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1.

An 80,000-Piece Puzzle of Alzheimer's Disease.

Iram, Tal; Keller, Andreas; Wyss-Coray, Tony.

Immunity; 50(6): 1349-1351, 2019 06 18.

Artículo en Inglés | MEDLINE | ID: mdl-31216459

2.

Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17.

Iram, Tal; Kern, Fabian; Kaur, Achint; Myneni, Saket; Morningstar, Allison R; Shin, Heather; Garcia, Miguel A; Yerra, Lakshmi; Palovics, Robert; Yang, Andrew C; Hahn, Oliver; Lu, Nannan; Shuken, Steven R; Haney, Michael S; Lehallier, Benoit; Iyer, Manasi; Luo, Jian; Zetterberg, Henrik; Keller, Andreas; Zuchero, J Bradley; Wyss-Coray, Tony.

Nature; 605(7910): 509-515, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-35545674

3.

SRF transcriptionally regulates the oligodendrocyte cytoskeleton during CNS myelination.

Iram, Tal; Garcia, Miguel A; Amand, Jérémy; Kaur, Achint; Atkins, Micaiah; Iyer, Manasi; Lam, Mable; Ambiel, Nicholas; Jorgens, Danielle M; Keller, Andreas; Wyss-Coray, Tony; Kern, Fabian; Zuchero, J Bradley.

Proc Natl Acad Sci U S A; 121(12): e2307250121, 2024 Mar 19.

Artículo en Inglés | MEDLINE | ID: mdl-38483990

4.

Physiological blood-brain transport is impaired with age by a shift in transcytosis.

Yang, Andrew C; Stevens, Marc Y; Chen, Michelle B; Lee, Davis P; Stähli, Daniel; Gate, David; Contrepois, Kévin; Chen, Winnie; Iram, Tal; Zhang, Lichao; Vest, Ryan T; Chaney, Aisling; Lehallier, Benoit; Olsson, Niclas; du Bois, Haley; Hsieh, Ryan; Cropper, Haley C; Berdnik, Daniela; Li, Lulin; Wang, Elizabeth Y; Traber, Gavin M; Bertozzi, Carolyn R; Luo, Jian; Snyder, Michael P; Elias, Joshua E; Quake, Stephen R; James, Michelle L; Wyss-Coray, Tony.

Nature; 583(7816): 425-430, 2020 07.

Artículo en Inglés | MEDLINE | ID: mdl-32612231

5.

The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity.

Ramirez-Ortiz, Zaida G; Pendergraft, William F; Prasad, Amit; Byrne, Michael H; Iram, Tal; Blanchette, Christopher J; Luster, Andrew D; Hacohen, Nir; El Khoury, Joseph; Means, Terry K.

Nat Immunol; 14(9): 917-26, 2013 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-23892722

6.

CD22 blockade restores homeostatic microglial phagocytosis in ageing brains.

Pluvinage, John V; Haney, Michael S; Smith, Benjamin A H; Sun, Jerry; Iram, Tal; Bonanno, Liana; Li, Lulin; Lee, Davis P; Morgens, David W; Yang, Andrew C; Shuken, Steven R; Gate, David; Scott, Madeleine; Khatri, Purvesh; Luo, Jian; Bertozzi, Carolyn R; Bassik, Michael C; Wyss-Coray, Tony.

Nature; 568(7751): 187-192, 2019 04.

Artículo en Inglés | MEDLINE | ID: mdl-30944478

7.

Author Correction: Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17.

Iram, Tal; Kern, Fabian; Kaur, Achint; Myneni, Saket; Morningstar, Allison R; Shin, Heather; Garcia, Miguel A; Yerra, Lakshmi; Palovics, Robert; Yang, Andrew C; Hahn, Oliver; Lu, Nannan; Shuken, Steven R; Haney, Michael S; Lehallier, Benoit; Iyer, Manasi; Luo, Jian; Zetterberg, Henrik; Keller, Andreas; Zuchero, J Bradley; Wyss-Coray, Tony.

Nature; 613(7942): E1, 2023 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-36513761

8.

Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes.

Iram, Tal; Ramirez-Ortiz, Zaida; Byrne, Michael H; Coleman, Uwanda A; Kingery, Nathan D; Means, Terry K; Frenkel, Dan; El Khoury, Joseph.

J Neurosci; 36(19): 5185-92, 2016 05 11.

Artículo en Inglés | MEDLINE | ID: mdl-27170117

9.

Nucleolin inhibitor GroA triggers reduction in epidermal growth factor receptor activation: Pharmacological implication for glial scarring after spinal cord injury.

Goldshmit, Yona; Schokoroy Trangle, Sari; Afergan, Fabian; Iram, Tal; Pinkas-Kramarski, Ronit.

J Neurochem; 138(6): 845-58, 2016 09.

Artículo en Inglés | MEDLINE | ID: mdl-27399849

10.

Astrocytes from old Alzheimer's disease mice are impaired in Aß uptake and in neuroprotection.

Iram, Tal; Trudler, Dorit; Kain, David; Kanner, Sivan; Galron, Ronit; Vassar, Robert; Barzilai, Ari; Blinder, Pablo; Fishelson, Zvi; Frenkel, Dan.

Neurobiol Dis; 96: 84-94, 2016 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-27544484

11.

A protocol for collection and infusion of cerebrospinal fluid in mice.

Kaur, Achint; Shuken, Steven; Yang, Andrew Chris; Iram, Tal.

STAR Protoc; 4(1): 102015, 2023 03 17.

Artículo en Inglés | MEDLINE | ID: mdl-36638015

12.

Limited Proteolysis-Mass Spectrometry Reveals Aging-Associated Changes in Cerebrospinal Fluid Protein Abundances and Structures.

Shuken, Steven R; Rutledge, Jarod; Iram, Tal; Losada, Patricia Moran; Wilson, Edward N; Andreasson, Katrin I; Leib, Ryan D; Wyss-Coray, Tony.

Nat Aging; 2(5): 379-388, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-36741774

13.

The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C.

Pluvinage, John V; Sun, Jerry; Claes, Christel; Flynn, Ryan A; Haney, Michael S; Iram, Tal; Meng, Xiangling; Lindemann, Rachel; Riley, Nicholas M; Danhash, Emma; Chadarevian, Jean Paul; Tapp, Emma; Gate, David; Kondapavulur, Sravani; Cobos, Inma; Chetty, Sundari; PaÈca, Anca M; PaÈca, Sergiu P; Berry-Kravis, Elizabeth; Bertozzi, Carolyn R; Blurton-Jones, Mathew; Wyss-Coray, Tony.

Sci Transl Med; 13(622): eabg2919, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34851695

14.

Single Cell ADNP Predictive of Human Muscle Disorders: Mouse Knockdown Results in Muscle Wasting.

Kapitansky, Oxana; Karmon, Gidon; Sragovich, Shlomo; Hadar, Adva; Shahoha, Meishar; Jaljuli, Iman; Bikovski, Lior; Giladi, Eliezer; Palovics, Robert; Iram, Tal; Gozes, Illana.

Cells; 9(10)2020 10 19.

Artículo en Inglés | MEDLINE | ID: mdl-33086621

15.

Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain.

Marschallinger, Julia; Iram, Tal; Zardeneta, Macy; Lee, Song E; Lehallier, Benoit; Haney, Michael S; Pluvinage, John V; Mathur, Vidhu; Hahn, Oliver; Morgens, David W; Kim, Justin; Tevini, Julia; Felder, Thomas K; Wolinski, Heimo; Bertozzi, Carolyn R; Bassik, Michael C; Aigner, Ludwig; Wyss-Coray, Tony.

Nat Neurosci; 23(10): 1308, 2020 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-32719564

16.

Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain.

Marschallinger, Julia; Iram, Tal; Zardeneta, Macy; Lee, Song E; Lehallier, Benoit; Haney, Michael S; Pluvinage, John V; Mathur, Vidhu; Hahn, Oliver; Morgens, David W; Kim, Justin; Tevini, Julia; Felder, Thomas K; Wolinski, Heimo; Bertozzi, Carolyn R; Bassik, Michael C; Aigner, Ludwig; Wyss-Coray, Tony.

Nat Neurosci; 23(2): 294, 2020 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-32005940

17.

Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain.

Marschallinger, Julia; Iram, Tal; Zardeneta, Macy; Lee, Song E; Lehallier, Benoit; Haney, Michael S; Pluvinage, John V; Mathur, Vidhu; Hahn, Oliver; Morgens, David W; Kim, Justin; Tevini, Julia; Felder, Thomas K; Wolinski, Heimo; Bertozzi, Carolyn R; Bassik, Michael C; Aigner, Ludwig; Wyss-Coray, Tony.

Nat Neurosci; 23(2): 194-208, 2020 02.

Artículo en Inglés | MEDLINE | ID: mdl-31959936

18.

Single-cell analysis of cytoskeleton dynamics: From isoelectric focusing to live cell imaging and RNA-seq.

Gozes, Illana; Ivashko-Pachima, Yanina; Kapitansky, Oxana; Sayas, Carmen Laura; Iram, Tal.

J Neurosci Methods; 323: 119-124, 2019 07 15.

Artículo en Inglés | MEDLINE | ID: mdl-31150696

19.

Publisher Correction: Limited proteolysis-mass spectrometry reveals aging-associated changes in cerebrospinal fluid protein abundances and structures.

Shuken, Steven R; Rutledge, Jarod; Iram, Tal; Losada, Patricia Moran; Wilson, Edward N; Andreasson, Katrin I; Leib, Ryan D; Wyss-Coray, Tony.

Nat Aging; 2(5): 455, 2022 May.

Artículo en Inglés | MEDLINE | ID: mdl-37118077

20.

Impaired Autophagy in APOE4 Astrocytes.

Simonovitch, Shira; Schmukler, Eran; Bespalko, Alina; Iram, Tal; Frenkel, Dan; Holtzman, David M; Masliah, Eliezer; Michaelson, Danny M; Pinkas-Kramarski, Ronit.

J Alzheimers Dis; 51(3): 915-27, 2016.

Artículo en Inglés | MEDLINE | ID: mdl-26923027

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An 80,000-Piece Puzzle of Alzheimer's Disease.

Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17.

SRF transcriptionally regulates the oligodendrocyte cytoskeleton during CNS myelination.

Physiological blood-brain transport is impaired with age by a shift in transcytosis.

The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity.

CD22 blockade restores homeostatic microglial phagocytosis in ageing brains.

Author Correction: Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17.

Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes.

Nucleolin inhibitor GroA triggers reduction in epidermal growth factor receptor activation: Pharmacological implication for glial scarring after spinal cord injury.

Astrocytes from old Alzheimer's disease mice are impaired in Aß uptake and in neuroprotection.

A protocol for collection and infusion of cerebrospinal fluid in mice.

Limited Proteolysis-Mass Spectrometry Reveals Aging-Associated Changes in Cerebrospinal Fluid Protein Abundances and Structures.

The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C.

Single Cell ADNP Predictive of Human Muscle Disorders: Mouse Knockdown Results in Muscle Wasting.

Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain.

Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain.

Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain.

Single-cell analysis of cytoskeleton dynamics: From isoelectric focusing to live cell imaging and RNA-seq.

Publisher Correction: Limited proteolysis-mass spectrometry reveals aging-associated changes in cerebrospinal fluid protein abundances and structures.

Impaired Autophagy in APOE4 Astrocytes.