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1.
Pd(II)-Catalyzed Synthesis of Alicyclic[b]-Fused Pyridines via C(sp2)-H Activation of α,ß-Unsaturated N-Acetyl Hydrazones with Vinyl Azides.
J Org Chem;
87(1): 159-171, 2022 01 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34931823
2.
Novel difluoromethyl-containing 1-((4-methoxy-3-(piperazin-1-yl)phenyl)sulfonyl)-1H-indole scaffold as potent 5-HT6R antagonists: Design, synthesis, biological evaluation, and early in vivo cognition-enhancing studies.
Bioorg Med Chem;
70: 116917, 2022 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35839536
3.
Novel difluoromethylated 1-(phenylsulfonyl)-4-(piperazin-1-yl)-1H-indole derivatives as potent 5-HT6 receptor antagonist with AMDE-improving properties: Design, synthesis, and biological evaluation.
Bioorg Med Chem;
71: 116950, 2022 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35926324
4.
Safety, Tolerability, and Pharmacokinetics of the Monoamine Oxidase B Inhibitor, HEC122505, and its Major Metabolite After Single- and Multiple- Ascending Dose, and Food Effect Study in Healthy Chinese Subjects.
Eur J Drug Metab Pharmacokinet;
49(3): 331-341, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38446388
5.
Design, synthesis and evaluation of novel monoamine oxidase B (MAO-B) inhibitors with improved pharmacokinetic properties for Parkinson's disease.
Eur J Med Chem;
252: 115308, 2023 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37001389
6.
Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter.
J Med Chem;
66(1): 371-383, 2023 01 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36598095
7.
Enhancing monoamine oxidase B inhibitory activity via chiral fluorination: Structure-activity relationship, biological evaluation, and molecular docking study.
Eur J Med Chem;
228: 114025, 2022 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34871839
8.
Synthesis and biological evaluation of novel (thio)urea derivatives as potential antitumor agents.
Arch Pharm (Weinheim);
344(11): 741-4, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-21956458
9.
Synthesis and biological evaluation of 1-(4-(piperazin-1-yl)phenyl)pyridin-2(1H)-one derivatives as potential SSRIs.
Eur J Med Chem;
223: 113644, 2021 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34182358
10.
Design, synthesis and biological evaluation of pyridinylmethylenepiperidine derivatives as potent 5-HT1F receptor agonists for migraine therapy.
Eur J Med Chem;
225: 113782, 2021 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34419891
11.
Computational Fragment-Based Design Facilitates Discovery of Potent and Selective Monoamine Oxidase-B (MAO-B) Inhibitor.
J Med Chem;
63(23): 15021-15036, 2020 12 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33210537
12.
Synthesis and antitumor activity of novel chalcone derivatives.
Biomed Pharmacother;
67(3): 215-7, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23478573
13.
Synthesis and antitumor activity of ureas containing pyrimidinyl group.
Eur J Med Chem;
46(1): 429-32, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21144621
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