidad , Antibacterianos/uso terapéutico , Infecciones por Clostridium/complicaciones , Infecciones por Clostridium/epidemiología , Infecciones por Clostridium/microbiología , Infecciones por Clostridium/terapia , Comorbilidad , Desbridamiento , Diagnóstico Precoz , Fascitis Necrotizante/complicaciones , Fascitis Necrotizante/epidemiología , Fascitis Necrotizante/microbiología , Fascitis Necrotizante/terapia , Infecciones por Bacterias Gramnegativas/complicaciones , Infecciones por Bacterias Gramnegativas/epidemiología , Infecciones por Bacterias Gramnegativas/microbiología , Infecciones por Bacterias Gramnegativas/terapia , Bacilos Gramnegativos Anaerobios Facultativos/patogenicidad , Hong Kong/epidemiología , Humanos , Oxigenoterapia Hiperbárica , Factores de Riesgo , Infecciones Estreptocócicas/complicaciones , Infecciones Estreptocócicas/epidemiología , Infecciones Estreptocócicas/microbiología , Infecciones Estreptocócicas/terapia , Vibriosis/complicaciones , Vibriosis/epidemiología , Vibriosis/microbiología , Vibriosis/terapia
8.
Hong Kong Med J ; 14(4): 296-302, 2008 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-18685163

RESUMEN

OBJECTIVE: To review currently available evidence on the epidemiology and management of occupational repetitive strain injuries with particular reference to Hong Kong. DATA SOURCES AND STUDY SELECTION: Medline, PubMed and Cochrane Library searches of local and internationally published English journals from 1990 to 2007 regarding repetitive strain injuries. DATA EXTRACTION: All articles involving occupational repetitive strain injuries in Hong Kong were included in this review. DATA SYNTHESIS: There were 16 articles contributing data on the impact of repetitive strain injuries both in Hong Kong and around the world. There were seven articles dealing with the problem of computer station set-ups and methods for improving the workstation environments. CONCLUSION: Currently there were significant data on the impact of repetitive strain injuries in Hong Kong. The data took the form of compensation claims, days away from work, and cost of medical consultations. Other articles described proper workplace adjustments to help prevent repetitive strain injuries. However, there were no figures in the current literature showing the impact of these adjustments in reducing the incidence of repetitive strain injuries. More research could help to delineate the relationship between different types of interventions and occupational repetitive strain injuries.


Asunto(s)
Trastornos de Traumas Acumulados/diagnóstico , Trastornos de Traumas Acumulados/epidemiología , Enfermedades Musculoesqueléticas/epidemiología , Enfermedades Profesionales/epidemiología , Trastornos de Traumas Acumulados/etiología , Femenino , Hong Kong/epidemiología , Humanos , Incidencia , Puntaje de Gravedad del Traumatismo , Masculino , Enfermedades Musculoesqueléticas/diagnóstico , Enfermedades Profesionales/diagnóstico , Enfermedades Profesionales/etiología , Salud Laboral , Índice de Severidad de la Enfermedad , Lugar de Trabajo
9.
Hong Kong Med J ; 14(4): 286-91, 2008 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-18685161

RESUMEN

OBJECTIVE: To examine the relation between perceived overprotection and the psychological states of cerebral palsy patients and their primary caretakers in Hong Kong. DESIGN: Cross-sectional survey, in which data of 14 pairs of cerebral palsy patients and their caretakers were analysed. SETTING: Duchess of Kent Children's Hospital, Hong Kong. PARTICIPANTS: Cerebral palsy patients and their primary caretakers in Hong Kong. MAIN OUTCOME MEASURES: Perceived overprotection and psychological states. RESULTS: Nearly two thirds of the 14 patients (mean age of 15 years) and 86% of the 14 primary caretakers (mean age of 47 years) perceived various levels of overprotection. For both patients and caretakers, perceived overprotection was positively associated with anxiety and unhappiness. The patients' and caretakers' psychological states and perception of overprotection were not related to the actual motor ability of the patients. Perceived overprotection of the patients was not related to that of the caretakers. CONCLUSION: Caretakers should be mindful that a well-meaning move may have undesirable consequences. More support and child-rearing education should be considered for caretakers.


Asunto(s)
Cuidadores/psicología , Parálisis Cerebral/psicología , Personas con Discapacidad/psicología , Relaciones Interpersonales , Calidad de Vida , Actividades Cotidianas , Adaptación Fisiológica , Adaptación Psicológica , Adolescente , Adulto , Ansiedad/epidemiología , Ansiedad/psicología , Parálisis Cerebral/diagnóstico , Parálisis Cerebral/rehabilitación , Distribución de Chi-Cuadrado , Estudios Transversales , Trastorno Depresivo/epidemiología , Trastorno Depresivo/psicología , Evaluación de la Discapacidad , Femenino , Hong Kong , Humanos , Masculino , Persona de Mediana Edad , Probabilidad , Perfil de Impacto de Enfermedad , Apoyo Social , Encuestas y Cuestionarios , Adulto Joven
10.
J Orthop Surg (Hong Kong) ; 15(1): 27-31, 2007 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-17429113

RESUMEN

PURPOSES: To assess the tensile strength of the modified 4-strand cruciate technique for obliquely lacerated tendons, and to compare the findings with the strength of transversely lacerated tendons repaired at various grasping depths. METHODS: 60 porcine front foot tendons were evenly divided into 4 groups. In groups 1 to 3, tendons were transversely lacerated and repaired with grasping points at both ends away from the laceration by 5 mm, 10 mm, and 15 mm respectively. In group 4, tendons were obliquely lacerated and repaired with a grasping point 5 mm away from the laceration on one end and 15 mm on the other. All tendons were repaired with a modified 4-strand core suture and continuous epitendinous suture, and then tested to failure in a tensile machine. RESULTS: The tensile strength in group 1 was significantly lower than that in the other 3 groups (p<0.005). The tensile strength in group 4 was not significantly different from groups 2 and 3. CONCLUSION: The tensile strength of modified 4-strand cruciate repair configuration is not weakened in obliquely lacerated tendons; the grasping point at one end of the tendon being 15 mm away from laceration provides sufficient strength to compensate for the relatively weak 5-mm end. So long as one grasping point is away from the laceration site by 10 mm, the ultimate tensile strength of the transversely lacerated tendons appears acceptable. The modified 4-strand cruciate repair is safe to use for repairing obliquely lacerated tendons.


Asunto(s)
Traumatismos de los Pies/cirugía , Laceraciones/cirugía , Técnicas de Sutura , Animales , Traumatismos de los Pies/fisiopatología , Laceraciones/fisiopatología , Porcinos , Resistencia a la Tracción
11.
J Orthop Surg (Hong Kong) ; 15(2): 211-5, 2007 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-17709864

RESUMEN

PURPOSE: To assess a protected mobilisation programme (dynamic treatment) for proximal phalangeal fracture of the hand, irrespective of the geometry. METHODS: Clinical and radiological results of 32 consecutive patients with proximal phalangeal fracture of the hand treated from January 2001 to February 2007 were evaluated. Our supervised rehabilitation programme was strictly followed to gain full range of movement of the proximal interphalangeal joint and to prevent the development of an extension lag contracture. Patients were followed up for a mean period of 15 (range, 13-16) months. Results were evaluated using the Belsky classification. RESULTS: The results were excellent in 72% of the patients, good in 22%, and poor in 6%. Some patients defaulted follow-up, which made long-term assessment difficult. The poor results may have been related to patient non-compliance or default from rehabilitation. Many good results upgraded to excellent following further rehabilitation. CONCLUSION: Skeletal stability, not rigidity, is necessary for functional movements of the hand. Proximal phalangeal fractures can be effectively treated by closed methods, using the stabilising effect of soft tissues (zancolli complex-metacarpophalangeal retention apparatus) and external devices (metacarpophalangeal block splint), thus enabling bone healing and movement recovery at the same time.


Asunto(s)
Traumatismos de los Dedos/fisiopatología , Falanges de los Dedos de la Mano/lesiones , Fijación de Fractura/métodos , Fracturas Óseas/terapia , Adolescente , Adulto , Anciano , Niño , Femenino , Traumatismos de los Dedos/diagnóstico por imagen , Articulaciones de los Dedos/diagnóstico por imagen , Articulaciones de los Dedos/fisiopatología , Falanges de los Dedos de la Mano/diagnóstico por imagen , Estudios de Seguimiento , Fracturas Óseas/diagnóstico por imagen , Humanos , Masculino , Persona de Mediana Edad , Radiografía , Rango del Movimiento Articular , Estudios Retrospectivos , Factores de Tiempo , Resultado del Tratamiento
12.
Arch Orthop Trauma Surg ; 126(2): 131-3, 2006 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-16402197

RESUMEN

A young man presented with acute dislocation of the left elbow at the radio-capitellar articulation caused by trapping of the biceps tendon at the stalk of a solitary osteochondroma. There was no deformity of the ulna and radius shaft suggestive of a developmental growth disturbance of the forearm bones. Good reduction could be achieved by simple relocation of the biceps tendon. The osteochondroma was excised.


Asunto(s)
Neoplasias Óseas/complicaciones , Articulación del Codo , Luxaciones Articulares/etiología , Osteocondroma/complicaciones , Enfermedad Aguda , Adulto , Neoplasias Óseas/diagnóstico por imagen , Neoplasias Óseas/cirugía , Estudios de Seguimiento , Humanos , Luxaciones Articulares/diagnóstico por imagen , Luxaciones Articulares/cirugía , Masculino , Procedimientos Ortopédicos/métodos , Osteocondroma/diagnóstico por imagen , Osteocondroma/cirugía , Radiografía , Radio (Anatomía) , Rango del Movimiento Articular/fisiología , Recuperación de la Función , Medición de Riesgo , Resultado del Tratamiento
13.
Biomed Res Int ; 2016: 3459431, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27446947

RESUMEN

Autogenic fat graft usually suffers from degeneration and volume shrinkage in volume reconstruction applications. How to maintain graft viability and graft volume is an essential consideration in reconstruction therapies. In this presented investigation, a new fat graft transplantation method was developed aiming to improve long term graft viability and volume reconstruction effect by incorporation of hydrogel. The harvested fat graft is dissociated into small fragments and incorporated into a collagen based hydrogel to form a hydrogel/fat graft complex for volume reconstruction purpose. In vitro results indicate that the collagen based hydrogel can significantly improve the survivability of cells inside isolated graft. In a 6-month investigation on artificial created defect model, this hydrogel/fat graft complex filler has demonstrated the ability of promoting fat pad formation inside the targeted defect area. The newly generated fat pad can cover the whole defect and restore its original dimension in 6-month time point. Compared to simple fat transplantation, this hydrogel/fat graft complex system provides much improvement on long term volume restoration effect against degeneration and volume shrinkage. One notable effect is that there is continuous proliferation of adipose tissue throughout the 6-month period. In summary, the hydrogel/fat graft system presented in this investigation demonstrated a better and more significant effect on volume reconstruction in large sized volume defect than simple fat transplantation.


Asunto(s)
Tejido Adiposo/metabolismo , Tejido Adiposo/trasplante , Colágeno/química , Hidrogeles/química , Músculos/fisiopatología , Procedimientos de Cirugía Plástica , Células 3T3-L1 , Animales , Materiales Biocompatibles , Cicatriz , Femenino , Supervivencia de Injerto , Etiquetado Corte-Fin in Situ , Ratones , Músculos/lesiones , Pentobarbital/química , Ratas , Ratas Sprague-Dawley , Ingeniería de Tejidos , Trasplante Autólogo
14.
Hand Surg ; 10(2-3): 159-68, 2005.
Artículo en Inglés | MEDLINE | ID: mdl-16568509

RESUMEN

This article describes the development of a proximal interphalangeal (PIP) joint prosthesis based on the principles of replicating anatomical surface components, the use of macrolocking intramedullary stem and the use of a cobalt-chrome alloy material. The design features are intended to obtain an optimal range of motion while retaining stability and longevity. The final prototype, for which a patent has been filed, is described.


Asunto(s)
Articulaciones de los Dedos/cirugía , Prótesis e Implantes , Aleaciones de Cromo , Humanos , Ensayo de Materiales
15.
Aliment Pharmacol Ther ; 17(6): 799-805, 2003 Mar 15.
Artículo en Inglés | MEDLINE | ID: mdl-12641502

RESUMEN

BACKGROUND: There is controversy as to whether Helicobacter pylori and non-steroidal anti-inflammatory drugs interact to cause peptic ulcers. AIM: To study whether the eradication of H. pylori in patients on long-term non-steroidal anti-inflammatory drug therapy prevents the development of ulcers. METHODS: Patients infected with H. pylori whilst receiving long-term non-steroidal anti-inflammatory drug therapy, but with no ulcers at baseline endoscopy, were randomized to receive either triple antibiotic therapy (metronidazole 300 mg, clarithromycin 250 mg and amoxicillin 500 mg, given four times daily; n = 70) or placebo (n = 70) for 2 weeks. Non-steroidal anti-inflammatory drugs were continued throughout the study period. Endoscopy was repeated 12 weeks after the end of treatment. The development of ulcers was compared between the two groups. RESULTS: Endoscopy at 12 weeks revealed peptic ulcer development in five [7%; 95% confidence interval (CI), 2-16] of the patients who received triple therapy and in six (9%; 95% CI, 3-18) of those who received placebo (P = 1.00). No significant difference in the development of ulcers was found between patients with persistent H. pylori infection (7/80; 9%; 95% CI, 4-17) and those with the eradication of H. pylori (4/52; 8%; 95% CI, 2-19) (P = 1.00). CONCLUSIONS: The eradication of H. pylori in patients receiving long-term treatment with non-steroidal anti-inflammatory drugs did not prevent ulcer development. However, because the rate of ulcer development was low, a study with a larger sample size is required to confirm this finding.


Asunto(s)
Úlcera Duodenal/prevención & control , Infecciones por Helicobacter/tratamiento farmacológico , Helicobacter pylori , Úlcera Gástrica/prevención & control , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Amoxicilina/uso terapéutico , Antiinflamatorios no Esteroideos/uso terapéutico , Claritromicina/uso terapéutico , Método Doble Ciego , Quimioterapia Combinada/uso terapéutico , Dispepsia/etiología , Endoscopía Gastrointestinal , Femenino , Estudios de Seguimiento , Humanos , Masculino , Metronidazol/uso terapéutico , Persona de Mediana Edad
16.
J Bone Joint Surg Am ; 79(9): 1303-12, 1997 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-9314392

RESUMEN

Thirty-four displaced intra-articular fractures of the distal aspect of the radius in thirty-four patients were treated with open reduction and internal fixation with plates and screws. Although there was a high rate of complications (nine [26 per cent] of thirty-four fractures), twenty-eight patients (82 per cent) had a good or excellent result according to the system of Gartland and Werley and twenty patients (59 per cent) had a good or excellent result according to the modified system of Green and O'Brien at the most recent evaluation. Immediately postoperatively, the articular surface of the distal aspect of the radius was restored to a mean of 2 degrees of volar tilt and 20 degrees of radial angulation and radial length was improved by a mean of ten millimeters compared with the preoperative length. The articular surface was restored to congruity or to at most one millimeter of step-off in twenty-six patients (76 per cent). By the time of the most recent evaluation, the initial postoperative alignment had changed markedly in three patients (9 per cent) and degenerative osteoarthrosis (grade II or III) had developed in six patients (18 per cent). We considered that the initial postoperative alignment had changed markedly when the articular surface was displaced by two millimeters or more, when the extra-articular alignment had changed by more than 10 degrees of radial tilt, or when there was more than five millimeters of radial shortening. The potential for restoration of normal alignment and the stability of the fixation are the main advantages of internal fixation with plates. Restoration of congruity to the joint was the major difficulty in this group of patients.


Asunto(s)
Placas Óseas , Fijación Interna de Fracturas , Fracturas del Radio/cirugía , Traumatismos de la Muñeca/cirugía , Adolescente , Adulto , Femenino , Estudios de Seguimiento , Fijación Interna de Fracturas/efectos adversos , Humanos , Masculino , Persona de Mediana Edad , Radiografía , Fracturas del Radio/diagnóstico por imagen , Traumatismos de la Muñeca/diagnóstico por imagen
17.
J Orthop Trauma ; 15(5): 350-7, 2001.
Artículo en Inglés | MEDLINE | ID: mdl-11433140

RESUMEN

OBJECTIVE: To determine the ability of open reduction and plate fixation to restore articular congruity in the treatment of fractures of the distal radius with intraarticular comminution and displacement. DESIGN: Prospectively followed series. METHODS: Eighteen consecutive fractures of the distal radius with intraarticular comminution and displacement were treated with open reduction and combined volar and dorsal plate fixation in thirteen, dorsal plate fixation in four, and volar plate fixation in one case. Kirschner wires were added in thirteen fractures and cancellous bone graft was used in four fractures. Articular congruity after a mean follow-up of twenty-three months was assessed using anteroposterior and lateral radiographs. RESULTS: Articular congruity without a two millimeter or more intraarticular stepoff was found at follow-up in fifteen of eighteen cases, without a two millimeter or more gap in nine cases and without a two millimeter or more stepoff or gap in only eight cases. One reason for not having obtained articular congruity in some of the fractures was insufficient intraoperative visualization of the joint surface. Three reduced fractures redisplaced. The reason for loss of intraarticular reduction was considered insufficient stabilization of the distal fragments. In two of the three cases, it was thought that insertion of bone graft would have prevented the loss of reduction. CONCLUSIONS: Articular incongruity after open reduction and plate fixation of comminuted fractures of the distal radius may occur more often than expected. The reduced fracture should be evaluated by intraoperative radiographs. If the reduced joint surface is not entirely visible on the radiographs because of implants or other reasons, oblique radiographs or fluoroscopy should be additionally used. Plate fixation alone does not always provide sufficient stability and cancellous bone graft should be added in cases of metaphyseal bone loss or for stabilization of multiple small articular fragments that cannot be fixed by screws or Kirschner wires.


Asunto(s)
Placas Óseas , Fijación de Fractura/métodos , Fracturas Conminutas/cirugía , Complicaciones Posoperatorias/terapia , Fracturas del Radio/cirugía , Adulto , Anciano , Femenino , Estudios de Seguimiento , Humanos , Inmovilización , Masculino , Persona de Mediana Edad , Terapia Ocupacional , Modalidades de Fisioterapia , Complicaciones Posoperatorias/diagnóstico por imagen , Estudios Prospectivos , Radiografía
18.
Med Biol Eng Comput ; 41(6): 710-7, 2003 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-14686597

RESUMEN

Recent commercially available miniature sensors have the potential to improve the functions of functional electrical stimulation (FES) systems in terms of control, reliability and robustness. A new control approach using a miniature gyroscope and an accelerometer was studied. These sensors were used to detect the linear acceleration and angular velocity of residual voluntary movements on upper limbs and were small and easy to put on. Five healthy subjects and three cervical spinal cord injured subjects were recruited to evaluate this controller. Sensors were placed on four locations: the shoulder, upper arm, wrist and hand. A quick forward-and-backward movement was employed to produce a distinctive waveform that was different from general movements. A detection algorithm was developed to generate a command signal by identifying this distinctive waveform through the detection of peaks and valleys in the sensor's signals. This command signal was used to control different FES hand grasp patterns. With a specificity of 0.9, the sensors had a success rate of 85-100% on healthy subjects and 82-97% on spinal cord injured subjects. In terms of sensor placement, the gyroscope was better as a control source than the accelerometer for wrist and hand positions, but the reverse was true for the shoulder.


Asunto(s)
Terapia por Estimulación Eléctrica/métodos , Fuerza de la Mano , Paraplejía/rehabilitación , Traumatismos de la Médula Espinal/rehabilitación , Adulto , Algoritmos , Vértebras Cervicales , Humanos , Movimiento (Física)
19.
J Hand Surg Br ; 22(2): 283-7, 1997 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-9150009

RESUMEN

We report a prospective study of dynamic splintage following extensor tendon repair. Eighty-four patients with 101 extensor tendon injuries were studied. Using Dargan's evaluation system, there were 97% excellent results for the thumb and 93% excellent and good results for the fingers. The average total active motions were 107 degrees for thumbs and 245 degrees for fingers. Over 80% of patients regained good power grip. Patients with associated digital fractures or with ragged lacerations had poorer results. Overall, we found that dynamic splintage was a satisfactory method after extensor repair.


Asunto(s)
Traumatismos de los Dedos/cirugía , Férulas (Fijadores) , Traumatismos de los Tendones/cirugía , Pulgar/lesiones , Traumatismos de los Dedos/rehabilitación , Fracturas Óseas/rehabilitación , Fracturas Óseas/cirugía , Fuerza de la Mano , Humanos , Estudios Prospectivos , Traumatismos de los Tendones/rehabilitación , Resultado del Tratamiento
20.
J Hand Surg Br ; 21(6): 760-4, 1996 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-8982919

RESUMEN

The mechanical rigidity obtained by external fixation in a comminuted phalangeal fracture model was assessed and the results compared with two other types of internal fixation commonly used (lateral plate and crossed Kirschner wires) in a biomechanical cadaver study. Each fixation technique was tested in apex palmar bending, compression and torsion. The results showed that lateral plating provided the best rigidity in apex palmar bending and compression and that external fixation and Kirschner wires showed the same mechanical properties. For the torque test, external fixation provided the best rigidity.


Asunto(s)
Fijadores Externos , Traumatismos de los Dedos/cirugía , Fracturas Conminutas/cirugía , Fenómenos Biomecánicos , Placas Óseas , Hilos Ortopédicos , Diseño de Equipo , Traumatismos de los Dedos/fisiopatología , Fracturas Conminutas/fisiopatología , Humanos , Resistencia a la Tracción
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