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1.

Human brain organogenesis: Toward a cellular understanding of development and disease.

Kelley, Kevin W; PaÈca, Sergiu P.

Cell; 185(1): 42-61, 2022 01 06.

Artículo en Inglés | MEDLINE | ID: mdl-34774127

2.

Generation of Functional Human 3D Cortico-Motor Assembloids.

Andersen, Jimena; Revah, Omer; Miura, Yuki; Thom, Nicholas; Amin, Neal D; Kelley, Kevin W; Singh, Mandeep; Chen, Xiaoyu; Thete, Mayuri Vijay; Walczak, Elisabeth M; Vogel, Hannes; Fan, H Christina; Pasca, Sergiu P.

Cell; 183(7): 1913-1929.e26, 2020 12 23.

Artículo en Inglés | MEDLINE | ID: mdl-33333020

3.

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.

Lui, Hansen; Zhang, Jiasheng; Makinson, Stefanie R; Cahill, Michelle K; Kelley, Kevin W; Huang, Hsin-Yi; Shang, Yulei; Oldham, Michael C; Martens, Lauren Herl; Gao, Fuying; Coppola, Giovanni; Sloan, Steven A; Hsieh, Christine L; Kim, Charles C; Bigio, Eileen H; Weintraub, Sandra; Mesulam, Marek-Marsel; Rademakers, Rosa; Mackenzie, Ian R; Seeley, William W; Karydas, Anna; Miller, Bruce L; Borroni, Barbara; Ghidoni, Roberta; Farese, Robert V; Paz, Jeanne T; Barres, Ben A; Huang, Eric J.

Cell; 165(4): 921-35, 2016 May 05.

Artículo en Inglés | MEDLINE | ID: mdl-27114033

4.

Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment.

Meng, Xiangling; Yao, David; Imaizumi, Kent; Chen, Xiaoyu; Kelley, Kevin W; Reis, Noah; Thete, Mayuri Vijay; Arjun McKinney, Arpana; Kulkarni, Shravanti; Panagiotakos, Georgia; Bassik, Michael C; PaÈca, Sergiu P.

Nature; 622(7982): 359-366, 2023 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-37758944

5.

Maturation and circuit integration of transplanted human cortical organoids.

Revah, Omer; Gore, Felicity; Kelley, Kevin W; Andersen, Jimena; Sakai, Noriaki; Chen, Xiaoyu; Li, Min-Yin; Birey, Fikri; Yang, Xiao; Saw, Nay L; Baker, Samuel W; Amin, Neal D; Kulkarni, Shravanti; Mudipalli, Rachana; Cui, Bianxiao; Nishino, Seiji; Grant, Gerald A; Knowles, Juliet K; Shamloo, Mehrdad; Huguenard, John R; Deisseroth, Karl; PaÈca, Sergiu P.

Nature; 610(7931): 319-326, 2022 10.

Artículo en Inglés | MEDLINE | ID: mdl-36224417

6.

Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency.

Zhang, Jiasheng; Velmeshev, Dmitry; Hashimoto, Kei; Huang, Yu-Hsin; Hofmann, Jeffrey W; Shi, Xiaoyu; Chen, Jiapei; Leidal, Andrew M; Dishart, Julian G; Cahill, Michelle K; Kelley, Kevin W; Liddelow, Shane A; Seeley, William W; Miller, Bruce L; Walther, Tobias C; Farese, Robert V; Taylor, J Paul; Ullian, Erik M; Huang, Bo; Debnath, Jayanta; Wittmann, Torsten; Kriegstein, Arnold R; Huang, Eric J.

Nature; 588(7838): 459-465, 2020 12.

Artículo en Inglés | MEDLINE | ID: mdl-32866962

7.

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults.

Sorrells, Shawn F; Paredes, Mercedes F; Cebrian-Silla, Arantxa; Sandoval, Kadellyn; Qi, Dashi; Kelley, Kevin W; James, David; Mayer, Simone; Chang, Julia; Auguste, Kurtis I; Chang, Edward F; Gutierrez, Antonio J; Kriegstein, Arnold R; Mathern, Gary W; Oldham, Michael C; Huang, Eric J; Garcia-Verdugo, Jose Manuel; Yang, Zhengang; Alvarez-Buylla, Arturo.

Nature; 555(7696): 377-381, 2018 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-29513649

8.

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity.

Molofsky, Anna V; Kelley, Kevin W; Tsai, Hui-Hsin; Redmond, Stephanie A; Chang, Sandra M; Madireddy, Lohith; Chan, Jonah R; Baranzini, Sergio E; Ullian, Erik M; Rowitch, David H.

Nature; 509(7499): 189-94, 2014 May 08.

Artículo en Inglés | MEDLINE | ID: mdl-24776795

9.

Secretagogin is Expressed by Developing Neocortical GABAergic Neurons in Humans but not Mice and Increases Neurite Arbor Size and Complexity.

Raju, Chandrasekhar S; Spatazza, Julien; Stanco, Amelia; Larimer, Phillip; Sorrells, Shawn F; Kelley, Kevin W; Nicholas, Cory R; Paredes, Mercedes F; Lui, Jan H; Hasenstaub, Andrea R; Kriegstein, Arnold R; Alvarez-Buylla, Arturo; Rubenstein, John L; Oldham, Michael C.

Cereb Cortex; 28(6): 1946-1958, 2018 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-28449024

10.

Deconstructing intratumoral heterogeneity through multiomic and multiscale analysis of serial sections.

Schupp, Patrick G; Shelton, Samuel J; Brody, Daniel J; Eliscu, Rebecca; Johnson, Brett E; Mazor, Tali; Kelley, Kevin W; Potts, Matthew B; McDermott, Michael W; Huang, Eric J; Lim, Daniel A; Pieper, Russell O; Berger, Mitchel S; Costello, Joseph F; Phillips, Joanna J; Oldham, Michael C.

bioRxiv; 2024 Mar 18.

Artículo en Inglés | MEDLINE | ID: mdl-37645893

11.

Expression profiling of Aldh1l1-precursors in the developing spinal cord reveals glial lineage-specific genes and direct Sox9-Nfe2l1 interactions.

Molofsky, Anna V; Glasgow, Stacey M; Chaboub, Lesley S; Tsai, Hui-Hsin; Murnen, Alice T; Kelley, Kevin W; Fancy, Stephen P J; Yuen, Tracy J; Madireddy, Lohith; Baranzini, Sergio; Deneen, Benjamin; Rowitch, David H; Oldham, Michael C.

Glia; 61(9): 1518-32, 2013 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-23840004

12.

Generating human neural diversity with a multiplexed morphogen screen in organoids.

Amin, Neal D; Kelley, Kevin W; Hao, Jin; Miura, Yuki; Narazaki, Genta; Li, Tommy; McQueen, Patrick; Kulkarni, Shravanti; Pavlov, Sergey; Pasca, Sergiu P.

bioRxiv; 2023 Jun 01.

Artículo en Inglés | MEDLINE | ID: mdl-37398073

13.

Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes.

Kelley, Kevin W; Nakao-Inoue, Hiromi; Molofsky, Anna V; Oldham, Michael C.

Nat Neurosci; 21(9): 1171-1184, 2018 09.

Artículo en Inglés | MEDLINE | ID: mdl-30154505

14.

Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength.

Kelley, Kevin W; Ben Haim, Lucile; Schirmer, Lucas; Tyzack, Giulia E; Tolman, Michaela; Miller, John G; Tsai, Hui-Hsin; Chang, Sandra M; Molofsky, Anna V; Yang, Yongjie; Patani, Rickie; Lakatos, Andras; Ullian, Erik M; Rowitch, David H.

Neuron; 98(2): 306-319.e7, 2018 04 18.

Artículo en Inglés | MEDLINE | ID: mdl-29606582

15.

Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development.

Vainchtein, Ilia D; Chin, Gregory; Cho, Frances S; Kelley, Kevin W; Miller, John G; Chien, Elliott C; Liddelow, Shane A; Nguyen, Phi T; Nakao-Inoue, Hiromi; Dorman, Leah C; Akil, Omar; Joshita, Satoru; Barres, Ben A; Paz, Jeanne T; Molofsky, Ari B; Molofsky, Anna V.

Science; 359(6381): 1269-1273, 2018 03 16.

Artículo en Inglés | MEDLINE | ID: mdl-29420261

16.

Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity.

Schirmer, Lucas; Möbius, Wiebke; Zhao, Chao; Cruz-Herranz, Andrés; Ben Haim, Lucile; Cordano, Christian; Shiow, Lawrence R; Kelley, Kevin W; Sadowski, Boguslawa; Timmons, Garrett; Pröbstel, Anne-Katrin; Wright, Jackie N; Sin, Jung Hyung; Devereux, Michael; Morrison, Daniel E; Chang, Sandra M; Sabeur, Khalida; Green, Ari J; Nave, Klaus-Armin; Franklin, Robin Jm; Rowitch, David H.

Elife; 72018 09 11.

Artículo en Inglés | MEDLINE | ID: mdl-30204081

17.

Astrocytes: The Final Frontier.

Kelley, Kevin W; Rowitch, David H.

Neuron; 89(1): 1-2, 2016 Jan 06.

Artículo en Inglés | MEDLINE | ID: mdl-26748083

18.

Scrutinizing disease states and regulation in human microglia.

Kelley, Kevin W; PaÈca, Sergiu P.

Nat Genet; 53(6): 766-767, 2021 06.

Artículo en Inglés | MEDLINE | ID: mdl-34083790

19.

Distinct and separable roles for EZH2 in neurogenic astroglia.

Hwang, William W; Salinas, Ryan D; Siu, Jason J; Kelley, Kevin W; Delgado, Ryan N; Paredes, Mercedes F; Alvarez-Buylla, Arturo; Oldham, Michael C; Lim, Daniel A.

Elife; 3: e02439, 2014 May 27.

Artículo en Inglés | MEDLINE | ID: mdl-24867641

20.

Does Adult Neurogenesis Persist in the Human Hippocampus?

Paredes, Mercedes F; Sorrells, Shawn F; Cebrian-Silla, Arantxa; Sandoval, Kadellyn; Qi, Dashi; Kelley, Kevin W; James, David; Mayer, Simone; Chang, Julia; Auguste, Kurtis I; Chang, Edward F; Gutierrez Martin, Antonio J; Kriegstein, Arnold R; Mathern, Gary W; Oldham, Michael C; Huang, Eric J; Garcia-Verdugo, Jose Manuel; Yang, Zhengang; Alvarez-Buylla, Arturo.

Cell Stem Cell; 23(6): 780-781, 2018 12 06.

Artículo en Inglés | MEDLINE | ID: mdl-30526879

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