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1.
A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1.
Cancer Cell Int;
23(1): 36, 2023 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-36841758
2.
Discovery of EP300/CBP histone acetyltransferase inhibitors through scaffold hopping of 1,4-oxazepane ring.
Bioorg Med Chem Lett;
66: 128726, 2022 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35413416
3.
4-Pyridone-3-carboxylic acid as a benzoic acid bioisostere: Design, synthesis, and evaluation of EP300/CBP histone acetyltransferase inhibitors.
Bioorg Med Chem Lett;
51: 128358, 2021 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34534674
4.
Synthesis of Chiral cis-Cyclopropane Bearing Indole and Chromone as Potential TNFα Inhibitors.
J Org Chem;
83(15): 7672-7682, 2018 08 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30004223
5.
Tethered 1,2-Si-Group Migrations in Radical-Mediated Ring Enlargements of Cyclic Alkoxysilanes: An EPR Spectroscopic and Computational Investigation.
J Org Chem;
82(13): 6886-6894, 2017 07 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28581743
6.
Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor.
J Med Chem;
66(1): 695-715, 2023 01 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36572866
7.
Design and Synthesis of Cyclopropane Congeners of Resolvin E2, an Endogenous Proresolving Lipid Mediator, as Its Stable Equivalents.
Org Lett;
18(24): 6224-6227, 2016 12 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-27978690
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