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1.
J Invasive Cardiol ; 35(10)2023 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-37984328

RESUMEN

A 59-year-old Asian woman with paroxysmal supraventricular tachycardia (PSVT), diabetes, and dyslipidemia was hospitalized with palpitations and chest discomfort. Her electrocardiogram showed short RP tachycardia with a heart rate of 167 bpm. She received intravenous adenosine with successful restoration of sinus rhythm and resolution of her symptoms.


Asunto(s)
Taquicardia Paroxística , Taquicardia Supraventricular , Femenino , Humanos , Persona de Mediana Edad , Taquicardia Supraventricular/diagnóstico , Vasos Coronarios/diagnóstico por imagen , Arteria Pulmonar/diagnóstico por imagen , Taquicardia Paroxística/diagnóstico , Adenosina
2.
Am J Cardiol ; 116(6): 919-24, 2015 Sep 15.
Artículo en Inglés | MEDLINE | ID: mdl-26210281

RESUMEN

Although transcatheter aortic valve replacement (TAVR) has expanded the proportion of patients with aortic stenosis (AS) who are candidates for valve replacement, some patients remain untreated, and their outcomes are not clear. We evaluated 172 consecutive patients with severe symptomatic AS referred for TAVR who declined (n = 55) or were not candidates for (n = 117) intervention. We examined clinical and echocardiographic variables associated with mortality. There were 77 deaths, and mean follow-up was 17.9 ± 10.9 months for survivors. Mortality rate at 1 and 2 years was 39.2% and 52.6%, respectively. There was a significant difference in mortality rate between patients who declined the procedure and those who were not candidates (p = 0.001), with 1-year mortality rates of 20.6% and 48.4%, respectively. On multivariate analysis, 4 variables were independently associated with all-cause mortality: New York Heart Association Class IV heart failure (hazard ratio [HR] 2.6, 95% confidence interval [CI] 1.6 to 4.2, p <0.001), glomerular filtration rate <48 ml/min (HR 2.1, 95% CI 1.3 to 3.4, p = 0.002), albumin <3.9 g/dl (HR 1.9, 95% CI 1.2 to 3.1, p = 0.007), and ejection fraction <50% (HR 1.9, 95% CI 1.4 to 3.0, p = 0.01). In this new era with expanded treatment options, patients with severe symptomatic AS who remain untreated after referral for TAVR experience a mortality rate of 39% at 1 year. The presence of advanced heart failure, renal dysfunction, low albumin, and/or left ventricular dysfunction identifies patients at higher risk of mortality.


Asunto(s)
Estenosis de la Válvula Aórtica/mortalidad , Tasa de Filtración Glomerular , Insuficiencia Cardíaca/epidemiología , Albúmina Sérica , Volumen Sistólico , Reemplazo de la Válvula Aórtica Transcatéter , Disfunción Ventricular Izquierda/epidemiología , Anciano , Anciano de 80 o más Años , Estenosis de la Válvula Aórtica/cirugía , Estudios de Cohortes , Femenino , Insuficiencia Cardíaca/fisiopatología , Humanos , Masculino , Análisis Multivariante , Selección de Paciente , Modelos de Riesgos Proporcionales , Derivación y Consulta , Estudios Retrospectivos , Factores de Riesgo , Índice de Severidad de la Enfermedad , Negativa del Paciente al Tratamiento , Disfunción Ventricular Izquierda/fisiopatología
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