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1.

The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis.

Alvarez-Diaz, Silvia; Dillon, Christopher P; Lalaoui, Najoua; Tanzer, Maria C; Rodriguez, Diego A; Lin, Ann; Lebois, Marion; Hakem, Razq; Josefsson, Emma C; O'Reilly, Lorraine A; Silke, John; Alexander, Warren S; Green, Douglas R; Strasser, Andreas.

Immunity; 45(3): 513-526, 2016 09 20.

Artículo en Inglés | MEDLINE | ID: mdl-27523270

2.

Deletion of Grin1 in mouse megakaryocytes reveals NMDA receptor role in platelet function and proplatelet formation.

Hearn, James I; Green, Taryn N; Hisey, Colin L; Bender, Markus; Josefsson, Emma C; Knowlton, Nicholas; Baumann, Juliane; Poulsen, Raewyn C; Bohlander, Stefan K; Kalev-Zylinska, Maggie L.

Blood; 139(17): 2673-2690, 2022 04 28.

Artículo en Inglés | MEDLINE | ID: mdl-35245376

3.

The RNA-binding protein SRSF3 has an essential role in megakaryocyte maturation and platelet production.

Heazlewood, Shen Y; Ahmad, Tanveer; Mohenska, Monika; Guo, Belinda B; Gangatirkar, Pradnya; Josefsson, Emma C; Ellis, Sarah L; Ratnadiwakara, Madara; Cao, Huimin; Cao, Benjamin; Heazlewood, Chad K; Williams, Brenda; Fulton, Madeline; White, Jacinta F; Ramialison, Mirana; Nilsson, Susan K; Änkö, Minna-Liisa.

Blood; 139(9): 1359-1373, 2022 03 03.

Artículo en Inglés | MEDLINE | ID: mdl-34852174

4.

Apoptotic Ablation of Platelets Reduces Atherosclerosis in Mice With Diabetes.

Lee, Man K S; Kraakman, Michael J; Dragoljevic, Dragana; Hanssen, Nordin M J; Flynn, Michelle C; Al-Sharea, Annas; Sreejit, Gopalkrishna; Bertuzzo-Veiga, Camilla; Cooney, Olivia D; Baig, Fatima; Morriss, Elizabeth; Cooper, Mark E; Josefsson, Emma C; Kile, Benjamin T; Nagareddy, Prabhakara R; Murphy, Andrew J.

Arterioscler Thromb Vasc Biol; 41(3): 1167-1178, 2021 03.

Artículo en Inglés | MEDLINE | ID: mdl-33441028

5.

The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments.

Zhang, Jian-Guo; Czabotar, Peter E; Policheni, Antonia N; Caminschi, Irina; Wan, Soo San; Kitsoulis, Susie; Tullett, Kirsteen M; Robin, Adeline Y; Brammananth, Rajini; van Delft, Mark F; Lu, Jinhua; O'Reilly, Lorraine A; Josefsson, Emma C; Kile, Benjamin T; Chin, Wei Jin; Mintern, Justine D; Olshina, Maya A; Wong, Wilson; Baum, Jake; Wright, Mark D; Huang, David C S; Mohandas, Narla; Coppel, Ross L; Colman, Peter M; Nicola, Nicos A; Shortman, Ken; Lahoud, Mireille H.

Immunity; 36(4): 646-57, 2012 Apr 20.

Artículo en Inglés | MEDLINE | ID: mdl-22483802

6.

Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion.

Pleines, Irina; Lebois, Marion; Gangatirkar, Pradnya; Au, Amanda E; Lane, Rachael M; Henley, Katya J; Kauppi, Maria; Corbin, Jason; Cannon, Ping; Bernardini, Jonathan; Alwis, Imala; Jarman, Kate E; Ellis, Sarah; Metcalf, Donald; Jackson, Shaun P; Schoenwaelder, Simone M; Kile, Benjamin T; Josefsson, Emma C.

Blood; 132(2): 197-209, 2018 07 12.

Artículo en Inglés | MEDLINE | ID: mdl-29784641

7.

Regulation of Platelet Production and Life Span: Role of Bcl-xL and Potential Implications for Human Platelet Diseases.

Josefsson, Emma C; Vainchenker, William; James, Chloe.

Int J Mol Sci; 21(20)2020 Oct 14.

Artículo en Inglés | MEDLINE | ID: mdl-33066573

8.

Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL.

Potts, Kathryn S; Sargeant, Tobias J; Dawson, Caleb A; Josefsson, Emma C; Hilton, Douglas J; Alexander, Warren S; Taoudi, Samir.

Blood; 126(6): 807-16, 2015 Aug 06.

Artículo en Inglés | MEDLINE | ID: mdl-25995324

9.

Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis.

Lee, Stanley C W; Miller, Sarah; Hyland, Craig; Kauppi, Maria; Lebois, Marion; Di Rago, Ladina; Metcalf, Donald; Kinkel, Sarah A; Josefsson, Emma C; Blewitt, Marnie E; Majewski, Ian J; Alexander, Warren S.

Blood; 126(2): 167-75, 2015 Jul 09.

Artículo en Inglés | MEDLINE | ID: mdl-26036803

10.

Regulation of platelet membrane protein shedding in health and disease.

Au, Amanda E; Josefsson, Emma C.

Platelets; 28(4): 342-353, 2017 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-27494300

11.

Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation.

Ng, Ashley P; Kauppi, Maria; Metcalf, Donald; Hyland, Craig D; Josefsson, Emma C; Lebois, Marion; Zhang, Jian-Guo; Baldwin, Tracey M; Di Rago, Ladina; Hilton, Douglas J; Alexander, Warren S.

Proc Natl Acad Sci U S A; 111(16): 5884-9, 2014 Apr 22.

Artículo en Inglés | MEDLINE | ID: mdl-24711413

12.

Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan.

Liu, Zhi-Jian; Hoffmeister, Karin M; Hu, Zhongbo; Mager, Donald E; Ait-Oudhia, Sihem; Debrincat, Marlyse A; Pleines, Irina; Josefsson, Emma C; Kile, Benjamin T; Italiano, Joseph; Ramsey, Haley; Grozovsky, Renata; Veng-Pedersen, Peter; Chavda, Chaitanya; Sola-Visner, Martha.

Blood; 123(22): 3381-9, 2014 May 29.

Artículo en Inglés | MEDLINE | ID: mdl-24599546

13.

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo.

Potts, Kathryn S; Sargeant, Tobias J; Markham, John F; Shi, Wei; Biben, Christine; Josefsson, Emma C; Whitehead, Lachlan W; Rogers, Kelly L; Liakhovitskaia, Anna; Smyth, Gordon K; Kile, Benjamin T; Medvinsky, Alexander; Alexander, Warren S; Hilton, Douglas J; Taoudi, Samir.

Blood; 124(17): 2725-9, 2014 Oct 23.

Artículo en Inglés | MEDLINE | ID: mdl-25079356

14.

Regulation of platelet lifespan by apoptosis.

Lebois, Marion; Josefsson, Emma C.

Platelets; 27(6): 497-504, 2016 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-27100842

15.

Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease.

Mason, Kylie D; Lin, Ann; Robb, Lorraine; Josefsson, Emma C; Henley, Katya J; Gray, Daniel H D; Kile, Benjamin T; Roberts, Andrew W; Strasser, Andreas; Huang, David C S; Waring, Paul; O'Reilly, Lorraine A.

Proc Natl Acad Sci U S A; 110(7): 2599-604, 2013 Feb 12.

Artículo en Inglés | MEDLINE | ID: mdl-23349374

16.

Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function.

White, Michael J; Schoenwaelder, Simone M; Josefsson, Emma C; Jarman, Kate E; Henley, Katya J; James, Chloé; Debrincat, Marlyse A; Jackson, Shaun P; Huang, David C S; Kile, Benjamin T.

Blood; 119(18): 4283-90, 2012 May 03.

Artículo en Inglés | MEDLINE | ID: mdl-22294729

17.

Mcl-1 and Bcl-x(L) coordinately regulate megakaryocyte survival.

Debrincat, Marlyse A; Josefsson, Emma C; James, Chloé; Henley, Katya J; Ellis, Sarah; Lebois, Marion; Betterman, Kelly L; Lane, Rachael M; Rogers, Kelly L; White, Michael J; Roberts, Andrew W; Harvey, Natasha L; Metcalf, Donald; Kile, Benjamin T.

Blood; 119(24): 5850-8, 2012 Jun 14.

Artículo en Inglés | MEDLINE | ID: mdl-22374700

18.

Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice.

Jansen, A J Gerard; Josefsson, Emma C; Rumjantseva, Viktoria; Liu, Qiyong Peter; Falet, Hervé; Bergmeier, Wolfgang; Cifuni, Stephen M; Sackstein, Robert; von Andrian, Ulrich H; Wagner, Denisa D; Hartwig, John H; Hoffmeister, Karin M.

Blood; 119(5): 1263-73, 2012 Feb 02.

Artículo en Inglés | MEDLINE | ID: mdl-22101895

19.

The origin and function of platelet glycosyltransferases.

Wandall, Hans H; Rumjantseva, Viktoria; Sørensen, Anne Louise Tølbøll; Patel-Hett, Sunita; Josefsson, Emma C; Bennett, Eric P; Italiano, Joseph E; Clausen, Henrik; Hartwig, John H; Hoffmeister, Karin M.

Blood; 120(3): 626-35, 2012 Jul 19.

Artículo en Inglés | MEDLINE | ID: mdl-22613794

20.

Effect of thrombopoietin receptor agonists on the apoptotic profile of platelets in patients with chronic immune thrombocytopenia.

Mitchell, William Beau; Pinheiro, Mariana P; Boulad, Nayla; Kaplan, David; Edison, Michele N; Psaila, Bethan; Karpoff, Marissa; White, Michael J; Josefsson, Emma C; Kile, Benjamin T; Bussel, James B.

Am J Hematol; 89(12): E228-34, 2014 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-25132654

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