Detalles de la búsqueda
1.
4-Phenylcoumarin derivatives as new HIV-1 NNRTIs: Design, synthesis, biological activities, and computational studies.
Bioorg Chem;
141: 106918, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37866206
2.
Novel Vulgarin Derivatives: Chemical Transformation, In Silico and In Vitro Studies.
Molecules;
28(8)2023 Apr 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-37110654
3.
New quinolone derivatives as neuropeptide S receptor antagonists: Design, synthesis, homology modeling, dynamic simulations and modulation of Gq/Gs signaling pathways.
Bioorg Chem;
111: 104817, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33848721
4.
Novel thienopyrimidine analogues as potential metabotropic glutamate receptors inhibitors and anticancer activity: Synthesis, In-vitro, In-silico, and SAR approaches.
Bioorg Chem;
109: 104729, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33676314
5.
Discovery of New Coumarin-Based Lead with Potential Anticancer, CDK4 Inhibition and Selective Radiotheranostic Effect: Synthesis, 2D & 3D QSAR, Molecular Dynamics, In Vitro Cytotoxicity, Radioiodination, and Biodistribution Studies.
Molecules;
26(8)2021 Apr 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33919867
6.
New pyrazolopyrimidine derivatives with anticancer activity: Design, synthesis, PIM-1 inhibition, molecular docking study and molecular dynamics.
Bioorg Chem;
100: 103944, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32450389
7.
Rational design of some substituted phenyl azanediyl (bis) methylene phosphonic acid derivatives as potential anticancer agents and imaging probes: Computational inputs, chemical synthesis, radiolabeling, biodistribution and gamma scintigraphy.
Bioorg Chem;
92: 103282, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31541801
8.
In Silico-Based Repositioning of Phosphinothricin as a Novel Technetium-99m Imaging Probe with Potential Anti-Cancer Activity.
Molecules;
23(2)2018 Feb 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-29473879
9.
Synthesis and Structure Activity Relationship of Some Indole Derivatives as Potential Anti-inflammatory Agents.
Acta Chim Slov;
64(4): 865-876, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29318292
10.
Design, synthesis, assessment, and molecular docking of novel pyrrolopyrimidine (7-deazapurine) derivatives as non-nucleoside hepatitis C virus NS5B polymerase inhibitors.
Bioorg Med Chem;
24(9): 2146-57, 2016 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27052365
11.
3-Substituted-4-hydroxycoumarin as a new scaffold with potent CDK inhibition and promising anticancer effect: Synthesis, molecular modeling and QSAR studies.
Bioorg Chem;
67: 116-29, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27372186
12.
Assessment of intrahepatic regulatory T cells in children with autoimmune hepatitis.
Ann Hepatol;
15(5): 682-90, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27493106
13.
New Coumarin Derivatives as Potent Selective COX-2 Inhibitors: Synthesis, Anti-Inflammatory, QSAR, and Molecular Modeling Studies.
Arch Pharm (Weinheim);
348(12): 875-88, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26462142
14.
Synthesis, Characterization and Molecular Docking of Novel Bioactive Thiazolyl-Thiazole Derivatives as Promising Cytotoxic Antitumor Drug.
Molecules;
21(1): E3, 2015 Dec 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-26703554
15.
New pyrazolylindolin-2-one based coumarin derivatives as anti-melanoma agents: design, synthesis, dual BRAFV600E/VEGFR-2 inhibition, and computational studies.
RSC Adv;
14(9): 5907-5925, 2024 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38370458
16.
A novel class of substituted spiro [quinazoline-2,1'-cyclohexane] derivatives as effective PPAR-1 inhibitors: molecular modeling, synthesis, cytotoxic and enzyme assay evaluation.
Acta Pol Pharm;
70(4): 687-708, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23923393
17.
Design, Synthesis, Molecular Docking, Dynamics and in vitro Evaluation of Novel 2-substituted-1-hydroxyethane-1, 1-bis(phosphonic acid) Derivatives as Human Farnesyl Pyrophosphate Synthase Inhibitors with Expected Anticancer Activity.
Curr Pharm Des;
29(1): 48-59, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36476435
18.
Purine analogs: synthesis, evaluation and molecular dynamics of pyrazolopyrimidines based benzothiazole as anticancer and antimicrobial CDK inhibitors.
Nucleosides Nucleotides Nucleic Acids;
42(1): 77-104, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-35949161
19.
Computational, in vitro and radiation-based in vivo studies on acetamide quinazolinone derivatives as new proposed purine nucleoside phosphorylase inhibitors for breast cancer.
Eur J Med Chem;
248: 115087, 2023 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36610250
20.
Synthesis, molecular docking and preliminary in-vitro cytotoxic evaluation of some substituted tetrahydro-naphthalene (2',3',4',6'-tetra-O-acetyl-ß-D-gluco/-galactopyranosyl) derivatives.
Molecules;
17(4): 4717-32, 2012 Apr 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-22525438