Búsqueda | Portal de Búsqueda de la BVS España

1.

ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.

Zyryanova, Alisa F; Kashiwagi, Kazuhiro; Rato, Claudia; Harding, Heather P; Crespillo-Casado, Ana; Perera, Luke A; Sakamoto, Ayako; Nishimoto, Madoka; Yonemochi, Mayumi; Shirouzu, Mikako; Ito, Takuhiro; Ron, David.

Mol Cell; 81(1): 88-103.e6, 2021 01 07.

Artículo en Inglés | MEDLINE | ID: mdl-33220178

2.

HCV IRES Captures an Actively Translating 80S Ribosome.

Yokoyama, Takeshi; Machida, Kodai; Iwasaki, Wakana; Shigeta, Tomoaki; Nishimoto, Madoka; Takahashi, Mari; Sakamoto, Ayako; Yonemochi, Mayumi; Harada, Yoshie; Shigematsu, Hideki; Shirouzu, Mikako; Tadakuma, Hisashi; Imataka, Hiroaki; Ito, Takuhiro.

Mol Cell; 74(6): 1205-1214.e8, 2019 06 20.

Artículo en Inglés | MEDLINE | ID: mdl-31080011

3.

The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA.

Iwasaki, Shintaro; Iwasaki, Wakana; Takahashi, Mari; Sakamoto, Ayako; Watanabe, Chiduru; Shichino, Yuichi; Floor, Stephen N; Fujiwara, Koichi; Mito, Mari; Dodo, Kosuke; Sodeoka, Mikiko; Imataka, Hiroaki; Honma, Teruki; Fukuzawa, Kaori; Ito, Takuhiro; Ingolia, Nicholas T.

Mol Cell; 73(4): 738-748.e9, 2019 02 21.

Artículo en Inglés | MEDLINE | ID: mdl-30595437

4.

Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.

Tanaka, Mayuki; Yokoyama, Takeshi; Saito, Hironori; Nishimoto, Madoka; Tsuda, Kengo; Sotta, Naoyuki; Shigematsu, Hideki; Shirouzu, Mikako; Iwasaki, Shintaro; Ito, Takuhiro; Fujiwara, Toru.

Nat Chem Biol; 20(5): 605-614, 2024 May.

Artículo en Inglés | MEDLINE | ID: mdl-38267667

5.

Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers.

Hosaka, Toshiaki; Nomura, Takashi; Kubo, Minoru; Nakane, Takanori; Fangjia, Luo; Sekine, Shun-Ichi; Ito, Takuhiro; Murayama, Kazutaka; Ihara, Kentaro; Ehara, Haruhiko; Kashiwagi, Kazuhiro; Katsura, Kazushige; Akasaka, Ryogo; Hisano, Tamao; Tanaka, Tomoyuki; Tanaka, Rie; Arima, Toshi; Yamashita, Ayumi; Sugahara, Michihiro; Naitow, Hisashi; Matsuura, Yoshinori; Yoshizawa, Susumu; Tono, Kensuke; Owada, Shigeki; Nureki, Osamu; Kimura-Someya, Tomomi; Iwata, So; Nango, Eriko; Shirouzu, Mikako.

Proc Natl Acad Sci U S A; 119(9)2022 03 01.

Artículo en Inglés | MEDLINE | ID: mdl-35197289

6.

Protection of eIF2B from inhibitory phosphorylated eIF2: A viral strategy to maintain mRNA translation during the PKR-triggered integrated stress response.

Ito, Takuhiro; Wuerth, Jennifer Deborah; Weber, Friedemann.

J Biol Chem; 299(11): 105287, 2023 11.

Artículo en Inglés | MEDLINE | ID: mdl-37742919

7.

Nondomain biopolymers: Flexible molecular strategies to acquire biological functions.

Arakawa, Kazuharu; Hirose, Tetsuro; Inada, Toshifumi; Ito, Takuhiro; Kai, Toshie; Oyama, Masaaki; Tomari, Yukihide; Yoda, Takao; Nakagawa, Shinichi.

Genes Cells; 28(8): 539-552, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-37249032

8.

The landscape of translational stall sites in bacteria revealed by monosome and disome profiling.

Fujita, Tomoya; Yokoyama, Takeshi; Shirouzu, Mikako; Taguchi, Hideki; Ito, Takuhiro; Iwasaki, Shintaro.

RNA; 28(3): 290-302, 2022 03.

Artículo en Inglés | MEDLINE | ID: mdl-34906996

9.

Crystal structure of eukaryotic translation initiation factor 2B.

Kashiwagi, Kazuhiro; Takahashi, Mari; Nishimoto, Madoka; Hiyama, Takuya B; Higo, Toshiaki; Umehara, Takashi; Sakamoto, Kensaku; Ito, Takuhiro; Yokoyama, Shigeyuki.

Nature; 531(7592): 122-5, 2016 Mar 03.

Artículo en Inglés | MEDLINE | ID: mdl-26901872

10.

Incorporation of Halogenated Amino Acids into Antibody Fragments at Multiple Specific Sites Enhances Antigen Binding.

Hayashi, Akiko; Haruna, Ken-Ichi; Sato, Haruna; Ito, Kenichiro; Makino, Chisato; Ito, Takuhiro; Sakamoto, Kensaku.

Chembiochem; 22(1): 120-123, 2021 01 05.

Artículo en Inglés | MEDLINE | ID: mdl-32815262

11.

Switching on stress.

Kashiwagi, Kazuhiro; Ito, Takuhiro.

Nat Chem Biol; 20(4): 394-395, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-37945895

12.

eIF2B and the Integrated Stress Response: A Structural and Mechanistic View.

Marintchev, Assen; Ito, Takuhiro.

Biochemistry; 59(13): 1299-1308, 2020 04 07.

Artículo en Inglés | MEDLINE | ID: mdl-32200625

13.

Glial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model.

Terumitsu-Tsujita, Mika; Kitaura, Hiroki; Miura, Ikuo; Kiyama, Yuji; Goto, Fumiko; Muraki, Yoshiko; Ominato, Shiho; Hara, Norikazu; Simankova, Anna; Bizen, Norihisa; Kashiwagi, Kazuhiro; Ito, Takuhiro; Toyoshima, Yasuko; Kakita, Akiyoshi; Manabe, Toshiya; Wakana, Shigeharu; Takebayashi, Hirohide; Igarashi, Hironaka.

J Neurochem; 154(1): 25-40, 2020 07.

Artículo en Inglés | MEDLINE | ID: mdl-31587290

14.

Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.

Ito, Takuhiro; Masuda, Isao; Yoshida, Ken-ichi; Goto-Ito, Sakurako; Sekine, Shun-ichi; Suh, Se Won; Hou, Ya-Ming; Yokoyama, Shigeyuki.

Proc Natl Acad Sci U S A; 112(31): E4197-205, 2015 Aug 04.

Artículo en Inglés | MEDLINE | ID: mdl-26183229

15.

Expression, purification, and crystallization of Schizosaccharomyces pombe eIF2B.

Kashiwagi, Kazuhiro; Shigeta, Tomoaki; Imataka, Hiroaki; Ito, Takuhiro; Yokoyama, Shigeyuki.

J Struct Funct Genomics; 17(1): 33-8, 2016 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-27023709

16.

Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions.

Ito, Takuhiro; Yokoyama, Shigeyuki.

Nature; 467(7315): 612-6, 2010 Sep 30.

Artículo en Inglés | MEDLINE | ID: mdl-20882017

17.

Crystal Structure of Okadaic Acid Binding Protein 2.1: A Sponge Protein Implicated in Cytotoxin Accumulation.

Ehara, Haruhiko; Makino, Marie; Kodama, Koichiro; Konoki, Keiichi; Ito, Takuhiro; Sekine, Shun-ichi; Fukuzawa, Seketsu; Yokoyama, Shigeyuki; Tachibana, Kazuo.

Chembiochem; 16(10): 1435-9, 2015 Jul 06.

Artículo en Inglés | MEDLINE | ID: mdl-25965326

18.

Controlling the fluorescence of benzofuran-modified uracil residues in oligonucleotides by triple-helix formation.

Kanamori, Takashi; Ohzeki, Hiroki; Masaki, Yoshiaki; Ohkubo, Akihiro; Takahashi, Mari; Tsuda, Kengo; Ito, Takuhiro; Shirouzu, Mikako; Kuwasako, Kanako; Muto, Yutaka; Sekine, Mitsuo; Seio, Kohji.

Chembiochem; 16(1): 167-76, 2015 Jan 02.

Artículo en Inglés | MEDLINE | ID: mdl-25469677

19.

Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.

Hanawa-Suetsugu, Kyoko; Kukimoto-Niino, Mutsuko; Mishima-Tsumagari, Chiemi; Akasaka, Ryogo; Ohsawa, Noboru; Sekine, Shun-ichi; Ito, Takuhiro; Tochio, Naoya; Koshiba, Seizo; Kigawa, Takanori; Terada, Takaho; Shirouzu, Mikako; Nishikimi, Akihiko; Uruno, Takehito; Katakai, Tomoya; Kinashi, Tatsuo; Kohda, Daisuke; Fukui, Yoshinori; Yokoyama, Shigeyuki.

Proc Natl Acad Sci U S A; 109(9): 3305-10, 2012 Feb 28.

Artículo en Inglés | MEDLINE | ID: mdl-22331897

20.

Crystal structure of the eukaryotic translation initiation factor 2A from Schizosaccharomyces pombe.

Kashiwagi, Kazuhiro; Ito, Takuhiro; Yokoyama, Shigeyuki.

J Struct Funct Genomics; 15(3): 125-30, 2014 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-24569939

Portal de Búsqueda de la BVS España

Información y Conocimiento para la Salud

Configurar filtros

Su selección (0)

Formato de exportación:

Exportar: