RESUMEN
We conducted an investigation at a poultry processing plant in New Zealand to estimate the prevalence of warts among workers and the risk of developing warts associated with specific work areas or individual work practices. We obtained information on demographic characteristics and self-reported medical and occupational histories from 88 (83%) of 106 permanent employees at the plant; almost half (39 people or 44%) had developed wart-like lesions on their arms or hands after they began working at this plant. We also conducted clinical evaluations of 28 of the 32 (88%) people with wart-like lesions at the time of the investigation; in all but one case, a diagnosis of warts was confirmed. We collected scrapings of warts from 22 (79%) people and identified human papillomavirus (HPV) type 7, which is reportedly uncommon in the general public, in 12 of these specimens. People working at the time of their interview in areas where they often handled dead, raw, unfrozen chickens were three times more likely to have developed warts (Odds ratio [OR] = 3.0, 95% confidence interval [CI]: 1.2-8.0); for those who had ever worked in these 'high-risk' areas, this excess risk almost doubled (OR = 5.6, 95% CI: 2.1-14.7). Nine of the 12 (75%) people with HPV type 7 had worked in these areas at some time. In contrast to previous reports, we found no increased risk of having warts associated with environmental factors or the frequency of cuts and abrasions.(ABSTRACT TRUNCATED AT 250 WORDS)
Asunto(s)
Industria de Procesamiento de Alimentos , Enfermedades Profesionales/epidemiología , Exposición Profesional , Aves de Corral , Verrugas/epidemiología , Adolescente , Adulto , Animales , Brazo , Femenino , Dermatosis de la Mano/epidemiología , Dermatosis de la Mano/etiología , Humanos , Masculino , Persona de Mediana Edad , Nueva Zelanda/epidemiología , Enfermedades Profesionales/etiología , Prevalencia , Factores de Riesgo , Verrugas/etiologíaRESUMEN
Pseudoporphyria is a condition clinically and ultrastructurally identical to porphyria cutanea tarda but with no associated abnormality of heme synthesis. A 45-year-old woman with bullae on the dorsa of her hands was found on investigation to have pseudoporphyria. Her symptoms remitted following the cessation of naproxen therapy.
Asunto(s)
Naproxeno/efectos adversos , Porfirias/inducido químicamente , Animales , Biopsia , Diagnóstico Diferencial , Epidermólisis Ampollosa/patología , Femenino , Mano , Humanos , Microscopía Electrónica , Microscopía Fluorescente , Persona de Mediana Edad , Porfirias/patología , Porfirinas/sangre , Porfirinas/orina , Ovinos , Piel/irrigación sanguínea , Piel/patologíaAsunto(s)
Hexaclorociclohexano/uso terapéutico , Escabiosis/tratamiento farmacológico , Instituciones de Atención Ambulatoria/estadística & datos numéricos , Dermatología/estadística & datos numéricos , Resistencia a Medicamentos , Hexaclorociclohexano/administración & dosificación , Humanos , Incidencia , Nueva Zelanda/epidemiología , Derivación y Consulta/estadística & datos numéricos , Escabiosis/diagnóstico , Escabiosis/epidemiología , Factores de Tiempo , Insuficiencia del TratamientoRESUMEN
A case of pellagra is described that occurred in a patient with an eating disorder and who presented with marked photosensitivity and diarrhoea. We found urinary 5-hydroxy-indole-acetic acid to be low and suggest that this may be a useful screening test. To our knowledge this is only the second reported case of pellagra associated with an eating disorder.