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1.
Prolonged and tunable residence time using reversible covalent kinase inhibitors.
Nat Chem Biol;
11(7): 525-31, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-26006010
2.
Phase 1 clinical trial evaluating safety, exposure and pharmacodynamics of BTK inhibitor tolebrutinib (PRN2246, SAR442168).
Clin Transl Sci;
15(2): 442-450, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34724345
3.
Discovery of the Irreversible Covalent FGFR Inhibitor 8-(3-(4-Acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (PRN1371) for the Treatment of Solid Tumors.
J Med Chem;
60(15): 6516-6527, 2017 08 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28665128
4.
The Irreversible Covalent Fibroblast Growth Factor Receptor Inhibitor PRN1371 Exhibits Sustained Inhibition of FGFR after Drug Clearance.
Mol Cancer Ther;
16(12): 2668-2676, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28978721
5.
Determination of equilibrium constant of amino carbamate adduct formation in sisomicin by a high pH based high performance liquid chromatography.
J Pharm Biomed Anal;
111: 126-30, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25880243
6.
Hydrophobic vancomycin derivatives with improved ADME properties: discovery of telavancin (TD-6424).
J Antibiot (Tokyo);
57(5): 326-36, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15303493
7.
A high pH based reversed-phase high performance liquid chromatographic method for the analysis of aminoglycoside plazomicin and its impurities.
J Pharm Biomed Anal;
66: 75-84, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22459505
8.
Telavancin, a multifunctional lipoglycopeptide, disrupts both cell wall synthesis and cell membrane integrity in methicillin-resistant Staphylococcus aureus.
Antimicrob Agents Chemother;
49(3): 1127-34, 2005 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15728913
9.
Increasing the efficiency of pharmacokinetic sample procurement, preparation and analysis by liquid chromatography/tandem mass spectrometry.
Rapid Commun Mass Spectrom;
18(10): 1066-72, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15150829
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