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1.

Discovery of ginisortamab, a potent and novel anti-gremlin-1 antibody in clinical development for the treatment of cancer.

Davies, Gareth C G; Dedi, Neesha; Jones, Paul S; Kevorkian, Lara; McMillan, David; Ottone, Cristina; Schulze, Monika-Sarah E D; Scott-Tucker, Anthony; Tewari, Roohi; West, Shauna; Wright, Michael; Rowley, Tania F.

MAbs; 15(1): 2289681, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-38084840

2.

MMP28 gene expression is regulated by Sp1 transcription factor acetylation.

Swingler, Tracey E; Kevorkian, Lara; Culley, Kirsty L; Illman, Sara A; Young, David A; Parker, Andrew E; Lohi, Jouko; Clark, Ian M.

Biochem J; 427(3): 391-400, 2010 Apr 14.

Artículo en Inglés | MEDLINE | ID: mdl-20144149

3.

Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration.

Smith, Bryan; Kiessling, Andrea; Lledo-Garcia, Rocio; Dixon, Kate L; Christodoulou, Louis; Catley, Matthew C; Atherfold, Paul; D'Hooghe, Lena E; Finney, Helene; Greenslade, Kevin; Hailu, Hanna; Kevorkian, Lara; Lightwood, Daniel; Meier, Christoph; Munro, Rebecca; Qureshi, Omar; Sarkar, Kaushik; Shaw, Sophie P; Tewari, Roohi; Turner, Alison; Tyson, Kerry; West, Shauna; Shaw, Stevan; Brennan, Frank R.

MAbs; 10(7): 1111-1130, 2018 10.

Artículo en Inglés | MEDLINE | ID: mdl-30130439

4.

The ADAMTS metalloproteinases.

Porter, Sarah; Clark, Ian M; Kevorkian, Lara; Edwards, Dylan R.

Biochem J; 386(Pt 1): 15-27, 2005 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-15554875

5.

Certolizumab pegol does not bind the neonatal Fc receptor (FcRn): Consequences for FcRn-mediated in vitro transcytosis and ex vivo human placental transfer.

Porter, Charlene; Armstrong-Fisher, Sylvia; Kopotsha, Tim; Smith, Bryan; Baker, Terry; Kevorkian, Lara; Nesbitt, Andrew.

J Reprod Immunol; 116: 7-12, 2016 08.

Artículo en Inglés | MEDLINE | ID: mdl-27123565

6.

Enhanced anti-tumour activity of the combination of the novel MEK inhibitor WX-554 and the novel PI3K inhibitor WX-037.

Haagensen, Emma J; Thomas, Huw D; Schmalix, Wolfgang A; Payne, Andrew C; Kevorkian, Lara; Allen, Rodger A; Bevan, Paul; Maxwell, Ross J; Newell, David R.

Cancer Chemother Pharmacol; 78(6): 1269-1281, 2016 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-27837257

7.

Characterization and regulation of ADAMTS-16.

Surridge, Alison K; Rodgers, Ursula R; Swingler, Tracey E; Davidson, Rose K; Kevorkian, Lara; Norton, Rosemary; Waters, Jasmine G; Goldring, Mary B; Parker, Andrew E; Clark, Ian M.

Matrix Biol; 28(7): 416-24, 2009 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-19635554

8.

Expression and function of matrix metalloproteinase (MMP)-28.

Rodgers, Ursula R; Kevorkian, Lara; Surridge, Alison K; Waters, Jasmine G; Swingler, Tracey E; Culley, Kirsty; Illman, Sara; Lohi, Jouko; Parker, Andrew E; Clark, Ian M.

Matrix Biol; 28(5): 263-72, 2009 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-19375502

9.

Expression profiling of metalloproteinases and their inhibitors in synovium and cartilage.

Davidson, Rose K; Waters, Jasmine G; Kevorkian, Lara; Darrah, Clare; Cooper, Adele; Donell, Simon T; Clark, Ian M.

Arthritis Res Ther; 8(4): R124, 2006.

Artículo en Inglés | MEDLINE | ID: mdl-16859525

10.

Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis.

Milner, Jennifer M; Kevorkian, Lara; Young, David A; Jones, Debra; Wait, Robin; Donell, Simon T; Barksby, Emma; Patterson, Angela M; Middleton, Jim; Cravatt, Benjamin F; Clark, Ian M; Rowan, Andrew D; Cawston, Timothy E.

Arthritis Res Ther; 8(1): R23, 2006.

Artículo en Inglés | MEDLINE | ID: mdl-16507127

11.

Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption.

Young, David A; Lakey, Rachel L; Pennington, Caroline J; Jones, Debra; Kevorkian, Lara; Edwards, Dylan R; Cawston, Timothy E; Clark, Ian M.

Arthritis Res Ther; 7(3): R503-12, 2005.

Artículo en Inglés | MEDLINE | ID: mdl-15899037

12.

Expression profiling of metalloproteinases and their inhibitors in cartilage.

Kevorkian, Lara; Young, David A; Darrah, Clare; Donell, Simon T; Shepstone, Lee; Porter, Sarah; Brockbank, Sarah M V; Edwards, Dylan R; Parker, Andrew E; Clark, Ian M.

Arthritis Rheum; 50(1): 131-41, 2004 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-14730609

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