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1.

NF-κB subunits direct kinetically distinct transcriptional cascades in antigen receptor-activated B cells.

Zhao, Mingming; Chauhan, Prashant; Sherman, Cheryl A; Singh, Amit; Kaileh, Mary; Mazan-Mamczarz, Krystyna; Ji, Hongkai; Joy, Jaimy; Nandi, Satabdi; De, Supriyo; Zhang, Yongqing; Fan, Jinshui; Becker, Kevin G; Loke, Png; Zhou, Weiqiang; Sen, Ranjan.

Nat Immunol; 24(9): 1552-1564, 2023 09.

Artículo en Inglés | MEDLINE | ID: mdl-37524800

2.

DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.

Roy, Roshni; Ramamoorthy, Senthilkumar; Shapiro, Benjamin D; Kaileh, Mary; Hernandez, Dena; Sarantopoulou, Dimitra; Arepalli, Sampath; Boller, Sören; Singh, Amit; Bektas, Arsun; Kim, Jaekwan; Moore, Ann Zenobia; Tanaka, Toshiko; McKelvey, Julia; Zukley, Linda; Nguyen, Cuong; Wallace, Tonya; Dunn, Christopher; Wersto, Robert; Wood, William; Piao, Yulan; Becker, Kevin G; Coletta, Christopher; De, Supriyo; Sen, Jyoti Misra; Battle, Alexis; Weng, Nan-Ping; Grosschedl, Rudolf; Ferrucci, Luigi; Sen, Ranjan.

Immunity; 54(11): 2465-2480.e5, 2021 11 09.

Artículo en Inglés | MEDLINE | ID: mdl-34706222

3.

DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.

Roy, Roshni; Ramamoorthy, Senthilkumar; Shapiro, Benjamin D; Kaileh, Mary; Hernandez, Dena; Sarantopoulou, Dimitra; Arepalli, Sampath; Boller, Sö Ren; Singh, Amit; Bektas, Arsun; Kim, Jaekwan; Moore, Ann Zenobia; Tanaka, Toshiko; McKelvey, Julia; Zukley, Linda; Nguyen, Cuong; Wallace, Tonya; Dunn, Christopher; Wersto, Robert; Wood, William; Piao, Yulan; Becker, Kevin G; Coletta, Christopher; De, Supriyo; Sen, Jyoti Misra; Battle, Alexis; Weng, Nan-Ping; Grosschedl, Rudolf; Ferrucci, Luigi; Sen, Ranjan.

Immunity; 55(6): 1135, 2022 Jun 14.

Artículo en Inglés | MEDLINE | ID: mdl-35704994

4.

Transcriptomic and Proteomic of Gastrocnemius Muscle in Peripheral Artery Disease.

Ferrucci, Luigi; Candia, Julián; Ubaida-Mohien, Ceereena; Lyashkov, Alexey; Banskota, Nirad; Leeuwenburgh, Christiaan; Wohlgemuth, Stephanie; Guralnik, Jack M; Kaileh, Mary; Zhang, Dongxue; Sufit, Robert; De, Supriyo; Gorospe, Myriam; Munk, Rachel; Peterson, Charlotte A; McDermott, Mary M.

Circ Res; 132(11): 1428-1443, 2023 05 26.

Artículo en Inglés | MEDLINE | ID: mdl-37154037

5.

Postmitotic G1 phase survivin drives mitogen-independent cell division of B lymphocytes.

Singh, Amit; Spitzer, Matthew H; Joy, Jaimy P; Kaileh, Mary; Qiu, Xiang; Nolan, Garry P; Sen, Ranjan.

Proc Natl Acad Sci U S A; 119(18): e2115567119, 2022 05 03.

Artículo en Inglés | MEDLINE | ID: mdl-35476510

6.

Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling.

Stadanlick, Jason E; Kaileh, Mary; Karnell, Fredrick G; Scholz, Jean L; Miller, Juli P; Quinn, William J; Brezski, Randall J; Treml, Laura S; Jordan, Kimberly A; Monroe, John G; Sen, Ranjan; Cancro, Michael P.

Nat Immunol; 9(12): 1379-87, 2008 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-18978795

7.

NF-κB function in B lymphocytes.

Kaileh, Mary; Sen, Ranjan.

Immunol Rev; 246(1): 254-71, 2012 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-22435560

8.

RelA-mediated signaling connects adaptation to chronic cardiomyocyte stress with myocardial and systemic inflammation in the ADCY8 model of accelerated aging.

Kumar, Vikas; Bermea, Kevin Christian; Kumar, Dhaneshwar; Singh, Amit; Verma, Anjali; Kaileh, Mary; Sen, Ranjan; Lakatta, Edward G; Adamo, Luigi.

Geroscience; 2024 Mar 19.

Artículo en Inglés | MEDLINE | ID: mdl-38499959

9.

Cross-sectional analysis of healthy individuals across decades: Aging signatures across multiple physiological compartments.

Moaddel, Ruin; Ubaida-Mohien, Ceereena; Tanaka, Toshiko; Tian, Qu; Candia, Julián; Moore, Ann Zenobia; Lovett, Jacqueline; Fantoni, Giovanna; Shehadeh, Nader; Turek, Lisa; Collingham, Victoria; Kaileh, Mary; Chia, Chee W; Sen, Ranjan; Egan, Josephine M; Ferrucci, Luigi.

Aging Cell; 23(1): e13902, 2024 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-37350292

10.

Association of Plasma Markers of Alzheimer's Disease, Neurodegeneration, and Neuroinflammation with the Choroid Plexus Integrity in Aging.

Bouhrara, Mustapha; Walker, Keenan A; R Alisch, Joseph S; Gong, Zhaoyuan; Mazucanti, Caio H; Lewis, Alexandria; Moghekar, Abhay R; Turek, Lisa; Collingham, Victoria; Shehadeh, Nader; Fantoni, Giovanna; Kaileh, Mary; Bergeron, Christopher M; Bergeron, Jan; Resnick, Susan M; Egan, Josephine M.

Aging Dis; 2024 Jan 08.

Artículo en Inglés | MEDLINE | ID: mdl-38300640

11.

Transcription factor TFII-I fine tunes innate properties of B lymphocytes.

Singh, Amit; Kaileh, Mary; De, Supriyo; Mazan-Mamczarz, Krystyna; Bayarsaihan, Dashzeveg; Sen, Ranjan; Roy, Ananda L.

Front Immunol; 14: 1067459, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-36756127

12.

Human Metabolome Reference Database in a Biracial Cohort across the Adult Lifespan.

Tian, Qu; Adam, M Gordian; Ozcariz, Enrique; Fantoni, Giovanna; Shehadeh, Nader M; Turek, Lisa M; Collingham, Victoria L; Kaileh, Mary; Moaddel, Ruin; Ferrucci, Luigi.

Metabolites; 13(5)2023 Apr 25.

Artículo en Inglés | MEDLINE | ID: mdl-37233632

13.

Whole-genome methylation analysis of aging human tissues identifies age-related changes in developmental and neurological pathways.

Tharakan, Ravi; Ubaida-Mohien, Ceereena; Dunn, Christopher; Kaileh, Mary; Tryggvadottir, Rakel; Zukley, Linda; Chia, Chee W; Sen, Ranjan; Ferrucci, Luigi.

Aging Cell; 22(7): e13847, 2023 07.

Artículo en Inglés | MEDLINE | ID: mdl-37309088

14.

Cardiomyocyte-specific adenylyl cyclase type-8 overexpression induces activation of RelA together with myocardial and systemic inflammation.

Kumar, Vikas; Bermea, Kevin Christian; Kumar, Dhaneshwar; Singh, Amit; Verma, Anjali; Kaileh, Mary; Sen, Ranjan; Lakatta, Edward G; Adamo, Luigi.

bioRxiv; 2023 Dec 04.

Artículo en Inglés | MEDLINE | ID: mdl-37790465

15.

Aging and Inflammation.

Singh, Amit; Schurman, Shepherd H; Bektas, Arsun; Kaileh, Mary; Roy, Roshni; Wilson, David M; Sen, Ranjan; Ferrucci, Luigi.

Cold Spring Harb Perspect Med; 2023 Dec 05.

Artículo en Inglés | MEDLINE | ID: mdl-38052484

16.

Epigenetic signature of human immune aging in the GESTALT study.

Roy, Roshni; Kuo, Pei-Lun; Candia, Julián; Sarantopoulou, Dimitra; Ubaida-Mohien, Ceereena; Hernandez, Dena; Kaileh, Mary; Arepalli, Sampath; Singh, Amit; Bektas, Arsun; Kim, Jaekwan; Moore, Ann Z; Tanaka, Toshiko; McKelvey, Julia; Zukley, Linda; Nguyen, Cuong; Wallace, Tonya; Dunn, Christopher; Wood, William; Piao, Yulan; Coletta, Christopher; De, Supriyo; Sen, Jyoti; Weng, Nan-Ping; Sen, Ranjan; Ferrucci, Luigi.

Elife; 122023 08 17.

Artículo en Inglés | MEDLINE | ID: mdl-37589453

17.

Transcriptomes of human primary skin fibroblasts of healthy individuals reveal age-associated mRNAs and long noncoding RNAs.

Tsitsipatis, Dimitrios; Martindale, Jennifer L; Mazan-Mamczarz, Krystyna; Herman, Allison B; Piao, Yulan; Banskota, Nirad; Yang, Jen-Hao; Cui, Linna; Anerillas, Carlos; Chang, Ming-Wen; Kaileh, Mary; Munk, Rachel; Yang, Xiaoling; Ubaida-Mohien, Ceereena; Chia, Chee W; Karikkineth, Ajoy C; Zukley, Linda; D'Agostino, Jarod; Abdelmohsen, Kotb; Basisty, Nathan; De, Supriyo; Ferrucci, Luigi; Gorospe, Myriam.

Aging Cell; 22(11): e13915, 2023 11.

Artículo en Inglés | MEDLINE | ID: mdl-37462262

18.

HiIDDD: a high-throughput imaging pipeline for the quantitative detection of DNA damage in primary human immune cells.

Gallant, Kelsey; Bektas, Arsun; Kaileh, Mary; Lustig, Ana; Ferrucci, Luigi; Pegoraro, Gianluca; Misteli, Tom.

Sci Rep; 12(1): 6335, 2022 04 15.

Artículo en Inglés | MEDLINE | ID: mdl-35428779

19.

Proteomes of primary skin fibroblasts from healthy individuals reveal altered cell responses across the life span.

Tsitsipatis, Dimitrios; Martindale, Jennifer L; Ubaida-Mohien, Ceereena; Lyashkov, Alexey; Yanai, Hagai; Kashyap, Amogh; Shin, Chang Hoon; Herman, Allison B; Ji, Eunbyul; Yang, Jen-Hao; Munk, Rachel; Dunn, Christopher; Lukyanenko, Yevgeniya; Yang, Xiaoling; Chia, Chee W; Karikkineth, Ajoy C; Zukley, Linda; D'Agostino, Jarod; Kaileh, Mary; Cui, Chang-Yi; Beerman, Isabel; Ferrucci, Luigi; Gorospe, Myriam.

Aging Cell; 21(5): e13609, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-35429111

20.

Skeletal muscle transcriptome in healthy aging.

Tumasian, Robert A; Harish, Abhinav; Kundu, Gautam; Yang, Jen-Hao; Ubaida-Mohien, Ceereena; Gonzalez-Freire, Marta; Kaileh, Mary; Zukley, Linda M; Chia, Chee W; Lyashkov, Alexey; Wood, William H; Piao, Yulan; Coletta, Christopher; Ding, Jun; Gorospe, Myriam; Sen, Ranjan; De, Supriyo; Ferrucci, Luigi.

Nat Commun; 12(1): 2014, 2021 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-33795677

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NF-κB subunits direct kinetically distinct transcriptional cascades in antigen receptor-activated B cells.

DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.

DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.

Transcriptomic and Proteomic of Gastrocnemius Muscle in Peripheral Artery Disease.

Postmitotic G1 phase survivin drives mitogen-independent cell division of B lymphocytes.

Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling.

NF-κB function in B lymphocytes.

RelA-mediated signaling connects adaptation to chronic cardiomyocyte stress with myocardial and systemic inflammation in the ADCY8 model of accelerated aging.

Cross-sectional analysis of healthy individuals across decades: Aging signatures across multiple physiological compartments.

Association of Plasma Markers of Alzheimer's Disease, Neurodegeneration, and Neuroinflammation with the Choroid Plexus Integrity in Aging.

Transcription factor TFII-I fine tunes innate properties of B lymphocytes.

Human Metabolome Reference Database in a Biracial Cohort across the Adult Lifespan.

Whole-genome methylation analysis of aging human tissues identifies age-related changes in developmental and neurological pathways.

Cardiomyocyte-specific adenylyl cyclase type-8 overexpression induces activation of RelA together with myocardial and systemic inflammation.

Aging and Inflammation.

Epigenetic signature of human immune aging in the GESTALT study.

Transcriptomes of human primary skin fibroblasts of healthy individuals reveal age-associated mRNAs and long noncoding RNAs.

HiIDDD: a high-throughput imaging pipeline for the quantitative detection of DNA damage in primary human immune cells.

Proteomes of primary skin fibroblasts from healthy individuals reveal altered cell responses across the life span.

Skeletal muscle transcriptome in healthy aging.