1.
J Org Chem
; 82(4): 2281-2287, 2017 02 17.
Artículo
en Inglés
| MEDLINE
| ID: mdl-28102677
RESUMEN
The palladium-catalyzed alkylation reaction of 2,3,3-trifluoroallylic carbonates with indoles afforded a trifluoromethyl group possessing 3-substituted indole derivatives. The reaction proceeded via attack of the C-3 carbon of the indoles onto the C-2 position of the allylic moiety and intramolecular construction of the trifluoromethyl group by the intramolecular fluorine atom shift from the C-2 position to the C-3 position of the allyl unit.
2.
Org Biomol Chem
; 15(14): 2938-2946, 2017 Apr 05.
Artículo
en Inglés
| MEDLINE
| ID: mdl-28290580
RESUMEN
We demonstrated the ruthenium-catalyzed allylic amination of 2,3,3-trifluoroallylic carbonates with several types of amines. The reactions proceeded with several types of amines, and succeeded in obtaining polyfluorinated terminal alkenes possessing branched allylic amines as a single regioisomer.