Anomalous photoluminescence of InAs surface quantum dots: intensity enhancement and strain control by underlying quantum dots.

Strain control and photoluminescence (PL) enhancement of InAs surface quantum dots (SQDs), exposed to ambient conditions, have been achieved by introducing underlying buried quantum dots (BQDs). The PL wavelength has been tuned from 1270 to as long as 1780 nm, redshifted as the size of the SQDs is reduced. This is in strong contrast to standard QDs, in which blueshift is observed from smaller QDs following basic quantum mechanics. Here, smaller SQDs, both in height and base area, as observed by atomic force microscopy, were obtained with wider GaAs spacer thickness between the SQDs and BQDs. The result strongly suggests that strain and related effects dominate the electronic properties of the SQDs rather than their size, and that a change in the complex strain field occurs through the spacer. The underlying BQDs also serve as effective carrier reservoirs. A PL intensity enhancement of 17 fold was observed as the GaAs spacer thickness was reduced from 150 to 10 nm. A large portion of the photoexcited carriers is initially captured and stored in the BQDs. When sufficient carriers are transferred to fill non-radiative surface states, the excess may be transferred to the SQDs enhancing the luminescence.

Flow-cytometric identification and detection of Porphyromonas gingivalis by a LPS specific monoclonal antibody.

The purpose of this study was to identify Porphyromonas gingivalis (P. gingivalis) by flow cytometry (FCM) using a monoclonal antibody (MAb) OMR-Bg1E directed to P. gingivalis-specific lipopolysaccharide (LPS). The P. gingivalis strains ATCC 33277, 381, ESO75, W50, and A7A1 were selected for the study. Fusobacterium nucleatum (F. nucleatum), Prevotella intermedia (P. intermedia), Campylobacter rectus (C. rectus), Streptococcus sanguis (S. sanguis) and Actinobacillus actinomycetemcomitans (A. actinomycetemcomitans) served as controls. A suspension of 10(7) bacteria/ml of each bacteria was prepared and then reacted with a P. gingivalis specific MAb OMR-Bg1E and fluorescein isothiocyanate (FITC) labeled second antibody. These samples were analyzed by FCM. Bacterial specific binding aggregate on data was separated out by the forward- and side-angle-scatter characteristics, while non-specific binding (NSB) was eliminated by excluding the region with mouse IgG-positive and second antibody-positive area. FCM detected a mean range of 56.2% to 97.2% P. gingivalis strains. There was a 5.1% non-specific binding using FCM to non-P. gingivalis strains. When the P. gingivalis concentration was adjusted to 10(2), 10(4), and 10(6) bacteria/ml, a detection rate of 35.7%, 48.1%, and 91.4%, was respectively observed. The lower sensitivity of the flow cytometric assay was 10(2) bacteria/ml. When P. gingivalis was added to P. intermedia suspension at 1, 20, 40, 60, and 80%, the MAb-positive fraction yielded by FCM displayed a coefficient of determination of 0.967 with the actual percentage of P. gingivalis and could be regressed to a linear function.(ABSTRACT TRUNCATED AT 250 WORDS)

[Clinical studies on te concentration of cefaclor in sera and lung tissues of patients with respiratory diseases].

A 500 mg dose of cefaclor (CCL) was administered orally before surgery to each of patients with respiratory diseases and in fasting. Average concentrations of CCL in sera were 4.04 micrograms/ml at 1.5 hours, 3.03 micrograms/ml at 2 hours, 1.68 microgram/ml at 3 hours and 0.45 microgram/ml at 5 hours after administration. Average concentrations in lung tissues during operation were 0.120 microgram/g at 3 hours, 0.272 microgram/g at 4 hours and 0.297 microgram/g at 5 hours after administration. Ratios of concentrations of CCL in lung tissues to that in sera were from 7.1 to 66.0 percent. The CCL was considered to be a useful antibiotic for the treatment of patients with respiratory diseases.

[Clinical study of cefmenoxime in thoracic surgery. Transfer of cefmenoxime to lung tissue and pleural fluid and prophylaxis of postoperative infections].

Twenty-six patients who underwent pulmonary resection for the lung disease were administered 1 g of cefmenoxime (CMX) by intravenous drip infusion just before the operation. The CMX levels in the serum, lung tissue and pleural fluid were measured using the agar-well technique. The effect of the drug on the prophylaxis of postoperative infections was investigated. The obtained results are summarized as follows; 1. The peak concentration of CMX in the serum was 58.23 micrograms/ml 1 hour after starting the drip infusion of 1 g of CMX. The serum half-life of CMX (beta-phase) was 2.15 hours. 2. The ratio of the CMX concentration in lung tissue to the peak serum level was 14.9% 202 minutes after starting the drip infusion. In the pulmonary lesion, the ratio was 9.72% at the 201 minutes. In the bronchiole, the ratio was 20.7% 191 minutes after starting the drip infusion. 3. The concentration of CMX in the pleural fluid was 2.53 micrograms/ml 12 hours after starting the drip infusion. 4. CMX is useful as a prophylaxis of postoperative infections after thoracotomy, because no postoperative infectious complications were observed.

[A case report of pulmonary actinomycosis presenting as a mass shadow on chest X-ray].

A 58-year-old man admitted to hospital because of hemoptysis. Chest X-ray showed a large mass in the right middle lobe. A tumor marker CYFRA was slightly elevated. Despite a detailed examination after admission, no definite diagnosis was made. Lung cancer was suspected and a middle lobectomy was performed. Histopathological specimen of resected lung showed typical "sulfur granule" of actinomycosis. Pulmonary actinomycosis should be included in the differential diagnosis of a pulmonary mass lesion.

[A case of panpleuropneumonectomy for diffuse pleural mesothelioma].

A 73-year-old male was admitted with dyspnea and cough. The chest X-ray showed left massive pleural effusion and diffuse pleural tumor in the left thorax. It was diagnosed as epithelial-cell type mesothelioma by pleural needle biopsy. After conforming the regression of the tumor from conducting two courses of combined treatment with cisplatin and doxorubicin, panpleuropneumonectomy was performed. He died from sepsis on the thirty second day after operation due to complication of postoperative diaphragmatic hernia and gastric perforation. When conducting a panpleuropneumonectomy to diffuse pleural mesothelioma, the most appropriate approach must be taken to the combined with resection and reconstruction of the diaphragma.

[A case with esophageal carcinoma associated with metastatic pulmonary tumor in lung cancer at seven years after the resection of lung cancer].

A 69-year-old woman was admitted to our hospital because of dysphasia. The upper G-I examination showed a stenosis at the middle thoracic esophagus and poorly differentiated adenocarcinoma was revealed histologically. Chest CT scan showed a mass shadow in the right upper lobe of the lung. She had undergone a partial resection of right upper lobe because of lung cancer seven years before. She was diagnosed as metachrous double carcinoma of the lung and the esophagus. The method of surgery included right upper lobectomy of the lung, esophagectomy and intrathoracic esophageal reconstruction using the gastric tube. The patient manifested pneumonia due to the failure of the sutures after the surgery and died on the twentieth postoperative day. When conducting simultaneous resection of both cancer and esophageal reconstruction for the double cancer of the lung and the esophagus, it was considered necessary to conduct the anastomosis outside the thoracic cavity for the purpose of preventing the pulmonary complication due to the failure of the sutures.